Results for the protein: O00141

Results for the Protein: O00141

90185131

6446

SGK1

NCBI, UniProt

SGK1_HUMAN RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1

			0 2 0 0 2

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Swiss-Prot Protein: O00141

Identical to: NP_005618

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK1	cd05622	4.7e-33	40	426
STKc_ROCK2	cd05621	9.5e-28	54	425
STKc_PAK_I	cd06647	3.7e-17	65	370
STKc_PAK2	cd06655	2.9e-10	65	379
STKc_PAK3	cd06656	2.1e-10	65	378
STKc_JNK1	cd07875	4.3e-05	71	430
STKc_JNK2	cd07876	1.5e-05	74	428
STKc_p38alpha_MAPK14	cd07877	2.6e-05	76	423
STKc_TAO1	cd06635	4.1e-06	77	374
STKc_myosinIIIA	cd06638	2.2e-09	77	355
STKc_MAP4K4_6	cd06636	1.1e-06	78	347
STKc_PAK1	cd06654	1.7e-10	78	374
STKc_PAK4	cd06657	1.9e-08	78	368
STKc_PAK5	cd06658	9.4e-09	78	372
STKc_PAK6	cd06659	9.8e-12	78	371
STKc_JNK3	cd07874	0.00023	78	428
STKc_TAO2	cd06634	3.5e-07	79	375
STKc_myosinIIIB	cd06639	1.5e-08	79	350
STKc_JNK	cd07850	8.9e-07	79	419
STKc_TAO3	cd06633	3.7e-05	80	374
STKc_p38beta_MAPK11	cd07878	0.00012	80	423
STKc_p38gamma_MAPK12	cd07880	5.3e-06	80	423
PTKc_FGFR2	cd05101	0.00013	82	361
STKc_PAK	cd06614	3.3e-19	82	358
PKc_MKK7	cd06618	5.9e-10	82	366
STKc_PAK_II	cd06648	1.6e-13	82	368
STKc_p38	cd07851	2.7e-08	82	387
STKc_Sty1_Hog1	cd07856	1.5e-07	85	372
STKc_TAO	cd06607	1.8e-06	86	374
PTKc_FGFR4	cd05099	0.0003	87	375
STKc_MAP4K3	cd06645	8.5e-10	87	354
STKc_myosinIII_like	cd06608	3.1e-13	88	355
STKc_MAP4K5	cd06646	4.4e-08	88	354
STKc_ASK	cd06624	1.2e-16	89	347
PTKc_Tie2	cd05088	8.8e-07	90	379
STKc_STK10_LOK	cd06644	3.7e-12	90	353
PTKc_ALK_LTK	cd05036	7.2e-06	91	333
STKc_MST1_2	cd06612	2.6e-15	91	329
STKc_CDK10	cd07845	2.4e-09	91	374
PTK_CCK4	cd05046	0.00017	92	342
PTKc_Ror	cd05048	4.6e-05	92	343
PTKc_Trk	cd05049	1.5e-06	92	351
PTKc_Musk	cd05050	8.6e-06	92	351
PTKc_Abl	cd05052	4e-08	92	353
PTKc_FAK	cd05056	1.3e-07	92	363
PTKc_InsR	cd05061	0.00059	92	355
PTKc_EphR_A2	cd05063	6.6e-06	92	354
PTKc_EphR_A10	cd05064	4.3e-05	92	357
PTKc_Frk_like	cd05068	2.2e-07	92	352
PTKc_Yes	cd05069	0.00028	92	350
PTKc_Fyn_Yrk	cd05070	0.00033	92	350
PTKc_Src	cd05071	0.00031	92	356
PTKc_Lyn	cd05072	4.2e-06	92	353
PTKc_Hck	cd05073	3.9e-05	92	354
PTKc_Lck_Blk	cd05067	4.9e-05	92	382
PTKc_Csk	cd05082	7.6e-06	92	334
PTKc_Ror2	cd05091	0.00027	92	352
PTKc_TrkA	cd05092	1.2e-05	92	359
PTKc_TrkB	cd05093	4.1e-06	92	361
STKc_TNIK	cd06637	3.2e-07	92	355
PKc_MEK2	cd06649	5.3e-06	92	429
