Results for the gene: IGF1R

Results for Proteins associated with the Gene: IGF1R

IGF1R

3480

P08069 NP_000866

NCBI

Known Diseases associated with this Protein:

INSULIN-LIKE GROWTH FACTOR 1 RESISTANCE (IGF1RES)

INSULIN-LIKE GROWTH FACTOR I, RESISTANCE TO

			8 11 5 0 14

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Default View: FU - smart00261 FN3 - smart00060 STYKc - smart00221 Pkinase_Tyr - pfam07714 TyrKc - smart00219 S_TKc - smart00220	Swiss-Prot Protein: P08069 Identical to: NP_000866 Default View:

RefSeq Protein: NP_000866

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000866	FN3	cd00063	489	606	5.2e-10
NP_000866	FN3	cd00063	832	924	1.1e-06
NP_000866	PTKc_Kit	cd05104	956	1270	6.8e-28
NP_000866	PTKc_PDGFR_beta	cd05107	956	1271	1.2e-16
NP_000866	PTKc_PDGFR_alpha	cd05105	956	1273	5.4e-18
NP_000866	PTKc_CSF-1R	cd05106	960	1271	1.8e-36
NP_000866	STKc_myosinIIIB	cd06639	972	1267	0.00066
NP_000866	STKc_PAK_I	cd06647	974	1289	0.00017
NP_000866	PTKc_PDGFR	cd05055	975	1270	1.2e-20
NP_000866	STKc_PAK5	cd06658	975	1278	0.0005
NP_000866	STKc_PAK6	cd06659	976	1284	6.1e-06
NP_000866	STKc_TAO2	cd06634	977	1291	0.00021
NP_000866	STKc_PAK2	cd06655	977	1275	5.5e-05
NP_000866	STKc_PAK3	cd06656	977	1275	4.1e-05
NP_000866	STKc_PAK4	cd06657	977	1286	0.00092
NP_000866	STKc_PAK_II	cd06648	978	1270	4.5e-06
NP_000866	STKc_myosinIIIA	cd06638	980	1268	4.4e-05
NP_000866	STKc_STK10_LOK	cd06644	981	1285	2.6e-06
NP_000866	STKc_p38	cd07851	981	1307	0.00078
NP_000866	STKc_ERK5	cd07855	981	1300	0.00078
NP_000866	PTKc_FGFR1	cd05098	982	1284	2.3e-69
NP_000866	STKc_PAK1	cd06654	982	1273	0.0001
NP_000866	PTKc_FGFR2	cd05101	985	1277	1.3e-65
NP_000866	PTKc_FGFR	cd05053	986	1271	8.1e-79
NP_000866	PTKc_EGFR_like	cd05057	986	1280	1.7e-48
NP_000866	PTKc_FGFR4	cd05099	986	1280	2.1e-67
NP_000866	PTKc_EGFR	cd05108	986	1317	2.9e-36
NP_000866	PTKc_HER2	cd05109	986	1280	3.9e-40
NP_000866	PTKc_HER4	cd05110	986	1299	1.1e-30
NP_000866	PTK_HER3	cd05111	986	1280	5.6e-24
NP_000866	PTKc_Tie2	cd05088	987	1286	3.4e-40
NP_000866	PTKc_FGFR3	cd05100	988	1324	2.7e-58
NP_000866	STKc_PAK	cd06614	989	1278	8.1e-11
NP_000866	STKc_MEKK3_like	cd06625	989	1268	6.3e-09
NP_000866	STKc_CDK10	cd07845	989	1304	3.4e-05
NP_000866	STKc_PDK1	cd05581	990	1268	1.8e-09
NP_000866	PKc_MKK7	cd06618	990	1280	3.8e-08
NP_000866	STKc_ASK	cd06624	990	1268	3e-08
NP_000866	PTKc_VEGFR	cd05054	991	1273	5.7e-34
NP_000866	PTKc_VEGFR2	cd05103	991	1273	5.4e-33
NP_000866	PTKc_VEGFR3	cd05102	991	1270	7.4e-40
NP_000866	PTKc_Src_like	cd05034	992	1270	8.5e-68
NP_000866	PTKc_ALK_LTK	cd05036	992	1268	1.8e-106
NP_000866	PTKc_Csk_like	cd05039	992	1269	9.1e-41
NP_000866	PTKc_Abl	cd05052	992	1270	1.1e-74
NP_000866	PTKc_FAK	cd05056	992	1272	4.4e-82
NP_000866	PTKc_InsR	cd05061	992	1279	1.6e-220
