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Table of Pairwise Domain-Domain Interactions for the domain:

Interacting Domains ↕CD ↕ Accession (External Link)Description ↕
igpfam00047Immunoglobulin domain. Ig: immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, such as, T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, such as, butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond.
C2-setpfam05790Immunoglobulin C2-set domain.
C1-setpfam07654Immunoglobulin C1-set domain.
MHC_Ipfam00129Class I Histocompatibility antigen, domains alpha 1 and 2.
MHC_II_betapfam00969Class II histocompatibility antigen, beta domain.
MHC_II_alphapfam00993Class II histocompatibility antigen, alpha domain.
C2-set_2pfam08205CD80-like C2-set immunoglobulin domain. These domains belong to the immunoglobulin superfamily.
MAGEpfam01454MAGE family. The MAGE (melanoma antigen-encoding gene) family are expressed in a wide variety of tumours but not in normal cells, with the exception of the male germ cells, placenta, and, possibly, cells of the developing embryo. The cellular function of this family is unknown. This family also contains the yeast protein, Nse3. The Nse3 protein is part of the Smc5-6 complex. Nse3 has been demonstrated to be important for meiosis.

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