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  Domain Name: CNX
Connexin homologues. Connexin channels participate in the regulation of signaling between developing and differentiated cell types.
No pairwise interactions found for the domain CNX

Total Mutations Found: 21
Total Disease Mutations Found: 19
This domain occurred 20 times on human genes (36 proteins).



  ATRIAL FIBRILLATION, FAMILIAL, 11
  CATARACT 1 WITH MICROCORNEA
  CATARACT 1, MULTIPLE TYPES
  CATARACT 1, ZONULAR PULVERULENT
  CATARACT 14, ZONULAR PULVERULENT
  CHARCOT-MARIE-TOOTH DISEASE, X-LINKED DOMINANT, 1
  DEAFNESS, AUTOSOMAL DOMINANT 3A
  DEAFNESS, AUTOSOMAL RECESSIVE 1A
  DEAFNESS, AUTOSOMAL RECESSIVE 1A, INCLUDED
  HYSTRIX-LIKE ICHTHYOSIS WITH DEAFNESS, INCLUDED
  KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME, AUTOSOMAL DOMINANT
  KERATODERMA, PALMOPLANTAR, WITH DEAFNESS
  KNUCKLE PADS, LEUKONYCHIA, AND SENSORINEURAL DEAFNESS
  LYMPHEDEMA, HEREDITARY, IC
  VOHWINKEL SYNDROME


Tips:
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 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for CNX





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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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