Results for the protein: O14733

Results for the Protein: O14733

6831583

5609

MAP2K7

NCBI, UniProt

MP2K7_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 7; Short=MAP kinase kinase 7; Short=MAPKK 7; AltName: Full=JNK-activating kinase 2; AltName: Full=MAPK/ERK kinase 7; Short=MEK 7; AltName: Full=Stress-activated protein kinase kinase 4; Short=SAPK kinase 4; Short=SAPKK-4; Short=SAPKK4; AltName: Full=c-Jun N-terminal kinase kinase 2; Short=JNK kinase 2; Short=JNKK 2

			0 7 0 1 6

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Swiss-Prot Protein: O14733

Identical to: NP_660186

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	2.2e-06	73	419
STKc_ROCK2	cd05621	4.6e-06	76	419
STKc_ROCK1	cd05622	5.3e-05	76	418
PTKc_FAK	cd05056	3e-08	90	385
PTKc_DDR2	cd05095	0.00072	91	382
STKc_TAO3	cd06633	4.3e-12	97	412
STKc_PAK_I	cd06647	6.2e-16	97	405
STKc_PAK_II	cd06648	8e-14	97	398
STKc_PAK1	cd06654	4.9e-09	97	407
STKc_PAK2	cd06655	3.3e-09	97	408
STKc_PAK3	cd06656	2.1e-09	97	409
PTKc_DDR_like	cd05097	0.00072	98	382
STKc_TAO1	cd06635	6.9e-13	100	412
STKc_myosinIIIA	cd06638	1.5e-21	100	380
STKc_MAP4K4_6	cd06636	4.1e-23	101	380
PKc_MKK7	cd06618	1.1e-248	104	400
STKc_p38	cd07851	2.6e-07	105	402
STKc_p38gamma_MAPK12	cd07880	5e-05	105	419
STKc_ERK5	cd07855	4.7e-05	106	412
STKc_myosinIIIB	cd06639	1.3e-20	107	381
STKc_PAK5	cd06658	8.5e-08	107	395
STKc_CDK9	cd07865	1.4e-05	107	380
STKc_STK10_LOK	cd06644	5.1e-27	108	397
STKc_PAK6	cd06659	7.2e-11	108	404
STKc_Sty1_Hog1	cd07856	1.9e-07	108	402
STKc_PAK4	cd06657	5.6e-08	109	399
STKc_PCTAIRE2	cd07872	6.6e-06	109	413
STKc_PAK	cd06614	3.3e-21	110	386
STKc_MAP4K3	cd06645	3.5e-26	110	379
STKc_MAP4K5	cd06646	9.1e-21	110	379
STKc_p38alpha_MAPK14	cd07877	0.00038	110	406
PTKc_FGFR	cd05053	0.00018	111	385
PTKc_EGFR_like	cd05057	1.2e-07	111	387
PTKc_EphR_A10	cd05064	4.4e-05	111	384
PTKc_HER2	cd05109	3.3e-08	111	391
STKc_TNIK	cd06637	5.8e-25	111	380
STKc_ASK	cd06624	2.9e-23	111	380
STKc_JNK	cd07850	0.00011	111	412
PTKc_HER4	cd05110	9.3e-06	112	402
PTKc_EGFR	cd05108	1.2e-07	112	416
PTKc_InsR_like	cd05032	1.9e-09	113	382
PTKc_ALK_LTK	cd05036	7.3e-09	113	382
PTKc_Abl	cd05052	5.6e-09	113	379
PTKc_InsR	cd05061	2.8e-05	113	399
PTKc_IGF-1R	cd05062	0.00014	113	382
PTKc_EphR_A	cd05066	1.1e-05	113	380
PTKc_Lck_Blk	cd05067	1.1e-05	113	383
PTKc_Frk_like	cd05068	9.9e-14	113	378
PTKc_Yes	cd05069	1.2e-06	113	383
PTKc_Fyn_Yrk	cd05070	4.8e-06	113	383
PTKc_Src	cd05071	1e-06	113	385
PTKc_Hck	cd05073	5.5e-06	113	383
PTKc_Csk	cd05082	2.2e-05	113	378
