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Results for Proteins associated with the Gene: CDK4
CDK4
1019


Known Diseases associated with this Protein:
  MELANOMA, CUTANEOUS MALIGNANT 3 (CMM3)
  MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3
5
2
2
0
5
Tips:
 The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.
 Clicking a check box on the left will display or hide the corresponding domain(s).
 To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.


Default View:

Pkinase_Tyr - pfam07714
STYKc - smart00221
TyrKc - smart00219
S_TKc - smart00220
KIND - smart00750


Swiss-Prot Protein: P11802
Identical to: NP_000066
   Default View:






Default View:

STKc_PAK_II - cd06648
PKc_MEK1 - cd06650
STKc_PAK2 - cd06655
STKc_PAK5 - cd06658
STKc_MAP4K4_6 - cd06636
STKc_TAO3 - cd06633
PTKc_Tec_Rlk - cd05114
PKc_MKK4 - cd06616
PKc_MKK7 - cd06618
PKc_MAPKK_Byr1_like - cd06620
STKc_PAK6 - cd06659
STKc_JNK - cd07850
STKc_JNK1 - cd07875
STKc_JNK2 - cd07876
STKc_Nek7 - cd08229
PTKc_InsR_like - cd05032
STKc_JNK3 - cd07874
STKc_PCTAIRE2 - cd07872
STKc_ERK5 - cd07855
STKc_TEY_MAPK_plant - cd07858
STKc_CDK12 - cd07864
STKc_CDK9 - cd07865
PTKc_Btk_Bmx - cd05113
PKc_MEK2 - cd06649
PTKc_FAK - cd05056
PTKc_EGFR_like - cd05057
PTKc_InsR - cd05061
PTKc_IGF-1R - cd05062
PTKc_FGFR - cd05053
PTKc_Abl - cd05052
PTKc_EphR - cd05033
PTKc_ALK_LTK - cd05036
PTKc_Ror - cd05048
PTKc_Itk - cd05112
PTKc_EphR_B - cd05065
PTKc_Musk - cd05050
PTKc_Ror2 - cd05091
PTKc_Jak1_rpt2 - cd05079
PTKc_Lck_Blk - cd05067
PTKc_HER2 - cd05109
PTKc_Chk - cd05083
PTKc_Ror1 - cd05090
PTKc_Frk_like - cd05068
PTKc_Hck - cd05073
PTKc_Fyn_Yrk - cd05070
PTKc_Lyn - cd05072
STKc_PCTAIRE_like - cd07844
STKc_Sty1_Hog1 - cd07856
STKc_p38 - cd07851
STKc_MST3 - cd06641
STKc_PAK1 - cd06654
STKc_BUR1 - cd07866
STKc_PAK3 - cd06656
STKc_myosinIIIA - cd06638
STKc_p38alpha_MAPK14 - cd07877
STKc_p38delta_MAPK13 - cd07879
STKc_p38gamma_MAPK12 - cd07880
STKc_PAK_I - cd06647
STKc_p38beta_MAPK11 - cd07878
STKc_PCTAIRE1 - cd07873
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE3 - cd07871
STKc_PFTAIRE1 - cd07869
STKc_myosinIII_like - cd06608
PTKc_TrkA - cd05092
STKc_MAP4K3_like - cd06613
STKc_TAO2 - cd06634
PTKc_FGFR4 - cd05099
PTKc_FGFR1 - cd05098
STKc_MAP4K5 - cd06646
PTK_CCK4 - cd05046
STKc_TAO1 - cd06635
STKc_ASK - cd06624
STKc_TNIK - cd06637
STKc_STK10_LOK - cd06644
STKc_MAP4K3 - cd06645
STKc_STK25-YSK1 - cd06642
STKc_SLK - cd06643
STKc_MST4 - cd06640
STKc_myosinIIIB - cd06639
STKc_ERK1_2_like - cd07849
STKc_MAPK15 - cd07852
STKc_Nek6_Nek7 - cd08224
STKc_Nek6 - cd08228
STKc_MAPK4_6 - cd07854
STKc_PAK - cd06614
STKc_GRK4_like - cd05605
STKc_MEKK3_like_1 - cd06653
STKc_GRK5 - cd05632
STKc_SLK_like - cd06611
STKc_MEKK2 - cd06652
STKc_CdkB_plant - cd07837
