Results for the protein: O95996

Results for the Protein: O95996

74722250

10297

APC2

NCBI, UniProt

APC2_HUMAN RecName: Full=Adenomatous polyposis coli protein 2; AltName: Full=Adenomatous polyposis coli protein-like; Short=APC-like

			0 5 0 3 2

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Default View: Suppressor_APC - pfam11414 ARM - smart00185 ARM - cd00020 Arm - pfam00514 APC_crr - pfam05923 SAMP - pfam05924 APC_basic - pfam05956	Swiss-Prot Protein: O95996 Identical to: NP_005874 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ARM	cd00020	8.4e-18	569	696
Arm	pfam00514	5.4e-05	521	562
Arm	pfam00514	1.1e-09	614	654
Arm	pfam00514	0.0003	656	696
Suppressor_APC	pfam11414	2.5e-37	123	206
ARM	smart00185	3.4e-05	424	475
ARM	smart00185	0.00098	520	562
ARM	smart00185	1.7e-09	614	654
APC_crr	pfam05923	4.5e-07	1052	1077
APC_crr	pfam05923	2.9e-06	1144	1169
APC_crr	pfam05923	4.1e-05	1257	1282
SAMP	pfam05924	3.6e-07	1337	1357
APC_crr	pfam05923	7.4e-07	1385	1410
SAMP	pfam05924	5.7e-06	1625	1643
APC_basic	pfam05956	3e-207	1786	2123

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_037703	Polymorphism	p.ALA562SER	N/A
dbSNP	rs61735597	Polymorphism	p.ALA949THR	N/A
dbSNP	rs116169601	Polymorphism	p.ARG1456PRO	N/A
Swiss-Prot	VAR_037704	Polymorphism	p.GLY2003SER	N/A
dbSNP	rs265277	Polymorphism	p.SER2241ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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