PKc_MEK1	cd06650	6.3e-05	92	431
STKc_PCTAIRE_like	cd07844	7.7e-14	92	385
STKc_MAPK4_6	cd07854	5.7e-06	92	373
STKc_ERK5	cd07855	1.1e-06	92	401
STKc_TEY_MAPK_plant	cd07858	1.3e-06	92	425
STKc_CDK12	cd07864	2.9e-07	92	347
STKc_PFTAIRE1	cd07869	1.7e-05	92	403
STKc_PFTAIRE2	cd07870	5.9e-08	92	385
STKc_PCTAIRE3	cd07871	3.4e-08	92	355
STKc_PCTAIRE1	cd07873	4.2e-06	92	362
STKc_PCTAIRE2	cd07872	1.3e-06	92	375
PTKc_EphR	cd05033	3.9e-05	93	358
PTKc_EGFR_like	cd05057	2.2e-06	93	350
PTKc_EphR_B	cd05065	3.7e-06	93	353
PTKc_EphR_A	cd05066	2e-05	93	358
PTK_HER3	cd05111	7e-06	93	350
PTKc_Btk_Bmx	cd05113	4.9e-09	93	350
PTKc_Tec_Rlk	cd05114	1.6e-08	93	354
PTKc_Itk	cd05112	2.7e-08	93	354
STKc_SLK_like	cd06611	7.4e-13	93	366
STKc_SLK	cd06643	1.9e-11	93	373
PTKc_InsR_like	cd05032	5e-06	94	351
PTKc_Chk	cd05083	5.3e-05	94	352
PTKc_HER2	cd05109	1.3e-05	94	359
PTKc_HER4	cd05110	3.7e-05	94	393
PTKc_EGFR	cd05108	5.2e-05	94	408
STKc_MAP4K3_like	cd06613	1.5e-15	94	346
PKc_MKK4	cd06616	8.6e-10	94	369
PKc_MAPKK_Byr1_like	cd06620	2.3e-09	94	386
STKc_MST4	cd06640	5.9e-09	94	368
STKc_MST3	cd06641	1.8e-08	94	367
STKc_STK25-YSK1	cd06642	2.3e-09	94	361
STKc_CDK9	cd07865	6.3e-07	94	355
STKc_BUR1	cd07866	6e-09	94	355
PTKc_Csk_like	cd05039	1.6e-06	95	309
PTKc_Tec_like	cd05059	7.9e-07	95	332
PTKc_DDR2	cd05095	0.00075	95	355
STKc_MEKK3_like	cd06625	4.7e-16	95	355
STKc_MEKK3	cd06651	5.1e-11	95	357
STKc_MEKK2	cd06652	1.4e-07	95	352
STKc_MEKK3_like_1	cd06653	1.7e-09	95	355
STKc_ERK1_2_like	cd07849	1.3e-07	95	416
PTKc_Src_like	cd05034	5.4e-07	96	346
PTKc_Jak_rpt2	cd05038	3.3e-07	96	365
PTKc_Tie1	cd05089	1.2e-05	96	380
PTKc_Ror1	cd05090	0.0001	96	352
PTKc_Srm_Brk	cd05148	9.2e-07	96	323
STKc_ROCK_NDR_like	cd05573	5.2e-89	96	424
STKc_phototropin_lik	cd05574	1.1e-80	96	381
STKc_PKA	cd05580	1.3e-138	96	388
STKc_PDK1	cd05581	7.2e-79	96	355
STKc_DMPK_like	cd05597	4.3e-68	96	424
STKc_LATS	cd05598	7.9e-52	96	431
STKc_Sid2p_Dbf2p	cd05600	1.8e-23	96	425
STKc_CRIK	cd05601	3.1e-40	96	424
STKc_NDR_like	cd05599	7.2e-27	96	427
STKc_MAST	cd05609	2.2e-60	96	386
STKc_PRKX_like	cd05612	6.8e-110	96	387
STKc_MRCK_alpha	cd05623	4.2e-53	96	425
STKc_MRCK_beta	cd05624	2.4e-56	96	424
STKc_LATS2	cd05626	8.1e-40	96	427
STKc_NDR2	cd05627	1.3e-34	96	427
STKc_NDR1	cd05628	1.7e-34	96	427
STKc_NDR_like_fungal	cd05629	4.2e-48	96	427
STKc_LATS1	cd05625	5.9e-32	96	427
PKc_MAPKK	cd06605	1.9e-14	96	360
STKc_OSR1_SPAK	cd06610	1.9e-14	96	355
PKc_MEK	cd06615	3.2e-10	96	368