STKc_CDC2L1 - cd07843
PKc_MAPKK_PBS2_like - cd06622
STKc_CDK10 - cd07845
PKc_MAPKK_plant_like - cd06623
STKc_NAK1_like - cd06917
STKc_CDKL5 - cd07848
SPS1 - COG0515
STKc_CDKL - cd07833
STKc_CDK6 - cd07862
STKc_CDKL1_4 - cd07847
STKc_CDKL2_3 - cd07846
PKc_MEK - cd06615
STKc_phototropin_lik - cd05574
STKc_PKA - cd05580
PTKc_Srm_Brk - cd05148
PTKc_Jak_rpt2 - cd05038
STKc_OSR1_SPAK - cd06610
STKc_PDK1 - cd05581
STKc_ROCK_NDR_like - cd05573
STKc_TAO - cd06607
STKc_Sid2p_Dbf2p - cd05600
PKc_MAPKK - cd06605
STKc_MST3_like - cd06609
STKc_PRKX_like - cd05612
STKc_MAST - cd05609
STKc_Nek - cd08215
STKc_Nek2 - cd08217
STKc_Nek1 - cd08218
STKc_CDK8 - cd07868
STKc_CDK4 - cd07863
STKc_CDK1_euk - cd07861
STKc_Nek3 - cd08219
STKc_CDC2L6 - cd07867
STKc_CNK2-like - cd08530
STKc_FA2-like - cd08529
STKc_Nek10 - cd08528
STKc_CDK2_3 - cd07860
STKc_Nek11 - cd08222
STKc_Nek5 - cd08225
STKc_Nek9 - cd08221
STKc_Nek4 - cd08223
STKc_Nek8 - cd08220
STKc_CDK8_like - cd07842
STKc_MAPKKK - cd06606
STKc_TDY_MAPK_plant - cd07859
STKc_Cdc7_like - cd06627
STKc_MSK1_N - cd05613
STKc_MSK_N - cd05583
PTKc_Tyk2_rpt2 - cd05080
PKc_STE - cd05122
STKc_Yank1 - cd05578
STKc_MAPKKK_Byr2_lik - cd06628
STKc_MEKK4 - cd06626
STKc_CCRK - cd07832
STKc_MPK1 - cd07857
STKc_CDK7 - cd07841
STKc_NLK - cd07853
STKc_MAPK - cd07834
STKc_CDK5 - cd07839
STKc_Pho85 - cd07836
STKc_CDK4_6_like - cd07838
Pkinase - pfam00069
STKc_CDK9_like - cd07840
TyrKc - smart00219
STKc_CDK1_like - cd07835
STYKc - smart00221
Pkinase_Tyr - pfam07714
STKc_MST1_2 - cd06612
PTKc_Src_like - cd05034
PTKc_Tyro3 - cd05074
STKc_PKN - cd05589
STKc_MOK - cd07831
STKc_MAK_like - cd07830
STKc_CDK_like - cd07829
STKc_CMGC - cd05118
PKc_MAPKK_Pek1_like - cd06621
PKc_MKK3_6 - cd06617
STKc_MEKK3_like - cd06625
STKc_MEKK3 - cd06651
PTKc_Tie2 - cd05088
STKc_Rim15_like - cd05611
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Trk - cd05049
STKc_p70S6K - cd05584
PTKc_Tec_like - cd05059
STKc_RSK_N - cd05582
STKc_SGK2 - cd05603
STKc_nPKC_theta - cd05619
STKc_MEKK1 - cd06630
PTKc_Syk - cd05116
STKc_PKC - cd05570
PTKc_Ack_like - cd05040
PTKc_Fes_like - cd05041
PTKc_Zap-70 - cd05115
PTKc - cd00192
PTKc_Csk_like - cd05039
PTKc_Aatyk - cd05042
PTKc_Fes - cd05084
PTKc_Syk_like - cd05060
PTKc_Met_Ron - cd05058
STKc_GRK3 - cd05633
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MEKK1_plant - cd06632
STKc_GRK7 - cd05607
STKc_YSK4 - cd06631
STKc_MAST_like - cd05579
PTKc_c-ros - cd05044
PTKc_Axl_like - cd05035
PKc - cd00180
STKc_GRK1 - cd05608
PTKc_Fer - cd05085
STKc_beta_ARK - cd05606
STKc_AGC - cd05123
STKc_GRK - cd05577
STKc_cGK_PKG - cd05572
S_TKc - smart00220
KIND - smart00750


RefSeq Protein: NP_000066
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Domains found on the Proteins

