Results for the gene: CDK4

Results for Proteins associated with the Gene: CDK4

CDK4

1019

P11802 NP_000066

NCBI

Known Diseases associated with this Protein:

MELANOMA, CUTANEOUS MALIGNANT 3 (CMM3)

MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3

			5 2 2 0 5

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Default View: Pkinase_Tyr - pfam07714 STYKc - smart00221 TyrKc - smart00219 S_TKc - smart00220 KIND - smart00750	Swiss-Prot Protein: P11802 Identical to: NP_000066 Default View:

RefSeq Protein: NP_000066

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000066	PTKc_EphR	cd05033	1	265	8.3e-06
NP_000066	PTKc_ALK_LTK	cd05036	1	267	5.1e-06
NP_000066	PTKc_Ror	cd05048	1	260	8e-09
NP_000066	PTKc_Musk	cd05050	1	267	3.4e-08
NP_000066	PTKc_Abl	cd05052	1	276	1.6e-06
NP_000066	PTKc_FGFR	cd05053	1	232	3.1e-05
NP_000066	PTKc_FAK	cd05056	1	272	3.4e-07
NP_000066	PTKc_EGFR_like	cd05057	1	275	0.0001
NP_000066	PTKc_InsR	cd05061	1	278	6.1e-06
NP_000066	PTKc_IGF-1R	cd05062	1	266	0.00018
NP_000066	PTKc_EphR_B	cd05065	1	268	0.00018
NP_000066	PTKc_Lck_Blk	cd05067	1	287	0.00013
NP_000066	PTKc_Frk_like	cd05068	1	267	3e-07
NP_000066	PTKc_Fyn_Yrk	cd05070	1	267	0.001
NP_000066	PTKc_Lyn	cd05072	1	264	6.5e-05
NP_000066	PTKc_Hck	cd05073	1	264	4.3e-05
NP_000066	PTKc_Chk	cd05083	1	267	0.00014
NP_000066	PTKc_Ror2	cd05091	1	267	2e-05
NP_000066	PTKc_Ror1	cd05090	1	267	1.3e-05
NP_000066	PTKc_Jak1_rpt2	cd05079	1	291	9.6e-06
NP_000066	PTKc_HER2	cd05109	1	291	0.00092
NP_000066	PTKc_Itk	cd05112	1	276	5.9e-07
NP_000066	PTKc_Btk_Bmx	cd05113	1	265	2e-05
NP_000066	PTKc_Tec_Rlk	cd05114	1	265	6.2e-05
NP_000066	PKc_MKK4	cd06616	1	276	6.8e-06
NP_000066	PKc_MKK7	cd06618	1	274	0.00012
NP_000066	PKc_MAPKK_Byr1_like	cd06620	1	288	1.8e-06
NP_000066	STKc_TAO3	cd06633	1	288	0.00012
NP_000066	STKc_MAP4K4_6	cd06636	1	295	0.00014
NP_000066	STKc_PAK_II	cd06648	1	303	9.2e-09
NP_000066	PKc_MEK2	cd06649	1	303	2e-05
NP_000066	PKc_MEK1	cd06650	1	300	0.00031
NP_000066	STKc_PAK2	cd06655	1	302	2.3e-06
NP_000066	STKc_PAK5	cd06658	1	295	0.00013
NP_000066	STKc_PAK6	cd06659	1	303	1.2e-06
NP_000066	STKc_JNK	cd07850	1	303	1e-21
NP_000066	STKc_ERK5	cd07855	1	303	6e-22
NP_000066	STKc_TEY_MAPK_plant	cd07858	1	302	4.3e-42
NP_000066	STKc_CDK12	cd07864	1	295	6.1e-63
NP_000066	STKc_CDK9	cd07865	1	295	1.2e-46
NP_000066	STKc_PCTAIRE2	cd07872	1	303	1.4e-50
NP_000066	STKc_JNK3	cd07874	1	301	1.2e-12
NP_000066	STKc_JNK1	cd07875	1	303	1.1e-10
NP_000066	STKc_JNK2	cd07876	1	303	9.8e-13
