Results for the protein: NP

Results for the Protein: NP_001020414

68800350

3654

IRAK1

NCBI

interleukin-1 receptor-associated kinase 1 isoform 3 [Homo sapiens]

			0 5 0 5 0

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RefSeq Protein: NP_001020414

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Death_IRAK1	cd08794	2.1e-68	17	100
Death_IRAK2	cd08795	2.1e-13	17	100
Death_IRAK-M	cd08796	4.5e-06	17	100
STKc_PAK	cd06614	2.6e-07	192	446
STKc_TAO2	cd06634	0.00014	197	511
STKc_PAK_II	cd06648	0.00019	198	463
PTKc_Chk	cd05083	1.7e-05	200	478
PTKc_Tie2	cd05088	1.8e-05	200	484
PTKc_FGFR	cd05053	0.00017	201	447
STKc_CDK10	cd07845	7.9e-07	201	535
PTKc_ALK_LTK	cd05036	1.1e-06	203	444
PTKc_Abl	cd05052	7e-06	203	480
PTKc_FAK	cd05056	4.6e-06	203	467
PTKc_InsR	cd05061	0.001	203	468
PTKc_IGF-1R	cd05062	0.00097	203	461
PTKc_Lck_Blk	cd05067	0.00012	203	523
PTKc_Frk_like	cd05068	7e-08	203	487
PTKc_Yes	cd05069	6.2e-06	203	476
PTKc_Fyn_Yrk	cd05070	3.5e-05	203	476
PTKc_Src	cd05071	5.1e-05	203	478
PTKc_Lyn	cd05072	3.1e-05	203	476
PTKc_Hck	cd05073	3.5e-05	203	476
STKc_ASK	cd06624	3.5e-05	203	478
PTKc_InsR_like	cd05032	0.0002	204	461
PTKc_Src_like	cd05034	2.4e-08	204	468
PTKc_Ror	cd05048	8.8e-10	204	476
PTKc_Trk	cd05049	3e-09	204	444
PTKc_Musk	cd05050	8.4e-07	204	501
PTKc_Ror1	cd05090	4.5e-05	204	482
PTKc_Ror2	cd05091	4.6e-05	204	482
PTKc_TrkA	cd05092	6.5e-06	204	484
PTKc_TrkB	cd05093	0.00045	204	494
PTKc_TrkC	cd05094	0.00023	204	532
PTKc_DDR2	cd05095	0.00054	204	491
PTKc_DDR_like	cd05097	0.00066	204	491
STKc_MAPKKK	cd06606	7.7e-13	204	479
PTK_Ryk	cd05043	0.00038	205	418
PTKc_Tec_like	cd05059	6.6e-06	205	447
PTKc_Itk	cd05112	8.5e-07	205	477
PTKc_Btk_Bmx	cd05113	4e-05	205	473
PTKc_Tec_Rlk	cd05114	0.0001	205	477
STKc_BUR1	cd07866	0.00029	205	444
PTKc_Jak_rpt2	cd05038	3.9e-06	206	476
PTKc_EphR_A10	cd05064	0.00021	206	480
STKc_CDK12	cd07864	0.00035	206	525
PTKc_Srm_Brk	cd05148	1.3e-05	207	445
STKc_STK25-YSK1	cd06642	0.00071	207	503
STKc_CDC2L1	cd07843	0.00059	207	410
PTKc_EphR_B	cd05065	2.9e-05	208	476
STKc_MST1_2	cd06612	5.7e-06	208	429
STKc_MAP4K3_like	cd06613	1.1e-05	208	464
PKc_MKK4	cd06616	2.4e-05	208	503
STKc_PCTAIRE_like	cd07844	0.00017	208	518
STKc_PFTAIRE2	cd07870	0.00037	208	520
PTKc_EphR	cd05033	3.8e-07	209	443
STKc_TEY_MAPK_plant	cd07858	0.00047	209	560
STKc_Nek6_Nek7	cd08224	1.3e-05	209	484
STKc_Nek6	cd08228	0.00016	209	478
STKc_Nek7	cd08229	1.6e-06	209	478
PTKc_Tie1	cd05089	0.00029	210	497
STKc_PDK1	cd05581	1e-06	210	472
PKc_MAPKK	cd06605	0.00015	210	470
STKc_MST3_like	cd06609	1.7e-05	210	442
PKc_MKK3_6	cd06617	0.00041	210	464
STKc_MEKK3_like	cd06625	1.3e-06	210	469
STKc_CDKL1_4	cd07847	1.9e-06	210	518
SPS1	COG0515	1.2e-24	210	632
PKc_STE	cd05122	7.9e-07	211	469