Protein ↕Domain ↕Domain Accession ↕Start ↕End ↕E-Value ↕
P11802Pkinase_Tyrpfam0771462953e-13
P11802TyrKcsmart0021962952.5e-11
P11802STYKcsmart0022162957.9e-84
P11802S_TKcsmart00220162956.3e-100
P11802KINDsmart007501163030.00035
NP_000066PTKc_InsR_likecd0503212663.4e-07
NP_000066PTKc_EphRcd0503312658.3e-06
NP_000066PTKc_ALK_LTKcd0503612675.1e-06
NP_000066PTKc_Rorcd0504812608e-09
NP_000066PTKc_Muskcd0505012673.4e-08
NP_000066PTKc_Ablcd0505212761.6e-06
NP_000066PTKc_FGFRcd0505312323.1e-05
NP_000066PTKc_FAKcd0505612723.4e-07
NP_000066PTKc_EGFR_likecd0505712750.0001
NP_000066PTKc_InsRcd0506112786.1e-06
NP_000066PTKc_IGF-1Rcd0506212660.00018
NP_000066PTKc_EphR_Bcd0506512680.00018
NP_000066PTKc_Lck_Blkcd0506712870.00013
NP_000066PTKc_Frk_likecd0506812673e-07
NP_000066PTKc_Fyn_Yrkcd0507012670.001
NP_000066PTKc_Lyncd0507212646.5e-05
NP_000066PTKc_Hckcd0507312644.3e-05
NP_000066PTKc_Chkcd0508312670.00014
NP_000066PTKc_Ror2cd0509112672e-05
NP_000066PTKc_Ror1cd0509012671.3e-05
NP_000066PTKc_Jak1_rpt2cd0507912919.6e-06
NP_000066PTKc_HER2cd0510912910.00092
NP_000066PTKc_Itkcd0511212765.9e-07
NP_000066PTKc_Btk_Bmxcd0511312652e-05
NP_000066PTKc_Tec_Rlkcd0511412656.2e-05
NP_000066PKc_MKK4cd0661612766.8e-06
NP_000066PKc_MKK7cd0661812740.00012
NP_000066PKc_MAPKK_Byr1_likecd0662012881.8e-06
NP_000066STKc_TAO3cd0663312880.00012
NP_000066STKc_MAP4K4_6cd0663612950.00014
NP_000066STKc_PAK_IIcd0664813039.2e-09
NP_000066PKc_MEK2cd0664913032e-05
NP_000066PKc_MEK1cd0665013000.00031
NP_000066STKc_PAK2cd0665513022.3e-06
NP_000066STKc_PAK5cd0665812950.00013
NP_000066STKc_PAK6cd0665913031.2e-06
NP_000066STKc_JNKcd0785013031e-21
NP_000066STKc_ERK5cd0785513036e-22
NP_000066STKc_TEY_MAPK_plantcd0785813024.3e-42
NP_000066STKc_CDK12cd0786412956.1e-63
NP_000066STKc_CDK9cd0786512951.2e-46
NP_000066STKc_PCTAIRE2cd0787213031.4e-50
NP_000066STKc_JNK3cd0787413011.2e-12
NP_000066STKc_JNK1cd0787513031.1e-10
NP_000066STKc_JNK2cd0787613039.8e-13
NP_000066STKc_Nek7cd0822912663.3e-09
NP_000066PTK_CCK4cd0504622665e-05
NP_000066PTKc_FGFR1cd0509822920.00089
NP_000066PTKc_FGFR4cd0509922810.00042
NP_000066PTKc_TrkAcd0509222743.1e-05
NP_000066STKc_MAP4K3_likecd0661322942e-12
NP_000066STKc_myosinIII_likecd0660822301.7e-08
NP_000066STKc_ASKcd0662422771.2e-09
NP_000066STKc_TAO2cd0663422891.4e-06
NP_000066STKc_TAO1cd0663522886.3e-06
NP_000066STKc_TNIKcd0663722951.3e-05
NP_000066STKc_myosinIIIBcd0663922963.1e-06
NP_000066STKc_MST4cd0664022981.2e-05
NP_000066STKc_STK25-YSK1cd0664222988.3e-07
NP_000066STKc_SLKcd0664322933.1e-06
NP_000066STKc_STK10_LOKcd0664423002.4e-06
NP_000066STKc_MAP4K3cd0664522943.7e-07
NP_000066STKc_MAP4K5cd0664622948.6e-07
NP_000066STKc_PAK_Icd0664723027.9e-06
NP_000066STKc_PAK1cd0665423012e-06
NP_000066STKc_PAK3cd0665622952.9e-06
NP_000066STKc_MST3cd0664122982.6e-06
NP_000066STKc_myosinIIIAcd0663822951.6e-06
