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  Domain Name: LIM
Zinc-binding domain present in Lin-11, Isl-1, Mec-3. Zinc-binding domain family. Some LIM domains bind protein partners via tyrosine-containing motifs. LIM domains are found in many key regulators of developmental pathways.

Total Mutations Found: 85
Total Disease Mutations Found: 33
This domain occurred 70 times on human genes (172 proteins).



  CARDIOMYOPATHY, DILATED, 1C
  CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 12
  EPILEPSY, PROGRESSIVE MYOCLONIC 1B
  EPILEPSY, PROGRESSIVE MYOCLONIC 5
  LEFT VENTRICULAR NONCOMPACTION 3, INCLUDED
  MYOPATHY, REDUCING BODY, X-LINKED, CHILDHOOD-ONSET
  MYOPATHY, REDUCING BODY, X-LINKED, SEVERE EARLY-ONSET
  MYOPATHY, X-LINKED, WITH POSTURAL MUSCLE ATROPHY
  NAIL-PATELLA SYNDROME
  PITUITARY HORMONE DEFICIENCY, COMBINED, 3
  SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT


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 Functional Features are displayed as orange boxes under the histograms. You can choose which features are displayed in the box below.



Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for LIM






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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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