NP_000066	STKc_Nek7	cd08229	1	266	3.3e-09
NP_000066	PTK_CCK4	cd05046	2	266	5e-05
NP_000066	PTKc_FGFR1	cd05098	2	292	0.00089
NP_000066	PTKc_FGFR4	cd05099	2	281	0.00042
NP_000066	PTKc_TrkA	cd05092	2	274	3.1e-05
NP_000066	STKc_MAP4K3_like	cd06613	2	294	2e-12
NP_000066	STKc_myosinIII_like	cd06608	2	230	1.7e-08
NP_000066	STKc_ASK	cd06624	2	277	1.2e-09
NP_000066	STKc_TAO2	cd06634	2	289	1.4e-06
NP_000066	STKc_TAO1	cd06635	2	288	6.3e-06
NP_000066	STKc_TNIK	cd06637	2	295	1.3e-05
NP_000066	STKc_myosinIIIB	cd06639	2	296	3.1e-06
NP_000066	STKc_MST4	cd06640	2	298	1.2e-05
NP_000066	STKc_STK25-YSK1	cd06642	2	298	8.3e-07
NP_000066	STKc_SLK	cd06643	2	293	3.1e-06
NP_000066	STKc_STK10_LOK	cd06644	2	300	2.4e-06
NP_000066	STKc_MAP4K3	cd06645	2	294	3.7e-07
NP_000066	STKc_MAP4K5	cd06646	2	294	8.6e-07
NP_000066	STKc_PAK_I	cd06647	2	302	7.9e-06
NP_000066	STKc_PAK1	cd06654	2	301	2e-06
NP_000066	STKc_PAK3	cd06656	2	295	2.9e-06
NP_000066	STKc_MST3	cd06641	2	298	2.6e-06
NP_000066	STKc_myosinIIIA	cd06638	2	295	1.6e-06
NP_000066	STKc_PCTAIRE_like	cd07844	2	295	1.1e-78
NP_000066	STKc_p38	cd07851	2	302	1.1e-21
NP_000066	STKc_Sty1_Hog1	cd07856	2	301	5.9e-36
NP_000066	STKc_BUR1	cd07866	2	295	9.7e-46
NP_000066	STKc_PFTAIRE1	cd07869	2	298	2e-51
NP_000066	STKc_PFTAIRE2	cd07870	2	295	1.9e-61
NP_000066	STKc_PCTAIRE3	cd07871	2	295	1.8e-64
NP_000066	STKc_PCTAIRE1	cd07873	2	303	4.3e-57
NP_000066	STKc_p38alpha_MAPK14	cd07877	2	303	2.3e-12
NP_000066	STKc_p38beta_MAPK11	cd07878	2	303	3.3e-15
NP_000066	STKc_p38delta_MAPK13	cd07879	2	303	3.8e-21
NP_000066	STKc_p38gamma_MAPK12	cd07880	2	303	1.7e-22
NP_000066	STKc_GRK4_like	cd05605	3	302	1.2e-06
NP_000066	STKc_GRK5	cd05632	3	298	0.00036
NP_000066	STKc_SLK_like	cd06611	3	293	9.4e-09
NP_000066	STKc_PAK	cd06614	3	303	1.7e-12
NP_000066	STKc_MEKK2	cd06652	3	278	1.6e-07
NP_000066	STKc_MEKK3_like_1	cd06653	3	273	9.2e-09
NP_000066	STKc_ERK1_2_like	cd07849	3	303	7.9e-27
NP_000066	STKc_MAPK15	cd07852	3	302	6.6e-27
NP_000066	STKc_MAPK4_6	cd07854	3	303	7.7e-25
NP_000066	STKc_Nek6_Nek7	cd08224	3	298	6.4e-10
NP_000066	STKc_Nek6	cd08228	3	273	1.6e-07
NP_000066	PTKc_Jak_rpt2	cd05038	4	296	1.1e-08
NP_000066	PTKc_Srm_Brk	cd05148	4	298	8.6e-07
NP_000066	STKc_ROCK_NDR_like	cd05573	4	297	1.8e-08
NP_000066	STKc_phototropin_lik	cd05574	4	261	5e-07
NP_000066	STKc_PKA	cd05580	4	271	5e-07
NP_000066	STKc_PDK1	cd05581	4	295	7.2e-13
NP_000066	STKc_Sid2p_Dbf2p	cd05600	4	281	0.00019
NP_000066	STKc_MAST	cd05609	4	296	1.1e-07
NP_000066	STKc_PRKX_like	cd05612	4	277	3.2e-07
