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  Domain Name: ANK
ankyrin repeats. Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.

Total Mutations Found: 61
Total Disease Mutations Found: 9
This domain occurred 221 times on human genes (420 proteins).



  CEREBRAL CAVERNOUS MALFORMATIONS 1
  DOPAMINE RECEPTOR D2, REDUCED BRAIN DENSITY OF
  GLAUCOMA 1, OPEN ANGLE, F
  LEFT VENTRICULAR NONCOMPACTION 7
  NEPHRONOPHTHISIS 2
  PARKINSON DISEASE 14
  USHER SYNDROME, TYPE IG


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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for ANK






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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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