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  Domain Name: ZnMc_adamalysin_II_l
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions.
No pairwise interactions are available for this conserved domain.

Total Mutations Found: 38
Total Disease Mutations Found: 8
This domain occurred 37 times on human genes (74 proteins).



  CONE-ROD DYSTROPHY 9
  THROMBOTIC THROMBOCYTOPENIC PURPURA, CONGENITAL
  WEILL-MARCHESANI SYNDROME 1
  WEILL-MARCHESANI-LIKE SYNDROME


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Range on the Protein:  

   Protein ID            Protein Position

Domain Position:  


Feature Name:Total Found:
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Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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