NP_000066STKc_PCTAIRE_likecd0784422951.1e-78
NP_000066STKc_p38cd0785123021.1e-21
NP_000066STKc_Sty1_Hog1cd0785623015.9e-36
NP_000066STKc_BUR1cd0786622959.7e-46
NP_000066STKc_PFTAIRE1cd0786922982e-51
NP_000066STKc_PFTAIRE2cd0787022951.9e-61
NP_000066STKc_PCTAIRE3cd0787122951.8e-64
NP_000066STKc_PCTAIRE1cd0787323034.3e-57
NP_000066STKc_p38alpha_MAPK14cd0787723032.3e-12
NP_000066STKc_p38beta_MAPK11cd0787823033.3e-15
NP_000066STKc_p38delta_MAPK13cd0787923033.8e-21
NP_000066STKc_p38gamma_MAPK12cd0788023031.7e-22
NP_000066STKc_GRK4_likecd0560533021.2e-06
NP_000066STKc_GRK5cd0563232980.00036
NP_000066STKc_SLK_likecd0661132939.4e-09
NP_000066STKc_PAKcd0661433031.7e-12
NP_000066STKc_MEKK2cd0665232781.6e-07
NP_000066STKc_MEKK3_like_1cd0665332739.2e-09
NP_000066STKc_ERK1_2_likecd0784933037.9e-27
NP_000066STKc_MAPK15cd0785233026.6e-27
NP_000066STKc_MAPK4_6cd0785433037.7e-25
NP_000066STKc_Nek6_Nek7cd0822432986.4e-10
NP_000066STKc_Nek6cd0822832731.6e-07
NP_000066PTKc_Jak_rpt2cd0503842961.1e-08
NP_000066PTKc_Srm_Brkcd0514842988.6e-07
NP_000066STKc_ROCK_NDR_likecd0557342971.8e-08
NP_000066STKc_phototropin_likcd0557442615e-07
NP_000066STKc_PKAcd0558042715e-07
NP_000066STKc_PDK1cd0558142957.2e-13
NP_000066STKc_Sid2p_Dbf2pcd0560042810.00019
NP_000066STKc_MASTcd0560942961.1e-07
NP_000066STKc_PRKX_likecd0561242773.2e-07
NP_000066PKc_MAPKKcd0660542831.8e-10
NP_000066STKc_TAOcd0660742895.8e-07
NP_000066STKc_MST3_likecd0660942721.5e-09
NP_000066STKc_OSR1_SPAKcd0661042957.5e-09
NP_000066PKc_MEKcd0661543022.7e-08
NP_000066PKc_MAPKK_PBS2_likecd0662242936.3e-05
NP_000066PKc_MAPKK_plant_likecd0662343002.1e-13
NP_000066STKc_NAK1_likecd0691742954.9e-09
NP_000066STKc_CdkB_plantcd0783742962.3e-95
NP_000066STKc_CDC2L1cd0784342951.5e-71
NP_000066STKc_CDK10cd0784543023.6e-77
NP_000066STKc_CDKL2_3cd0784642952.3e-34
NP_000066STKc_CDKL1_4cd0784742953e-54
NP_000066STKc_CDKL5cd0784842951e-31
NP_000066STKc_CDK6cd0786242952.8e-178
NP_000066STKc_CDKLcd0783342959.1e-42
NP_000066SPS1COG051543031.3e-29
NP_000066PTKc_Tyk2_rpt2cd0508052922e-05
NP_000066PKc_STEcd0512252949.1e-14
NP_000066STKc_Yank1cd0557852951.3e-12
NP_000066STKc_MSK_Ncd0558352890.00021
NP_000066STKc_MSK1_Ncd0561352890.0009
NP_000066STKc_MAPKKKcd0660652954.6e-30
NP_000066STKc_MEKK4cd0662652957.7e-11
NP_000066STKc_Cdc7_likecd0662752952.2e-16
NP_000066STKc_MAPKKK_Byr2_likcd0662852733.4e-18
NP_000066STKc_CCRKcd0783252962.4e-82
NP_000066STKc_MAPKcd0783453033.8e-45
NP_000066STKc_Pho85cd0783652952.7e-85
NP_000066STKc_CDK5cd0783952953.9e-92
NP_000066STKc_CDK7cd0784153023.2e-66
NP_000066STKc_CDK8_likecd0784252953.1e-54
NP_000066STKc_NLKcd0785353031.9e-17
NP_000066STKc_MPK1cd0785753032.7e-18
NP_000066STKc_TDY_MAPK_plantcd0785953027.7e-28
NP_000066STKc_CDK2_3cd0786052951e-98
NP_000066STKc_CDK1_eukcd0786152952.4e-87
NP_000066STKc_CDK4cd0786352953.1e-240
