Results for the protein: NP

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
NR_DBD_TLX	cd07163	1.2e-13	12	118
NR_DBD_VDR	cd06955	9.9e-14	18	120
NR_DBD_PNR	cd06970	4.2e-12	20	106
NR_DBD_GCNF_like	cd07169	1.8e-19	20	107
NR_DBD_ERR	cd07170	8.2e-21	22	116
NR_DBD_TR2_like	cd06967	8.6e-21	23	110
NR_DBD_ER	cd07171	1.3e-28	23	104
NR_DBD_AR	cd07173	9e-62	23	104
NR_DBD_GR_PR	cd07172	3.4e-50	24	101
NR_DBD_FXR	cd06962	5.2e-17	25	108
NR_DBD_RAR	cd06964	6.2e-17	25	102
NR_DBD_EcR	cd07161	5e-19	25	115
NR_DBD_REV_ERB	cd07166	1.3e-14	25	110
NR_DBD_DHR4_like	cd07168	7.4e-17	25	107
NR_DBD_RXR	cd06956	3.3e-18	26	102
NR_DBD_CAR	cd06966	2.3e-15	26	113
NR_DBD_NGFI-B	cd06969	3.7e-21	26	100
2DBD_NR_DBD1	cd07157	8.8e-17	26	108
NR_DBD_EcR_like	cd06959	5.7e-21	27	99
NR_DBD_TR	cd06961	2.1e-19	27	109
NR_DBD_Ppar	cd06965	3.8e-13	27	111
NR_DBD_ROR	cd06968	7.4e-19	27	115
NR_DBD_PXR	cd07162	1.8e-13	27	109
NR_DBD_like	cd06916	1.8e-37	28	99
NR_DBD_PNR_like_2	cd06957	2.7e-17	28	109
NR_DBD_COUP_TF	cd06958	6e-19	28	100
NR_DBD_HNF4A	cd06960	6.6e-27	28	103
NR_DBD_GR_like	cd06963	1.4e-56	28	100
NR_DBD_PNR_like	cd07154	7e-20	28	99
NR_DBD_ER_like	cd07155	2.4e-24	28	102
NR_DBD_VDR_like	cd07156	2.3e-20	28	95
NR_DBD_Ppar_like	cd07158	6.2e-18	28	99
NR_DBD_PNR_like_1	cd07164	3.2e-20	28	105
NR_DBD_DmE78_like	cd07165	8.5e-16	28	108
NR_DBD_Lrh-1_like	cd07167	3.4e-20	28	120
2DBD_NR_DBD2	cd07179	9.6e-18	28	101
NR_LBD_Nurr1_like	cd06945	0.00039	114	360
NR_LBD_ER	cd06949	1.8e-06	137	371
NR_LBD_SF-1	cd07070	0.00099	140	371
NR_LBD_RXR_like	cd06943	3.3e-07	141	327
NR_LBD_GR_Like	cd06947	4e-177	141	386
NR_LBD_AR	cd07073	4.1e-204	141	386
NR_LBD_PR	cd07074	2.2e-123	141	388
NR_LBD_MR	cd07075	1.4e-89	141	388
NR_LBD_GR	cd07076	1.8e-107	141	388
NR_LBD_ERR	cd06946	4.3e-10	142	366
NR_LBD_DHR4_like	cd06953	0.0001	142	353
NR_LBD_ER_like	cd07068	4.7e-13	142	366
NR_LBD_HNF4_like	cd06931	2.8e-06	143	363
NR_LBD_Ftz-F1_like	cd06944	0.00061	145	352
NR_LBD_F1	cd06929	3.1e-05	167	346
NR_LBD_F2	cd06930	9.7e-63	170	338
NR_LBD	cd06157	2.9e-50	171	338
zf-C4	pfam00105	1.2e-40	26	95
Hormone_recep	pfam00104	1.6e-35	201	367
ZnF_C4	smart00399	9.1e-33	27	96
HOLI	smart00430	7.9e-35	177	338

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
OMIM	313700.0032	Disease	p.ALA189THR	PROSTATE CANCER
OMIM	313700.0011	Disease	p.ALA239THR	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0010	Disease	p.ARG240CYS	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0003	Disease	p.ARG241CYS	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0026	Disease	p.ARG307CYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0054	Disease	p.ARG308CYS	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0016	Disease	p.ARG75GLN	ANDROGEN INSENSITIVITY, PARTIAL, WITH OR WITHOUT BREAST CANCER
OMIM	313700.0015	Disease	p.ARG241HIS	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0025	Disease	p.ARG307HIS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0040	Disease	p.ARG314HIS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0019	Disease	p.ARG323HIS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0047	Disease	p.ARG194LEU	PROSTATE CANCER SUSCEPTIBILITY
OMIM	313700.0024	Disease	p.ARG76LYS	ANDROGEN INSENSITIVITY, PARTIAL, WITH BREAST CANCER
OMIM	313700.0035	Disease	p.CYS47PHE	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0031	Disease	p.GLN370ARG	PROSTATE CANCER
OMIM	313700.0043	Disease	p.GLN266GLU	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0051	Disease	p.GLY45ARG	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0057	Disease	p.GLY211GLU	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0056	Disease	p.GLY211VAL	ANDROGEN INSENSITIVITY, PARTIAL\|\|ANDROGEN INSENSITIVITY, COMPLETE, INCLUDED
OMIM	313700.0055	Disease	p.HIS157PRO	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0030	Disease	p.HIS342TYR	PROSTATE CANCER
OMIM	313700.0020	Disease	p.ILE337MET	HYPOSPADIAS 1, X-LINKED
OMIM	313700.0034	Disease	p.LEU175ARG	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0050	Disease	p.LEU180PHE	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0028	Disease	p.LEU144PRO	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0009	Disease	p.LYS350TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0007	Disease	p.LYS56TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0039	Disease	p.MET248ILE	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0044	Disease	p.MET275THR	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0012	Disease	p.MET254VAL	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0053	Disease	p.PHE324LEU	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0036	Disease	p.PHE50TYR	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0037	Disease	p.PRO14SER	HYPOSPADIAS 1, X-LINKED
OMIM	313700.0033	Disease	p.SER115ASN	PROSTATE CANCER
OMIM	313700.0059	Disease	p.SER208CYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0052	Disease	p.SER333PRO	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0048	Disease	p.SER356SER	ANDROGEN INSENSITIVITY SYNDROME
OMIM	313700.0027	Disease	p.THR345ALA	PROSTATE CANCER
OMIM	313700.0029	Disease	p.THR345SER	PROSTATE CANCER
OMIM	313700.0004	Disease	p.TRP185TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0006	Disease	p.TRP262TER	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0008	Disease	p.TYR229CYS	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0018	Disease	p.VAL333LEU	ANDROGEN INSENSITIVITY, PARTIAL
OMIM	313700.0013	Disease	p.VAL198MET	PROSTATE CANCER
OMIM	313700.0017	Disease	p.VAL333MET	ANDROGEN INSENSITIVITY, COMPLETE
OMIM	313700.0005	Disease	p.VAL334MET	ANDROGEN INSENSITIVITY, COMPLETE

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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