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Table of Pairwise Domain-Domain Interactions for the domain:

Interacting Domains ↕CD ↕ Accession (External Link)Description ↕
C1-setpfam07654Immunoglobulin C1-set domain.
Lectin_Cpfam00059Lectin C-type domain. This family includes both long and short form C-type
MAGEpfam01454MAGE family. The MAGE (melanoma antigen-encoding gene) family are expressed in a wide variety of tumours but not in normal cells, with the exception of the male germ cells, placenta, and, possibly, cells of the developing embryo. The cellular function of this family is unknown. This family also contains the yeast protein, Nse3. The Nse3 protein is part of the Smc5-6 complex. Nse3 has been demonstrated to be important for meiosis.
MHC_II_alphapfam00993Class II histocompatibility antigen, alpha domain.
MHC_II_betapfam00969Class II histocompatibility antigen, beta domain.
igpfam00047Immunoglobulin domain. Ig: immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, such as, T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, such as, butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond.
V-setpfam07686Immunoglobulin V-set domain. This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.
NADHdhpfam00146NADH dehydrogenase.
Recep_L_domainpfam01030Receptor L domain. The L domains from these receptors make up the bilobal ligand binding site. Each L domain consists of a single-stranded right hand beta-helix. This Pfam entry is missing the first 50 amino acid residues of the domain.
TFR_dimerpfam04253Transferrin receptor-like dimerisation domain. This domain is involved in dimerisation of the transferrin receptor as shown in its crystal structure.
ATP-synt_Apfam00119ATP synthase A chain.
Vps5pfam09325Vps5 C terminal like. Vps5 is a sorting nexin that functions in membrane trafficking. This is the C terminal dimerisation domain.
Pcc1pfam09341Transcription factor Pcc1. Pcc1 is a transcription factor that functions in regulating genes involved in cell cycle progression and polarised growth.

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