Table of Pairwise Domain-Domain Interactions for the domain:
DnaJInteracting Domains ↕ | CD ↕ Accession (External Link) | Description ↕ |
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HSCB_C | pfam07743 | HSCB C-terminal oligomerisation domain. This domain is the HSCB C-terminal oligomerisation domain and is found on co-chaperone proteins. | Rb_C | pfam08934 | Rb C-terminal domain. The Rb C-terminal domain is required for high-affinity binding to E2F-DP complexes and for maximal repression of E2F-responsive promoters, thereby acting as a growth suppressor by blocking the G1-S transition of the cell cycle. This domain has a strand-loop-helix structure, which directly interacts with both E2F1 and DP1, followed by a tail segment that lacks regular secondary structure. |
Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.
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