NP_000066	PKc_MAPKK	cd06605	4	283	1.8e-10
NP_000066	STKc_TAO	cd06607	4	289	5.8e-07
NP_000066	STKc_MST3_like	cd06609	4	272	1.5e-09
NP_000066	STKc_OSR1_SPAK	cd06610	4	295	7.5e-09
NP_000066	PKc_MEK	cd06615	4	302	2.7e-08
NP_000066	PKc_MAPKK_PBS2_like	cd06622	4	293	6.3e-05
NP_000066	PKc_MAPKK_plant_like	cd06623	4	300	2.1e-13
NP_000066	STKc_NAK1_like	cd06917	4	295	4.9e-09
NP_000066	STKc_CdkB_plant	cd07837	4	296	2.3e-95
NP_000066	STKc_CDC2L1	cd07843	4	295	1.5e-71
NP_000066	STKc_CDK10	cd07845	4	302	3.6e-77
NP_000066	STKc_CDKL2_3	cd07846	4	295	2.3e-34
NP_000066	STKc_CDKL1_4	cd07847	4	295	3e-54
NP_000066	STKc_CDKL5	cd07848	4	295	1e-31
NP_000066	STKc_CDK6	cd07862	4	295	2.8e-178
NP_000066	STKc_CDKL	cd07833	4	295	9.1e-42
NP_000066	SPS1	COG0515	4	303	1.3e-29
NP_000066	PTKc_Tyk2_rpt2	cd05080	5	292	2e-05
NP_000066	PKc_STE	cd05122	5	294	9.1e-14
NP_000066	STKc_Yank1	cd05578	5	295	1.3e-12
NP_000066	STKc_MSK_N	cd05583	5	289	0.00021
NP_000066	STKc_MSK1_N	cd05613	5	289	0.0009
NP_000066	STKc_MAPKKK	cd06606	5	295	4.6e-30
NP_000066	STKc_MEKK4	cd06626	5	295	7.7e-11
NP_000066	STKc_Cdc7_like	cd06627	5	295	2.2e-16
NP_000066	STKc_MAPKKK_Byr2_lik	cd06628	5	273	3.4e-18
NP_000066	STKc_CCRK	cd07832	5	296	2.4e-82
NP_000066	STKc_MAPK	cd07834	5	303	3.8e-45
NP_000066	STKc_Pho85	cd07836	5	295	2.7e-85
NP_000066	STKc_CDK5	cd07839	5	295	3.9e-92
NP_000066	STKc_CDK7	cd07841	5	302	3.2e-66
NP_000066	STKc_CDK8_like	cd07842	5	295	3.1e-54
NP_000066	STKc_NLK	cd07853	5	303	1.9e-17
NP_000066	STKc_MPK1	cd07857	5	303	2.7e-18
NP_000066	STKc_TDY_MAPK_plant	cd07859	5	302	7.7e-28
NP_000066	STKc_CDK2_3	cd07860	5	295	1e-98
NP_000066	STKc_CDK1_euk	cd07861	5	295	2.4e-87
NP_000066	STKc_CDK4	cd07863	5	295	3.1e-240
NP_000066	STKc_CDC2L6	cd07867	5	295	3.5e-38
NP_000066	STKc_CDK8	cd07868	5	295	7e-37
NP_000066	STKc_Nek	cd08215	5	295	6.5e-18
NP_000066	STKc_Nek2	cd08217	5	295	5e-12
NP_000066	STKc_Nek1	cd08218	5	295	5.9e-07
NP_000066	STKc_Nek3	cd08219	5	295	1.9e-10
NP_000066	STKc_Nek8	cd08220	5	295	4.2e-08
NP_000066	STKc_Nek9	cd08221	5	295	5.6e-08
NP_000066	STKc_Nek4	cd08223	5	295	6e-06
NP_000066	STKc_Nek5	cd08225	5	264	1.8e-06
NP_000066	STKc_Nek11	cd08222	5	295	6.6e-08
NP_000066	STKc_FA2-like	cd08529	5	295	1.6e-10
NP_000066	STKc_Nek10	cd08528	5	263	8.1e-09
NP_000066	STKc_CNK2-like	cd08530	5	295	4e-11
NP_000066	PTKc_Src_like	cd05034	6	264	1.2e-05
NP_000066	PTKc_Tyro3	cd05074	6	269	0.00023
NP_000066	STKc_CMGC	cd05118	6	295	2.2e-96
NP_000066	STKc_PKN	cd05589	6	293	0.00012
