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  Domain Name: FabG
Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]
No pairwise interactions found for the domain FabG

Total Mutations Found: 119
Total Disease Mutations Found: 63
This domain occurred 53 times on human genes (88 proteins).



  17-@BETA HYDROXYSTEROID DEHYDROGENASE III DEFICIENCY
  17-@BETA-HYDROXYSTEROID DEHYDROGENASE X DEFICIENCY
  2-METHYL-3-HYDROXYBUTYRYL-COA DEHYDROGENASE DEFICIENCY (MHBD DEFICIENCY)
  APPARENT MINERALOCORTICOID EXCESS
  APPARENT MINERALOCORTICOID EXCESS, MILD
  CORTISONE REDUCTASE DEFICIENCY 2
  CRANIOOSTEOARTHROPATHY
  D-BIFUNCTIONAL PROTEIN DEFICIENCY
  D-BIFUNCTIONAL PROTEIN DEFICIENCY (DBPD)
  DIGITAL CLUBBING, ISOLATED CONGENITAL
  DYSTONIA, DOPA-RESPONSIVE, DUE TO SEPIAPTERIN REDUCTASE DEFICIENCY
  ESOPHAGEAL SQUAMOUS CELL CARCINOMA, SOMATIC
  FUNDUS ALBIPUNCTATUS, AUTOSOMAL RECESSIVE
  HYPERPHENYLALANINEMIA, BH4-DEFICIENT, C
  HYPERPHENYLALANINEMIA, BH4-DEFICIENT, C (HPABH4C)
  LEBER CONGENITAL AMAUROSIS 13
  MENTAL RETARDATION, X-LINKED, SYNDROMIC 10
  PERRAULT SYNDROME 1
  PERRAULT SYNDROME 1 (PRLTS1)
  RETINITIS PIGMENTOSA 53


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for FabG























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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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