PTKc_Lyn	cd05072	1.8e-06	113	383
PTKc_Tie2	cd05088	1.8e-06	113	403
PTKc_Chk	cd05083	4.5e-06	113	381
STKc_TEY_MAPK_plant	cd07858	2.7e-05	113	419
STKc_CDK12	cd07864	4.1e-08	113	380
PTKc_Trk	cd05049	0.00018	114	377
PTKc_Musk	cd05050	1.7e-06	114	377
PTKc_Ror1	cd05090	0.00041	114	383
STKc_TAO	cd06607	3.4e-12	114	412
STKc_TAO2	cd06634	1.5e-12	114	413
STKc_SLK	cd06643	9.1e-22	114	403
PKc_MEK2	cd06649	6.1e-47	114	408
PKc_MEK1	cd06650	1.3e-48	114	410
STKc_PCTAIRE_like	cd07844	1.6e-06	114	417
PTKc_EphR	cd05033	1.6e-07	115	380
PTKc_Jak_rpt2	cd05038	8.1e-07	115	382
PTKc_EphR_B	cd05065	6e-07	115	380
PTKc_Jak1_rpt2	cd05079	0.00051	115	387
PTK_HER3	cd05111	2.7e-07	115	387
PTKc_Itk	cd05112	8e-10	115	379
PTKc_Btk_Bmx	cd05113	1e-08	115	379
PTKc_Tec_Rlk	cd05114	8e-08	115	379
STKc_CDK10	cd07845	2e-08	115	416
STKc_PFTAIRE2	cd07870	4.7e-05	115	394
STKc_PCTAIRE3	cd07871	6.8e-06	115	417
STKc_PCTAIRE1	cd07873	4.4e-05	115	406
PTKc_Src_like	cd05034	1.3e-09	116	383
PTKc_EphR_A2	cd05063	8.6e-05	116	379
PTKc_Jak2_Jak3_rpt2	cd05081	2e-06	116	382
PKc_MKK4	cd06616	1.8e-128	116	398
STKc_MST3	cd06641	3.7e-29	116	395
STKc_CDK7	cd07841	2.4e-09	116	387
STKc_BUR1	cd07866	9.9e-05	116	380
PTKc_Csk_like	cd05039	0.00015	117	381
PTKc_Tie1	cd05089	2.4e-05	117	402
STKc_SLK_like	cd06611	1.9e-15	117	392
STKc_CDC2L1	cd07843	7.6e-07	117	394
STKc_Nek6_Nek7	cd08224	2.5e-10	117	383
STKc_Nek6	cd08228	4e-09	117	383
STKc_Nek7	cd08229	3e-11	117	385
STKc_phototropin_lik	cd05574	6.8e-08	118	396
STKc_ROCK_NDR_like	cd05573	1.8e-08	118	419
STKc_PKA	cd05580	2.3e-09	118	397
STKc_PDK1	cd05581	1.9e-14	118	380
STKc_DMPK_like	cd05597	7e-07	118	419
STKc_LATS	cd05598	0.00016	118	418
STKc_NDR_like	cd05599	7.6e-05	118	419
STKc_CRIK	cd05601	8.5e-10	118	419
STKc_Sid2p_Dbf2p	cd05600	1.1e-06	118	419
STKc_MAST	cd05609	6.8e-08	118	419
STKc_PRKX_like	cd05612	2.3e-07	118	416
STKc_MRCK_alpha	cd05623	3.5e-06	118	418
STKc_MRCK_beta	cd05624	2.1e-06	118	419
STKc_NDR2	cd05627	0.00093	118	419
STKc_NDR1	cd05628	1.4e-05	118	419
PKc_MAPKK	cd06605	8.2e-179	118	385
STKc_myosinIII_like	cd06608	1.1e-18	118	380
STKc_MST3_like	cd06609	1.2e-22	118	395
STKc_OSR1_SPAK	cd06610	4.3e-25	118	380
STKc_MAP4K3_like	cd06613	1.4e-32	118	379
PKc_MKK3_6	cd06617	2.9e-124	118	399
PKc_MEK	cd06615	9.8e-63	118	398
PKc_MKK5	cd06619	8.9e-57	118	405
PKc_MAPKK_Byr1_like	cd06620	1.7e-51	118	394
PKc_MAPKK_Pek1_like	cd06621	2.4e-43	118	398
PKc_MAPKK_PBS2_like	cd06622	3.4e-72	118	401
PKc_MAPKK_plant_like	cd06623	1.9e-66	118	385
STKc_CDKL	cd07833	7.3e-12	118	380
STKc_CDKL2_3	cd07846	2.2e-09	118	380