PKc_MKK3_6	cd06617	1.6e-09	96	374
PKc_MKK5	cd06619	8.9e-06	96	367
PKc_MAPKK_Pek1_like	cd06621	1e-09	96	354
PKc_MAPKK_PBS2_like	cd06622	9.2e-08	96	414
STKc_MST3_like	cd06609	5.5e-14	96	368
PKc_MAPKK_plant_like	cd06623	1.8e-17	96	351
STKc_NAK1_like	cd06917	3.9e-12	96	368
STKc_CdkB_plant	cd07837	1.4e-09	96	356
STKc_CDC2L1	cd07843	1.8e-06	96	347
STKc_CDKL2_3	cd07846	3.1e-09	96	385
STKc_CDKL1_4	cd07847	1.2e-09	96	385
STKc_CDKL5	cd07848	1.9e-06	96	389
STKc_CDK6	cd07862	4.1e-05	96	381
STKc_Nek6_Nek7	cd08224	8.4e-11	96	355
STKc_Nek6	cd08228	4.2e-09	96	349
STKc_Nek7	cd08229	1.1e-11	96	353
SPS1	COG0515	3.4e-64	96	431
PTKc_RET	cd05045	5.8e-05	97	335
PTKc_Jak1_rpt2	cd05079	0.00021	97	383
PKc_STE	cd05122	7.8e-32	97	346
STKc_Yank1	cd05578	2.4e-79	97	355
STKc_MSK_N	cd05583	7e-102	97	374
STKc_cPKC	cd05587	5.2e-115	97	425
STKc_GRK4_like	cd05605	2.6e-65	97	376
STKc_MSK1_N	cd05613	2.5e-79	97	374
STKc_MSK2_N	cd05614	1.5e-91	97	426
STKc_cPKC_alpha	cd05615	7.5e-101	97	425
STKc_cPKC_beta	cd05616	3.8e-101	97	425
STKc_GRK6	cd05630	1.2e-54	97	376
STKc_GRK4	cd05631	2.9e-52	97	376
STKc_GRK5	cd05632	2.9e-53	97	376
STKc_MAPKKK	cd06606	1.1e-28	97	355
STKc_Cdc7_like	cd06627	1.4e-19	97	355
STKc_CCRK	cd07832	1.1e-14	97	356
STKc_MAPK	cd07834	2.7e-09	97	401
STKc_Pho85	cd07836	7.4e-09	97	389
STKc_CDK5	cd07839	4e-07	97	355
STKc_CDK7	cd07841	3.2e-10	97	350
STKc_CDK8_like	cd07842	4.7e-08	97	355
STKc_NLK	cd07853	1e-05	97	421
STKc_MPK1	cd07857	1.5e-07	97	393
STKc_TDY_MAPK_plant	cd07859	1.1e-07	97	425
STKc_CDK2_3	cd07860	1.3e-06	97	355
STKc_CDK1_euk	cd07861	8.6e-07	97	389
STKc_CDK4	cd07863	1e-06	97	355
STKc_CDC2L6	cd07867	0.00098	97	389
STKc_Nek	cd08215	6.7e-43	97	351
STKc_Nek2	cd08217	1e-16	97	347
STKc_Nek1	cd08218	1e-26	97	347
STKc_Nek3	cd08219	2e-22	97	353
STKc_Nek8	cd08220	8.9e-20	97	355
STKc_Nek11	cd08222	1.1e-13	97	347
STKc_Nek4	cd08223	8.4e-26	97	355
STKc_Nek5	cd08225	1.4e-29	97	347
STKc_Nek10	cd08528	2.6e-16	97	355
STKc_FA2-like	cd08529	5.6e-13	97	332
STKc_CNK2-like	cd08530	6.8e-14	97	352
PTKc_Axl_like	cd05035	3e-06	98	350
PTKc_Tyro3	cd05074	3.1e-05	98	353
PTKc_Axl	cd05075	0.00048	98	353
PTKc_Jak2_Jak3_rpt2	cd05081	8.4e-07	98	383
PTKc_Tyk2_rpt2	cd05080	7.7e-05	98	384
STKc_CMGC	cd05118	9.2e-16	98	355
STKc_PKN	cd05589	2.7e-125	98	424
STKc_MAPKKK_Bck1_lik	cd06629	1.7e-12	98	355
STKc_CDK_like	cd07829	3.1e-15	98	355
STKc_MOK	cd07831	5.8e-11	98	355
STKc_CDKL	cd07833	1.9e-11	98	355
STKc_CDK1_like	cd07835	6.5e-08	98	385
STKc_MAK_like	cd07830	2.4e-14	98	355
