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  Domain Name: 2-oxoacid_dh
2-oxoacid dehydrogenases acyltransferase (catalytic domain). These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain.
No pairwise interactions found for the domain 2-oxoacid_dh

Total Mutations Found: 6
Total Disease Mutations Found: 4
This domain occurred 3 times on human genes (3 proteins).



  MAPLE SYRUP URINE DISEASE, INTERMEDIATE, TYPE II
  MAPLE SYRUP URINE DISEASE, THIAMINE-RESPONSIVE, TYPE II
  PYRUVATE DEHYDROGENASE E2 DEFICIENCY


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for 2-oxoacid_dh











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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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