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  Domain Name: Glycogen_syn
Glycogen synthase. This family consists of the eukaryotic glycogen synthase proteins GYS1, GYS2 and GYS3. Glycogen synthase (GS) is the enzyme responsible for the synthesis of -1,4-linked glucose chains in glycogen. It is the rate limiting enzyme in the synthesis of the polysaccharide, and its activity is highly regulated through phosphorylation at multiple sites and also by allosteric effectors, mainly glucose 6-phosphate (G6P).
No pairwise interactions found for the domain Glycogen_syn

Total Mutations Found: 14
Total Disease Mutations Found: 9
This domain occurred 2 times on human genes (4 proteins).



  GLYCOGEN STORAGE DISEASE 0, LIVER
  GLYCOGEN STORAGE DISEASE 0, MUSCLE


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Glycogen_syn























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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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