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  Domain Name: Sema
Sema domain. The Sema domain occurs in semaphorins, which are a large family of secreted and transmembrane proteins, some of which function as repellent signals during axon guidance. Sema domains also occur in the hepatocyte growth factor receptor and human plexin A-3.

Total Mutations Found: 35
Total Disease Mutations Found: 9
This domain occurred 24 times on human genes (42 proteins).



  CONE-ROD DYSTROPHY 10, INCLUDED
  HEPATOCELLULAR CARCINOMA (HCC)
  RENAL CELL CARCINOMA PAPILLARY (RCCP)
  RETINITIS PIGMENTOSA 35


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Sema



















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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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