STKc_CDKL1_4	cd07847	4.5e-19	118	417
STKc_CDKL5	cd07848	5.2e-05	118	394
STKc_ERK1_2_like	cd07849	0.00036	118	399
STKc_CdkB_plant	cd07837	2.8e-09	118	381
STKc_CDK6	cd07862	4.6e-05	118	391
PK_STRAD	cd08216	2.6e-08	118	396
SPS1	COG0515	9.4e-27	118	419
PTKc_RET	cd05045	0.00026	119	382
PTKc_Tec_like	cd05059	1.2e-09	119	379
PKc_STE	cd05122	7.1e-60	119	379
PTKc_Srm_Brk	cd05148	9.3e-06	119	380
STKc_Yank1	cd05578	3.8e-15	119	380
STKc_MSK_N	cd05583	1.3e-09	119	396
STKc_cPKC	cd05587	4.4e-06	119	419
STKc_GRK4_like	cd05605	8.4e-09	119	418
STKc_MSK1_N	cd05613	7.2e-08	119	396
STKc_MSK2_N	cd05614	5.2e-08	119	416
STKc_cPKC_alpha	cd05615	3.7e-06	119	419
STKc_cPKC_beta	cd05616	4.8e-05	119	419
STKc_GRK6	cd05630	7.1e-06	119	418
STKc_GRK4	cd05631	1.3e-05	119	418
STKc_GRK5	cd05632	4.9e-07	119	418
STKc_MAPKKK	cd06606	1.9e-40	119	380
STKc_MST4	cd06640	2.4e-32	119	395
STKc_STK25-YSK1	cd06642	1.7e-35	119	405
STKc_CCRK	cd07832	3.1e-11	119	381
STKc_MAPK	cd07834	2.8e-08	119	402
STKc_Pho85	cd07836	1.3e-05	119	418
STKc_CDK5	cd07839	2.4e-07	119	394
STKc_CDK8_like	cd07842	8.5e-07	119	394
STKc_MPK1	cd07857	2.2e-05	119	409
STKc_TDY_MAPK_plant	cd07859	0.00019	119	419
STKc_CDK2_3	cd07860	2e-06	119	394
STKc_CDK1_euk	cd07861	1.2e-06	119	418
STKc_CDK4	cd07863	3.1e-06	119	394
STKc_Nek	cd08215	2.6e-22	119	380
STKc_Nek2	cd08217	2.1e-15	119	380
STKc_Nek1	cd08218	4.9e-11	119	380
STKc_Nek3	cd08219	5.5e-11	119	380
STKc_Nek8	cd08220	4.6e-09	119	380
STKc_Nek4	cd08223	5.3e-08	119	380
STKc_Nek5	cd08225	3.9e-07	119	380
PK_STRAD_alpha	cd08227	6.1e-05	119	397
STKc_Nek10	cd08528	1e-08	119	382
STKc_FA2-like	cd08529	2.1e-15	119	380
STKc_CNK2-like	cd08530	1.6e-10	119	380
PTKc_Tyk2_rpt2	cd05080	5.1e-05	120	385
STKc_CMGC	cd05118	7.8e-15	120	380
STKc_RSK_N	cd05582	3.7e-06	120	419
STKc_p70S6K	cd05584	3.8e-06	120	418
STKc_PKN	cd05589	8.8e-06	120	419
STKc_MST1_2	cd06612	4.5e-23	120	380
STKc_YSK4	cd06631	2.4e-14	120	380
STKc_CDK_like	cd07829	3.3e-13	120	380
STKc_MAK_like	cd07830	1.4e-10	120	380
STKc_CDK1_like	cd07835	2.1e-07	120	418
STKc_CDK4_6_like	cd07838	2.6e-08	120	380
STKc_CDK9_like	cd07840	5.8e-09	120	380
STKc_CDK8	cd07868	0.00077	120	418
STKc_CDC2L6	cd07867	0.00015	120	418
STKc_MEKK3_like_1	cd06653	2.9e-09	121	380
PK_STRAD_beta	cd08226	1.7e-05	121	396
PTKc_Axl_like	cd05035	6.9e-05	122	381
PTKc_Tyro3	cd05074	0.00037	122	382
STKc_MEKK3_like	cd06625	1.8e-20	122	380
STKc_Cdc7_like	cd06627	6.3e-20	122	380
STKc_MEKK2	cd06652	2.3e-08	122	381
STKc_Rim15_like	cd05611	0.00032	123	419
STKc_MEKK4	cd06626	6.4e-18	123	380