NP_000066	STKc_MST1_2	cd06612	6	295	9.1e-11
NP_000066	STKc_CDK_like	cd07829	6	295	7.3e-154
NP_000066	STKc_MAK_like	cd07830	6	295	5.1e-57
NP_000066	STKc_MOK	cd07831	6	295	7e-41
NP_000066	STKc_CDK1_like	cd07835	6	295	8.3e-93
NP_000066	STKc_CDK4_6_like	cd07838	6	295	6.3e-231
NP_000066	STKc_CDK9_like	cd07840	6	295	5.5e-85
NP_000066	PKc_MKK3_6	cd06617	7	295	7.6e-07
NP_000066	PKc_MAPKK_Pek1_like	cd06621	7	272	3.8e-05
NP_000066	PTKc_Tie2	cd05088	8	283	0.00088
NP_000066	STKc_MEKK3_like	cd06625	8	278	8.7e-14
NP_000066	STKc_MEKK3	cd06651	8	271	6.9e-10
NP_000066	PTKc_Trk	cd05049	9	266	8.3e-08
NP_000066	PTKc_Tec_like	cd05059	9	231	1.8e-06
NP_000066	PTKc_Jak2_Jak3_rpt2	cd05081	9	288	3.9e-07
NP_000066	STKc_RSK_N	cd05582	9	303	0.00091
NP_000066	STKc_p70S6K	cd05584	9	302	0.00051
NP_000066	STKc_Rim15_like	cd05611	9	298	0.00068
NP_000066	PTKc	cd00192	10	291	6.6e-09
NP_000066	PTKc_Csk_like	cd05039	10	245	0.00016
NP_000066	PTKc_Ack_like	cd05040	10	296	3.9e-08
NP_000066	PTKc_Fes_like	cd05041	10	267	2.9e-10
NP_000066	PTKc_Aatyk	cd05042	10	292	8.7e-05
NP_000066	PTKc_Met_Ron	cd05058	10	270	0.00033
NP_000066	PTKc_Syk_like	cd05060	10	232	4.3e-07
NP_000066	PTKc_Fes	cd05084	10	267	6.8e-08
NP_000066	PTKc_Zap-70	cd05115	10	287	0.00051
NP_000066	PTKc_Syk	cd05116	10	270	0.00047
NP_000066	STKc_PKC	cd05570	10	293	0.00018
NP_000066	STKc_SGK2	cd05603	10	296	0.00015
NP_000066	STKc_nPKC_theta	cd05619	10	302	6e-05
NP_000066	STKc_MEKK1	cd06630	10	279	3.3e-10
NP_000066	PKc	cd00180	12	293	5.5e-68
NP_000066	PTKc_Axl_like	cd05035	12	268	0.0001
NP_000066	PTKc_c-ros	cd05044	12	263	6.3e-07
NP_000066	PTKc_Fer	cd05085	12	267	0.00011
NP_000066	STKc_AGC	cd05123	12	296	6.1e-13
NP_000066	STKc_cGK_PKG	cd05572	12	300	6.1e-09
NP_000066	STKc_GRK	cd05577	12	281	2e-06
NP_000066	STKc_MAST_like	cd05579	12	238	5.6e-11
NP_000066	STKc_beta_ARK	cd05606	12	298	2.4e-05
NP_000066	STKc_GRK1	cd05608	12	297	1.4e-05
NP_000066	STKc_GRK7	cd05607	12	267	0.0002
NP_000066	STKc_GRK3	cd05633	12	303	0.00015
NP_000066	STKc_MAPKKK_Bck1_lik	cd06629	12	295	1e-12
NP_000066	STKc_YSK4	cd06631	12	295	1.4e-10
NP_000066	STKc_MEKK1_plant	cd06632	12	295	1.2e-15
NP_000066	Pkinase	pfam00069	6	295	8.4e-81
NP_000066	Pkinase_Tyr	pfam07714	6	295	3e-13
NP_000066	TyrKc	smart00219	6	295	2.5e-11
NP_000066	STYKc	smart00221	6	295	7.9e-84
NP_000066	S_TKc	smart00220	16	295	6.3e-100
NP_000066	KIND	smart00750	116	303	0.00035

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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