NP_000866	PTKc_IGF-1R	cd05062	992	1268	1.1e-254
NP_000866	PTKc_Lck_Blk	cd05067	992	1270	1.1e-58
NP_000866	PTKc_Frk_like	cd05068	992	1270	5.2e-73
NP_000866	PTKc_Yes	cd05069	992	1270	4.8e-56
NP_000866	PTKc_Fyn_Yrk	cd05070	992	1270	6.6e-52
NP_000866	PTKc_Src	cd05071	992	1272	1.1e-51
NP_000866	PTKc_Lyn	cd05072	992	1270	1e-58
NP_000866	PTKc_Csk	cd05082	992	1269	2.6e-56
NP_000866	PTKc_Chk	cd05083	992	1269	5.5e-57
NP_000866	PTKc_InsR_like	cd05032	992	1268	6.1e-227
NP_000866	PTKc_Hck	cd05073	992	1270	9.4e-57
NP_000866	PTKc_Srm_Brk	cd05148	992	1266	4.4e-59
NP_000866	STKc_TEY_MAPK_plant	cd07858	992	1318	0.00022
NP_000866	STKc_CDK12	cd07864	992	1275	2.6e-06
NP_000866	PTK_CCK4	cd05046	993	1268	8.6e-60
NP_000866	PTKc_Ror	cd05048	993	1269	5.4e-78
NP_000866	PTKc_DDR	cd05051	993	1268	2e-69
NP_000866	PTKc_Trk	cd05049	993	1268	5.6e-95
NP_000866	PTKc_EphR_A2	cd05063	993	1270	4.8e-63
NP_000866	PTKc_EphR_A10	cd05064	993	1270	6.1e-55
NP_000866	PTKc_Musk	cd05050	993	1268	1.5e-101
NP_000866	PTKc_Ror1	cd05090	993	1269	1.1e-63
NP_000866	PTKc_Ror2	cd05091	993	1269	1.1e-56
NP_000866	PTKc_TrkA	cd05092	993	1276	1.3e-84
NP_000866	PTKc_TrkB	cd05093	993	1276	2e-78
NP_000866	PTKc_TrkC	cd05094	993	1276	9.3e-54
NP_000866	PTKc_DDR2	cd05095	993	1268	1.9e-70
NP_000866	PTKc_DDR1	cd05096	993	1268	1.6e-55
NP_000866	PTKc_DDR_like	cd05097	993	1268	1.3e-65
NP_000866	PKc_MAPKK_Byr1_like	cd06620	993	1268	4.1e-06
NP_000866	STKc_SLK	cd06643	993	1278	6.7e-06
NP_000866	STKc_MAP4K3	cd06645	993	1267	5.7e-05
NP_000866	STKc_MAP4K5	cd06646	993	1267	5.1e-05
NP_000866	STKc_MAPK15	cd07852	993	1294	0.0005
NP_000866	PTK_Ryk	cd05043	994	1270	7.4e-30
NP_000866	PTKc_EphR	cd05033	994	1270	2.5e-73
NP_000866	PTKc_Tec_like	cd05059	994	1267	6.1e-53
NP_000866	PTKc_EphR_B	cd05065	994	1270	4.8e-55
NP_000866	PTKc_Jak1_rpt2	cd05079	994	1270	1.9e-31
NP_000866	PTKc_Jak_rpt2	cd05038	994	1270	3e-61
NP_000866	PTKc_Itk	cd05112	994	1267	3.6e-63
NP_000866	PTKc_Tec_Rlk	cd05114	994	1267	2.8e-61
NP_000866	PTKc_Btk_Bmx	cd05113	994	1267	2.2e-63
NP_000866	PTKc_EphR_A	cd05066	994	1270	1.7e-60
NP_000866	PTKc_Jak2_Jak3_rpt2	cd05081	995	1270	1.2e-33
NP_000866	STKc_myosinIII_like	cd06608	995	1260	8.1e-06
NP_000866	STKc_MAP4K3_like	cd06613	995	1267	7.4e-09
NP_000866	PKc_MKK4	cd06616	995	1281	1.1e-05
NP_000866	STKc_MST4	cd06640	995	1278	7.4e-07
NP_000866	STKc_STK25-YSK1	cd06642	995	1278	7e-08
NP_000866	STKc_MST3	cd06641	995	1289	4.8e-07
NP_000866	STKc_CDK5	cd07839	995	1279	4.8e-05
NP_000866	STKc_PCTAIRE_like	cd07844	995	1298	0.00011
NP_000866	STKc_SLK_like	cd06611	996	1276	3e-06
NP_000866	STKc_MEKK2	cd06652	996	1269	0.00056
NP_000866	STKc_MEKK3_like_1	cd06653	996	1268	0.00012
NP_000866	STKc_Nek6_Nek7	cd08224	996	1272	1.2e-07
NP_000866	PTKc_Tie1	cd05089	997	1291	4.4e-41
