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  Domain Name: DEAD_2
DEAD_2. This represents a conserved region within a number of RAD3-like DNA-binding helicases that are seemingly ubiquitous - members include proteins of eukaryotic, bacterial and archaeal origin. RAD3 is involved in nucleotide excision repair, and forms part of the transcription factor TFIIH in yeast.
No pairwise interactions found for the domain DEAD_2

Total Mutations Found: 8
Total Disease Mutations Found: 5
This domain occurred 6 times on human genes (12 proteins).



  BREAST CANCER, EARLY-ONSET
  FANCONI ANEMIA, COMPLEMENTATION GROUP J
  TRICHOTHIODYSTROPHY
  WARSAW BREAKAGE SYNDROME
  XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP D, INCLUDED


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for DEAD_2









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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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