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  Domain Name: MdlB
ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]
No pairwise interactions found for the domain MdlB

Total Mutations Found: 395
Total Disease Mutations Found: 222
This domain occurred 37 times on human genes (77 proteins).



  ADDISON DISEASE
  ADRENOLEUKODYSTROPHY
  ADRENOMYELONEUROPATHY
  ANEMIA, SIDEROBLASTIC, AND SPINOCEREBELLAR ATAXIA
  APOCRINE GLAND SECRETION, VARIATION IN
  ARTERIAL CALCIFICATION, GENERALIZED, OF INFANCY, 2
  ARTERIAL CALCIFICATION, GENERALIZED, OF INFANCY, 2, INCLUDED
  ATRIAL FIBRILLATION, FAMILIAL, 12
  AXILLARY ODOR, INCLUDED;;
  CARDIOMYOPATHY, DILATED, 1O
  CHOLESTASIS, BENIGN RECURRENT INTRAHEPATIC 2
  CHOLESTASIS, BENIGN RECURRENT INTRAHEPATIC 2, INCLUDED
  CHOLESTASIS, BENIGN RECURRENT INTRAHEPATIC, 2 (BRIC2)
  CHOLESTASIS, INTRAHEPATIC, OF PREGNANCY, 3
  CHOLESTASIS, INTRAHEPATIC, OF PREGNANCY, 3, INCLUDED
  CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC 2
  CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC 3
  CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC, 2 (PFIC2)
  COLCHICINE RESISTANCE
  COLOSTRUM SECRETION, IN
  CONE-ROD DYSTROPHY 3, INCLUDED
  CONGENITAL BILATERAL ABSENCE OF THE VAS DEFERENS (CBAVD)
  CYSTIC FIBROSIS
  CYSTIC FIBROSIS (CF)
  DUBIN-JOHNSON SYNDROME
  DYSCHROMATOSIS UNIVERSALIS HEREDITARIA 3
  EAR WAX, WET/DRY, INCLUDED;;
  GALLBLADDER DISEASE 1
  GALLBLADDER DISEASE 1 (GBD1)
  GALLBLADDER DISEASE 1, INCLUDED
  HIGH DENSITY LIPOPROTEIN DEFICIENCY
  HYPERTRICHOTIC OSTEOCHONDRODYSPLASIA
  HYPERTRYPSINEMIA, NEONATAL, SUSCEPTIBILITY TO, INCLUDED
  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 4A
  ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 4B
  LANGEREIS BLOOD GROUP SYSTEM, LAN(-) PHENOTYPE
  MACULAR DEGENERATION, AGE-RELATED, 2, SUSCEPTIBILITY TO
  METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA, CBLJ TYPE
  MICROPHTHALMIA, ISOLATED, WITH COLOBOMA 7
  PANCREATITIS, IDIOPATHIC, SUSCEPTIBILITY TO
  PSEUDOXANTHOMA ELASTICUM
  PSEUDOXANTHOMA ELASTICUM, INCLUDED
  STARGARDT DISEASE 1
  SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 3
  TANGIER DISEASE
  TAP1 DEFICIENCY, SOMATIC
  VAS DEFERENS, CONGENITAL BILATERAL ABSENCE OF
  VAS DEFERENS, CONGENITAL BILATERAL ABSENCE OF, INCLUDED


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for MdlB