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  Domain Name: 7TM_GPCR_Srsx
Serpentine type 7TM GPCR chemoreceptor Srsx. Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srsx is a solo family amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
No pairwise interactions found for the domain 7TM_GPCR_Srsx

Total Mutations Found: 125
Total Disease Mutations Found: 29
This domain occurred 74 times on human genes (155 proteins).



  BETA-2-ADRENORECEPTOR AGONIST, REDUCED RESPONSE TO
  DIABETES MELLITUS, TYPE 2, SUSCEPTIBILITY TO
  GLUCOCORTICOID DEFICIENCY 1
  MYOCLONUS-DYSTONIA SYNDROME
  OBESITY
  OBESITY, SUSCEPTIBILITY TO
  SOMATOSTATIN ANALOG, RESISTANCE TO


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for 7TM_GPCR_Srsx












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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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