Results for the protein: O14654

Results for the Protein: O14654

74762093

8471

IRS4

NCBI, UniProt

IRS4_HUMAN RecName: Full=Insulin receptor substrate 4; Short=IRS-4; AltName: Full=160 kDa phosphotyrosine protein; Short=py160; AltName: Full=Phosphoprotein of 160 kDa; Short=pp160

			0 9 0 4 5

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Default View: PH_IRS - cd01257 PH - smart00233 PH - pfam00169 PH - cd00821 PTB_IRS - cd01204 PTBI - smart00310 - cd00824 IRS - pfam02174	Swiss-Prot Protein: O14654 Identical to: NP_003595 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PH	cd00821	0.00039	81	197
PTB_IRS	cd01204	6.9e-63	231	334
	cd00824	5.5e-36	232	334
PH	pfam00169	0.00084	79	199
IRS	pfam02174	4.5e-46	232	333
PH	smart00233	6.3e-06	79	199
PTBI	smart00310	1.7e-58	232	333

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_038042	Polymorphism	p.ALA20VAL	N/A
dbSNP	rs41307415	Polymorphism	p.ARG411GLN	N/A
dbSNP	rs34287560	Polymorphism	p.ASN508LYS	N/A
Swiss-Prot	VAR_061669	Polymorphism	p.ASP1230TYR	N/A
Swiss-Prot	VAR_038044	Polymorphism	p.GLY557ARG	N/A
Swiss-Prot	VAR_038043	Polymorphism	p.GLY215GLU	N/A
Swiss-Prot	VAR_051080	Polymorphism	p.HIS879ASP	N/A
dbSNP	rs1801164	Polymorphism	p.HIS879TYR	N/A
dbSNP	rs1801162	Polymorphism	p.LEU34PHE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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