Home News About DMDM Database Statistics Research Publications Contact  

 
  Domain Name: DUF3451
Domain of unknown function (DUF3451). This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 199 to 238 amino acids in length. This domain is found associated with pfam06512, pfam00520. This domain has a conserved ADD sequence motif.
No pairwise interactions found for the domain DUF3451

Total Mutations Found: 40
Total Disease Mutations Found: 8
This domain occurred 6 times on human genes (22 proteins).



  ATRIAL FIBRILLATION, FAMILIAL, 10
  CARDIAC CONDUCTION DEFECT, NONPROGRESSIVE
  GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 7
  NEUROPATHY, SMALL FIBER
  PROGRESSIVE FAMILIAL HEART BLOCK, TYPE IA


Tips:
 If you've navigated here from a protein, hovering over a position on the weblogo will display the corresponding protein position for that domain position.

 The histograms below the weblogo indicate mutations found on the domain. Red is for disease (OMIM) and blue is for SNPs.

 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for DUF3451













Weblogos are Copyright (c) 2002 Regents of the University of California




Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258