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  Domain Name: HATPase_c
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 17
Total Disease Mutations Found: 13
This domain occurred 21 times on human genes (46 proteins).



  COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2
  COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2, INCLUDED
  COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 4, INCLUDED
  COLORECTAL CANCER, SPORADIC, SUSCEPTIBILITY TO
  HEREDITARY NON-POLYPOSIS COLORECTAL CANCER 7 (HNPCC7)
  MISMATCH REPAIR CANCER SYNDROME
  MISMATCH REPAIR CANCER SYNDROME, INCLUDED
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


Feature Name:Total Found:
ATP binding site
Mg2+ binding site
G-X-G motif













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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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