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  Domain Name: C1Q
Complement component C1q domain. Globular domain found in many collagens and eponymously in complement C1q. When part of full length proteins these domains form a 'bouquet' due to the multimerization of heterotrimers. The C1q fold is similar to that of tumour necrosis factor.
No pairwise interactions found for the domain C1Q

Total Mutations Found: 30
Total Disease Mutations Found: 16
This domain occurred 31 times on human genes (50 proteins).



  ADIPONECTIN DEFICIENCY
  C1Q DEFICIENCY
  METAPHYSEAL CHONDRODYSPLASIA, SCHMID TYPE
  RETINAL DEGENERATION, LATE-ONSET, AUTOSOMAL DOMINANT


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   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for C1Q








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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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