NP_000866	STKc_PRKX_like	cd05612	997	1304	0.00015
NP_000866	PKc_MAPKK	cd06605	997	1265	9.6e-06
NP_000866	STKc_OSR1_SPAK	cd06610	997	1260	8.7e-09
NP_000866	PKc_MEK	cd06615	997	1287	3.9e-05
NP_000866	STKc_MST3_like	cd06609	997	1277	1.5e-10
NP_000866	PKc_MKK3_6	cd06617	997	1285	1.8e-07
NP_000866	PKc_MAPKK_PBS2_like	cd06622	997	1286	3.2e-05
NP_000866	PKc_MAPKK_plant_like	cd06623	997	1271	1.1e-11
NP_000866	PKc_MAPKK_Pek1_like	cd06621	997	1278	1.9e-05
NP_000866	STKc_CDKL	cd07833	997	1259	0.00076
NP_000866	STKc_CdkB_plant	cd07837	997	1269	3.2e-06
NP_000866	STKc_CDKL2_3	cd07846	997	1265	0.00083
NP_000866	STKc_CDKL1_4	cd07847	997	1319	0.00024
NP_000866	STKc_PCTAIRE2	cd07872	997	1315	0.0004
NP_000866	STKc_Nek6	cd08228	997	1272	1.8e-05
NP_000866	STKc_Nek7	cd08229	997	1271	1.3e-06
NP_000866	SPS1	COG0515	997	1367	1.3e-18
NP_000866	PTKc_RET	cd05045	998	1273	7.9e-67
NP_000866	PKc_STE	cd05122	998	1259	4.3e-12
NP_000866	STKc_cPKC	cd05587	998	1350	0.00012
NP_000866	STKc_GRK4_like	cd05605	998	1295	1.1e-06
NP_000866	STKc_GRK6	cd05630	998	1295	0.00013
NP_000866	STKc_GRK4	cd05631	998	1295	2.7e-05
NP_000866	STKc_GRK5	cd05632	998	1295	3.1e-05
NP_000866	STKc_MAPKKK	cd06606	998	1260	1.6e-19
NP_000866	STKc_YSK4	cd06631	998	1266	3.1e-09
NP_000866	STKc_Cdc7_like	cd06627	998	1260	1e-09
NP_000866	STKc_MAPKKK_Byr2_lik	cd06628	998	1268	7.2e-08
NP_000866	STKc_MEKK3	cd06651	998	1270	2.5e-06
NP_000866	STKc_CCRK	cd07832	998	1260	1.8e-07
NP_000866	STKc_Pho85	cd07836	998	1298	2.6e-05
NP_000866	STKc_MAPK	cd07834	998	1297	4.6e-06
NP_000866	STKc_CDK7	cd07841	998	1272	4e-09
NP_000866	STKc_MPK1	cd07857	998	1303	0.00049
NP_000866	STKc_NLK	cd07853	998	1317	0.00069
NP_000866	STKc_CDK2_3	cd07860	998	1298	0.00073
NP_000866	STKc_CDK1_euk	cd07861	998	1305	0.00035
NP_000866	STKc_CDK4	cd07863	998	1298	0.00064
NP_000866	STKc_Nek1	cd08218	998	1270	1e-05
NP_000866	STKc_Nek3	cd08219	998	1268	7.5e-09
NP_000866	STKc_Nek8	cd08220	998	1267	0.00011
NP_000866	STKc_Nek9	cd08221	998	1268	1.1e-06
NP_000866	STKc_Nek11	cd08222	998	1268	2.4e-07
NP_000866	STKc_Nek4	cd08223	998	1266	1.2e-06
NP_000866	STKc_Nek5	cd08225	998	1268	8.2e-06
NP_000866	STKc_Nek	cd08215	998	1268	4.3e-13
NP_000866	STKc_Nek10	cd08528	998	1268	1.7e-06
NP_000866	STKc_CNK2-like	cd08530	998	1266	6.4e-08
NP_000866	PTKc_Axl_like	cd05035	999	1270	1.9e-81
NP_000866	PTKc_Tyro3	cd05074	999	1270	2.2e-76
NP_000866	PTKc_Axl	cd05075	999	1270	6.5e-72
NP_000866	PTKc_Tyk2_rpt2	cd05080	999	1271	9e-28
NP_000866	STKc_PKN	cd05589	999	1328	0.00068
NP_000866	STKc_CDK1_like	cd07835	999	1298	9.4e-06
NP_000866	STKc_Yank1	cd05578	1000	1266	4.3e-05
NP_000866	STKc_NAK1_like	cd06917	1000	1282	3.1e-06
NP_000866	STKc_CDK_like	cd07829	1000	1260	8.4e-11
NP_000866	STKc_MAK_like	cd07830	1000	1260	2.1e-09
NP_000866	STKc_MEKK1_plant	cd06632	1001	1260	3.7e-09
