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  Domain Name: CY
Cystatin-like domain. Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.
No pairwise interactions found for the domain CY

Total Mutations Found: 35
Total Disease Mutations Found: 8
This domain occurred 16 times on human genes (26 proteins).



  EXFOLIATIVE ICHTHYOSIS, AUTOSOMAL RECESSIVE, ICHTHYOSIS BULLOSA OF
  KININOGEN DEFICIENCY, TOTAL
  LEANNESS, SUSCEPTIBILITY TO
  MYCLONIC EPILEPSY OF UNVERRICHT AND LUNDBORG
  MYOCLONIC EPILEPSY OF UNVERRICHT AND LUNDBORG
  SIEMENS-LIKE
  THROMBOPHILIA DUE TO HISTIDINE-RICH GLYCOPROTEIN DEFICIENCY


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for CY







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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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