STKc_MOK	cd07831	1.3e-08	123	380
STKc_MAPK15	cd07852	1e-06	123	399
PTKc	cd00192	7.6e-12	124	379
PTKc_Ack_like	cd05040	3.5e-10	124	376
PTKc_Fes_like	cd05041	7.9e-11	124	380
PTKc_Aatyk	cd05042	0.00068	124	377
PTKc_Syk_like	cd05060	4.2e-08	124	385
PTKc_Aatyk2	cd05086	0.00033	124	377
PTKc_Fes	cd05084	5e-08	124	380
PTKc_Syk	cd05116	4.8e-08	124	384
STKc_MAPKKK_Bck1_lik	cd06629	3.1e-14	124	380
STKc_MEKK1	cd06630	2.8e-11	124	381
STKc_MEKK1_plant	cd06632	7.3e-17	124	380
STKc_Nek11	cd08222	1.7e-06	124	380
PTKc_Zap-70	cd05115	3.1e-08	125	383
STKc_NAK1_like	cd06917	4.2e-16	125	402
PKc	cd00180	8.6e-61	126	378
PTKc_c-ros	cd05044	4e-06	126	376
PTKc_Tie	cd05047	3.4e-05	126	376
PTKc_Met_Ron	cd05058	9.3e-05	126	383
PTKc_Fer	cd05085	2.7e-06	126	380
STKc_AGC	cd05123	3.5e-15	126	380
STKc_PKC	cd05570	6e-10	126	419
STKc_PKB	cd05571	2.7e-08	126	419
STKc_cGK_PKG	cd05572	2e-10	126	385
STKc_SGK	cd05575	3.6e-06	126	418
STKc_GRK	cd05577	9.8e-11	126	389
STKc_MAST_like	cd05579	1.2e-13	126	385
STKc_YPK1_like	cd05585	1.6e-07	126	419
STKc_Sck1_like	cd05586	1.1e-05	126	418
STKc_aPKC	cd05588	1.6e-06	126	419
STKc_nPKC_epsilon	cd05591	1.5e-06	126	419
STKc_nPKC_theta_delt	cd05592	2.9e-07	126	413
STKc_PKB_gamma	cd05593	7.2e-06	126	419
STKc_PKB_alpha	cd05594	1.4e-06	126	419
STKc_PKB_beta	cd05595	6.2e-05	126	419
STKc_nPKC_eta	cd05590	1.9e-05	126	419
STKc_SGK1	cd05602	9.7e-05	126	417
STKc_SGK2	cd05603	1.9e-05	126	419
STKc_SGK3	cd05604	5.3e-05	126	416
STKc_GRK7	cd05607	1.1e-09	126	396
STKc_GRK1	cd05608	1.5e-10	126	417
STKc_beta_ARK	cd05606	9.2e-10	126	405
STKc_aPKC_zeta	cd05617	3.9e-06	126	413
STKc_aPKC_iota	cd05618	3e-05	126	413
STKc_nPKC_theta	cd05619	8.7e-07	126	419
STKc_GRK3	cd05633	1.8e-08	126	401
STKc_MAPKKK_Byr2_lik	cd06628	2.6e-25	126	380
STKc_MEKK3	cd06651	7.7e-12	126	382
STKc_Nek9	cd08221	7.3e-10	126	380
Pkinase	pfam00069	1.1e-58	120	380
Pkinase_Tyr	pfam07714	3.1e-15	120	380
TyrKc	smart00219	4.4e-12	120	380
STYKc	smart00221	1.7e-59	120	380
S_TKc	smart00220	1.1e-68	130	380
KIND	smart00750	4.8e-05	200	388

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040829	Polymorphism	p.ALA195THR	N/A
Swiss-Prot	VAR_040826	Polymorphism	p.ARG138CYS	N/A
Swiss-Prot	VAR_040827	Polymorphism	p.ARG162CYS	N/A
Swiss-Prot	VAR_040828	Polymorphism	p.ARG162HIS	N/A
Swiss-Prot	VAR_040825	Polymorphism	p.ASN118SER	N/A
dbSNP	rs28395770	Polymorphism	p.GLU116LYS	N/A
Swiss-Prot	VAR_029890	Polymorphism	p.LEU259PHE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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