STKc_Yank1	cd05578	2.9e-07	211	469
STKc_GRK4_like	cd05605	0.00019	211	533
STKc_Cdc7_like	cd06627	5.4e-08	211	434
STKc_MAPKKK_Byr2_lik	cd06628	5.2e-05	211	490
STKc_MEKK3	cd06651	0.00014	211	507
STKc_CCRK	cd07832	5.8e-06	211	484
STKc_Pho85	cd07836	0.00063	211	518
STKc_CDK7	cd07841	8.1e-06	211	432
STKc_CDKL2_3	cd07846	1.4e-05	211	525
STKc_CDK2_3	cd07860	0.00077	211	504
STKc_Nek	cd08215	3e-11	211	469
STKc_Nek2	cd08217	0.00094	211	401
STKc_Nek1	cd08218	9.6e-05	211	478
STKc_Nek11	cd08222	0.00019	211	469
STKc_Nek4	cd08223	0.00023	211	478
STKc_Nek3	cd08219	2e-05	211	480
STKc_Nek5	cd08225	0.0002	211	478
STKc_FA2-like	cd08529	1.1e-07	211	469
STKc_CNK2-like	cd08530	0.0004	211	459
PTKc_Jak2_Jak3_rpt2	cd05081	0.00011	212	480
STKc_CMGC	cd05118	1.4e-06	212	444
PKc_MAPKK_plant_like	cd06623	2.9e-07	212	471
STKc_CDK_like	cd07829	6.9e-09	212	434
STKc_MAK_like	cd07830	8.5e-06	212	434
STKc_CDK1_like	cd07835	0.00059	212	505
STKc_CDK4_6_like	cd07838	0.001	212	396
STKc_CDK9_like	cd07840	5.1e-06	212	413
PTKc_Csk_like	cd05039	1.2e-06	213	449
PTK_Jak2_Jak3_rpt1	cd05078	9.7e-06	214	477
PKc_MAPKK_PBS2_like	cd06622	0.00019	214	502
STKc_MEKK1	cd06630	0.00032	214	454
PTKc_Fer	cd05085	1.1e-06	215	478
STKc_MEKK4	cd06626	7.2e-07	215	479
STKc_MAPKKK_Bck1_lik	cd06629	8.5e-07	215	505
PTKc	cd00192	3.2e-11	216	473
PTKc_Fes_like	cd05041	8e-08	216	461
PTKc_c-ros	cd05044	4.1e-05	216	465
PTKc_Ack_like	cd05040	4e-08	216	436
PTKc_Tyk2_rpt2	cd05080	0.00036	216	504
PTKc_Zap-70	cd05115	0.00056	216	478
STKc_myosinIII_like	cd06608	3.1e-05	216	434
PTKc_Fes	cd05084	4e-06	217	487
STKc_OSR1_SPAK	cd06610	1.1e-05	217	446
STKc_CDKL	cd07833	1.6e-05	217	408
PKc	cd00180	1.5e-39	218	449
PTKc_Aatyk	cd05042	0.0002	218	468
PTKc_Tie	cd05047	4.8e-05	218	477
PTKc_Met_Ron	cd05058	0.00013	218	482
STKc_AGC	cd05123	1.5e-05	218	483
STKc_PKB	cd05571	0.00083	218	532
STKc_GRK	cd05577	0.00041	218	464
STKc_MAST_like	cd05579	0.00047	218	444
STKc_GRK7	cd05607	0.00093	218	507
STKc_GRK1	cd05608	1.7e-05	218	510
STKc_nPKC_theta	cd05619	0.00076	218	527
STKc_SLK_like	cd06611	0.00082	218	421
STKc_YSK4	cd06631	1.3e-06	218	469
STKc_MEKK1_plant	cd06632	3.4e-05	218	445
STKc_NAK1_like	cd06917	0.001	218	447
STKc_Nek9	cd08221	0.00066	218	450
Death	pfam00531	6.6e-12	28	103
Pkinase	pfam00069	1.1e-19	212	469
Pkinase_Tyr	pfam07714	7.7e-15	212	459
STYKc	smart00221	7.8e-26	212	499
TyrKc	smart00219	2.8e-13	212	469
S_TKc	smart00220	5.6e-12	222	483

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs11465830	Polymorphism	p.ARG194HIS	N/A
dbSNP	rs10127175	Polymorphism	p.CYS203SER	N/A
dbSNP	rs1059702	Polymorphism	p.PHE196SER	N/A
dbSNP	rs1059703	Polymorphism	p.SER453LEU	N/A
dbSNP	rs11465829	Polymorphism	p.THR113ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258