NP_000866	STKc_MAPKKK_Bck1_lik	cd06629	1001	1260	6.9e-06
NP_000866	STKc_BUR1	cd07866	1001	1259	0.00026
NP_000866	STKc_RSK_N	cd05582	1002	1332	2.9e-05
NP_000866	STKc_MEKK4	cd06626	1002	1260	8.4e-05
NP_000866	STKc_CDK4_6_like	cd07838	1002	1260	6.1e-07
NP_000866	PTKc	cd00192	1003	1267	8.8e-146
NP_000866	PTK_Jak_rpt1	cd05037	1003	1267	7.5e-12
NP_000866	PTKc_Ack_like	cd05040	1003	1268	1.7e-54
NP_000866	PTKc_Aatyk	cd05042	1003	1265	3.9e-38
NP_000866	PTKc_c-ros	cd05044	1003	1268	1.2e-110
NP_000866	PTKc_Met_Ron	cd05058	1003	1272	1.1e-75
NP_000866	PTKc_Syk_like	cd05060	1003	1271	3e-62
NP_000866	PTK_Tyk2_rpt1	cd05076	1003	1267	9.5e-07
NP_000866	PTK_Jak1_rpt1	cd05077	1003	1267	2.1e-10
NP_000866	PTK_Jak2_Jak3_rpt1	cd05078	1003	1267	1.7e-12
NP_000866	PTKc_Fes	cd05084	1003	1268	2.6e-69
NP_000866	PTKc_Aatyk2	cd05086	1003	1268	1.5e-35
NP_000866	PTKc_Aatyk1_Aatyk3	cd05087	1003	1268	1.3e-48
NP_000866	PTKc_Fes_like	cd05041	1003	1268	4e-67
NP_000866	PTKc_Syk	cd05116	1003	1271	3.1e-48
NP_000866	STKc_CMGC	cd05118	1003	1260	1.5e-09
NP_000866	STKc_PKC	cd05570	1003	1303	0.00022
NP_000866	STKc_PKB	cd05571	1003	1345	0.00013
NP_000866	STKc_nPKC_epsilon	cd05591	1003	1337	0.001
NP_000866	STKc_nPKC_theta_delt	cd05592	1003	1328	0.00023
NP_000866	STKc_PKB_gamma	cd05593	1003	1317	0.00049
NP_000866	STKc_nPKC_theta	cd05619	1003	1317	7.1e-05
NP_000866	STKc_MEKK1	cd06630	1003	1275	2.6e-06
NP_000866	STKc_CDK9_like	cd07840	1003	1259	2.6e-05
NP_000866	STKc_MAPK4_6	cd07854	1003	1308	0.00065
NP_000866	STKc_Nek2	cd08217	1003	1266	3.4e-10
NP_000866	STKc_FA2-like	cd08529	1003	1266	6.4e-12
NP_000866	PTKc_Zap-70	cd05115	1004	1271	2.1e-45
NP_000866	PKc	cd00180	1005	1266	2.2e-64
NP_000866	PTKc_Tie	cd05047	1005	1271	1.2e-49
NP_000866	PTKc_Fer	cd05085	1005	1268	4e-64
NP_000866	STKc_AGC	cd05123	1005	1265	6e-06
NP_000866	STKc_cGK_PKG	cd05572	1005	1281	2.9e-06
NP_000866	STKc_GRK	cd05577	1005	1294	3.7e-06
NP_000866	STKc_MAST_like	cd05579	1005	1268	0.00011
NP_000866	STKc_beta_ARK	cd05606	1005	1298	0.00043
NP_000866	STKc_GRK7	cd05607	1005	1294	0.00027
NP_000866	STKc_GRK1	cd05608	1005	1294	1.3e-06
NP_000866	STKc_MST1_2	cd06612	1005	1260	1e-08
NP_000866	STKc_MOK	cd07831	1005	1259	2.3e-06
NP_000866	Recep_L_domain	pfam01030	51	161	1.1e-44
NP_000866	Furin-like	pfam00757	175	333	3.2e-79
NP_000866	Recep_L_domain	pfam01030	352	467	6.6e-45
NP_000866	Pkinase	pfam00069	999	1266	1.4e-36
NP_000866	FU	smart00261	227	270	4.8e-14
NP_000866	FN3	smart00060	489	591	5.5e-06
NP_000866	FN3	smart00060	832	914	9.9e-07
NP_000866	Pkinase_Tyr	pfam07714	999	1266	2.4e-154
NP_000866	TyrKc	smart00219	999	1266	9.1e-144
NP_000866	STYKc	smart00221	999	1268	1.2e-52
NP_000866	S_TKc	smart00220	1009	1270	1.6e-40

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258