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  Domain Name: RNase_H2-Ydr279
Ydr279p protein family (RNase H2 complex component). RNases H are enzymes that specifically hydrolyse RNA when annealed to a complementary DNA and are present in all living organisms. In yeast RNase H2 is composed of a complex of three proteins (Rnh2Ap, Ydr279p and Ylr154p), this family represents the homologues of Ydr279p. It is not known whether non yeast proteins in this family fulfil the same function.
No pairwise interactions found for the domain RNase_H2-Ydr279

Total Mutations Found: 4
Total Disease Mutations Found: 2
This domain occurred 1 times on human genes (3 proteins).



  AICARDI-GOUTIERES SYNDROME 2


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for RNase_H2-Ydr279






















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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