STKc_CDK4_6_like	cd07838	7.5e-12	98	355
STKc_CDK9_like	cd07840	1.2e-12	98	355
STKc_MAPKKK_Byr2_lik	cd06628	9e-24	99	355
STKc_MEKK1	cd06630	7.6e-09	99	356
PK_STRAD	cd08216	0.00026	99	366
STKc_Nek9	cd08221	7.6e-11	99	351
STKc_RSK_N	cd05582	2.8e-105	101	424
STKc_p70S6K	cd05584	6.3e-121	101	426
STKc_Rim15_like	cd05611	1.4e-20	101	361
STKc_MEKK4	cd06626	1.4e-12	101	347
PTKc	cd00192	6.3e-11	102	350
PTKc_Ack_like	cd05040	1.5e-08	102	348
PTKc_Fes_like	cd05041	8.5e-08	102	351
PTKc_c-ros	cd05044	0.00017	102	355
PTKc_Tie	cd05047	2.5e-05	102	358
PTKc_Met_Ron	cd05058	7.9e-05	102	359
PTK_Jak1_rpt1	cd05077	0.00044	102	350
PTKc_Syk_like	cd05060	3.5e-06	102	329
PTKc_Fes	cd05084	2.4e-07	102	351
PTKc_Fer	cd05085	3.5e-06	102	355
PTKc_Aatyk	cd05042	0.00043	102	352
PTKc_Syk	cd05116	1.8e-05	102	354
STKc_PKC	cd05570	4.1e-131	102	424
STKc_PKB	cd05571	1.8e-137	102	426
STKc_SGK	cd05575	5.2e-277	102	424
STKc_aPKC	cd05588	1.6e-106	102	425
STKc_nPKC_eta	cd05590	4.3e-112	102	425
STKc_nPKC_epsilon	cd05591	1.1e-115	102	425
STKc_nPKC_theta_delt	cd05592	1.4e-108	102	426
STKc_PKB_gamma	cd05593	8.2e-119	102	429
STKc_PKB_alpha	cd05594	1.1e-119	102	427
STKc_PKB_beta	cd05595	4.1e-124	102	426
STKc_SGK1	cd05602	6e-300	102	426
STKc_SGK2	cd05603	8.6e-231	102	425
STKc_SGK3	cd05604	4.4e-225	102	426
STKc_aPKC_zeta	cd05617	1e-95	102	425
STKc_aPKC_iota	cd05618	5.4e-90	102	425
STKc_nPKC_theta	cd05619	5.2e-95	102	426
STKc_nPKC_delta	cd05620	2.4e-91	102	426
STKc_YSK4	cd06631	1.1e-10	102	355
STKc_MEKK1_plant	cd06632	1.4e-14	102	355
STKc_beta_ARK	cd05606	1.2e-61	103	375
STKc_GRK3	cd05633	7.2e-55	103	376
PKc	cd00180	8.1e-75	104	350
PTKc_Zap-70	cd05115	1.2e-05	104	354
STKc_AGC	cd05123	8.1e-162	104	355
STKc_cGK_PKG	cd05572	1.1e-77	104	362
STKc_GRK	cd05577	1.5e-70	104	375
STKc_MAST_like	cd05579	4.1e-65	104	360
STKc_YPK1_like	cd05585	1.5e-128	104	423
STKc_Sck1_like	cd05586	2.8e-107	104	423
STKc_GRK7	cd05607	2.7e-53	104	375
STKc_GRK1	cd05608	3.2e-68	104	375
STKc_MAPK15	cd07852	3.1e-07	127	368
Pkinase	pfam00069	8.4e-89	98	355
Pkinase_C	pfam00433	2e-11	375	427
Pkinase_Tyr	pfam07714	2.9e-15	98	353
TyrKc	smart00219	1.2e-12	98	355
STYKc	smart00221	4.3e-96	98	355
S_TKc	smart00220	5.9e-108	108	355
KIND	smart00750	1.2e-06	188	363
S_TK_X	smart00133	1.1e-21	356	425

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041072	Polymorphism	p.ALA342VAL	N/A
Swiss-Prot	VAR_041071	Polymorphism	p.VAL219ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258