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  Domain Name: Sox_C_TAD
Sox C-terminal transactivation domain. This domain is found at the C-terminus of the Sox family of transcription factors. It is found associated with pfam00505. It binds to the Armadillo repeats (pfam00514) in Catenin beta-1 (CTNNB1), which is involved in transcriptional regulation. It functions as a transactivating domain (TAD).
No pairwise interactions found for the domain Sox_C_TAD

Total Mutations Found: 2
Total Disease Mutations Found: 2
This domain occurred 3 times on human genes (5 proteins).



  HYPOTRICHOSIS-LYMPHEDEMA-TELANGIECTASIA SYNDROME
  VESICOURETERAL REFLUX 3


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


No Conserved Features/Sites Found for Sox_C_TAD












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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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