NP_000066STKc_CDC2L6cd0786752953.5e-38
NP_000066STKc_CDK8cd0786852957e-37
NP_000066STKc_Nekcd0821552956.5e-18
NP_000066STKc_Nek2cd0821752955e-12
NP_000066STKc_Nek1cd0821852955.9e-07
NP_000066STKc_Nek3cd0821952951.9e-10
NP_000066STKc_Nek8cd0822052954.2e-08
NP_000066STKc_Nek9cd0822152955.6e-08
NP_000066STKc_Nek4cd0822352956e-06
NP_000066STKc_Nek5cd0822552641.8e-06
NP_000066STKc_Nek11cd0822252956.6e-08
NP_000066STKc_FA2-likecd0852952951.6e-10
NP_000066STKc_Nek10cd0852852638.1e-09
NP_000066STKc_CNK2-likecd0853052954e-11
NP_000066PTKc_Src_likecd0503462641.2e-05
NP_000066PTKc_Tyro3cd0507462690.00023
NP_000066STKc_CMGCcd0511862952.2e-96
NP_000066STKc_PKNcd0558962930.00012
NP_000066STKc_MST1_2cd0661262959.1e-11
NP_000066STKc_CDK_likecd0782962957.3e-154
NP_000066STKc_MAK_likecd0783062955.1e-57
NP_000066STKc_MOKcd0783162957e-41
NP_000066STKc_CDK1_likecd0783562958.3e-93
NP_000066STKc_CDK4_6_likecd0783862956.3e-231
NP_000066STKc_CDK9_likecd0784062955.5e-85
NP_000066PKc_MKK3_6cd0661772957.6e-07
NP_000066PKc_MAPKK_Pek1_likecd0662172723.8e-05
NP_000066PTKc_Tie2cd0508882830.00088
NP_000066STKc_MEKK3_likecd0662582788.7e-14
NP_000066STKc_MEKK3cd0665182716.9e-10
NP_000066PTKc_Trkcd0504992668.3e-08
NP_000066PTKc_Tec_likecd0505992311.8e-06
NP_000066PTKc_Jak2_Jak3_rpt2cd0508192883.9e-07
NP_000066STKc_RSK_Ncd0558293030.00091
NP_000066STKc_p70S6Kcd0558493020.00051
NP_000066STKc_Rim15_likecd0561192980.00068
NP_000066PTKccd00192102916.6e-09
NP_000066PTKc_Csk_likecd05039102450.00016
NP_000066PTKc_Ack_likecd05040102963.9e-08
NP_000066PTKc_Fes_likecd05041102672.9e-10
NP_000066PTKc_Aatykcd05042102928.7e-05
NP_000066PTKc_Met_Roncd05058102700.00033
NP_000066PTKc_Syk_likecd05060102324.3e-07
NP_000066PTKc_Fescd05084102676.8e-08
NP_000066PTKc_Zap-70cd05115102870.00051
NP_000066PTKc_Sykcd05116102700.00047
NP_000066STKc_PKCcd05570102930.00018
NP_000066STKc_SGK2cd05603102960.00015
NP_000066STKc_nPKC_thetacd05619103026e-05
NP_000066STKc_MEKK1cd06630102793.3e-10
NP_000066PKccd00180122935.5e-68
NP_000066PTKc_Axl_likecd05035122680.0001
NP_000066PTKc_c-roscd05044122636.3e-07
NP_000066PTKc_Fercd05085122670.00011
NP_000066STKc_AGCcd05123122966.1e-13
NP_000066STKc_cGK_PKGcd05572123006.1e-09
NP_000066STKc_GRKcd05577122812e-06
NP_000066STKc_MAST_likecd05579122385.6e-11
NP_000066STKc_beta_ARKcd05606122982.4e-05
NP_000066STKc_GRK1cd05608122971.4e-05
NP_000066STKc_GRK7cd05607122670.0002
NP_000066STKc_GRK3cd05633123030.00015
NP_000066STKc_MAPKKK_Bck1_likcd06629122951e-12
NP_000066STKc_YSK4cd06631122951.4e-10
NP_000066STKc_MEKK1_plantcd06632122951.2e-15
NP_000066Pkinasepfam0006962958.4e-81
NP_000066Pkinase_Tyrpfam0771462953e-13
NP_000066TyrKcsmart0021962952.5e-11
NP_000066STYKcsmart0022162957.9e-84
NP_000066S_TKcsmart00220162956.3e-100
NP_000066KINDsmart007501163030.00035



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