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Known Diseases associated with this Protein:
  ALZHEIMER DISEASE 1 (AD1)
  ALZHEIMER DISEASE, FAMILIAL, 1
  ALZHEIMER DISEASE, FAMILIAL, 1, AUTOSOMAL RECESSIVE
  ALZHEIMER DISEASE, FAMILIAL, 1, INCLUDED
  ALZHEIMER DISEASE, PROTECTION AGAINST
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED (CAA-APP)
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ARCTIC VARIANT, INCLUDED
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, DUTCH VARIANT
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, FLEMISH VARIANT
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, IOWA VARIANT
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ITALIAN VARIANT
  CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, PIEDMONT VARIANT
197
3
180
0
20
Tips:
 The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.
 Clicking a check box on the left will display or hide the corresponding domain(s).
 To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.


Default View:

A4_EXTRA - smart00006
KU - smart00131
APP_amyloid - pfam10515


Swiss-Prot Protein: P05067
Identical to: NP_000475
   Default View:


Default View:

A4_EXTRA - smart00006
APP_N - pfam02177
KU - cd00109
KU - smart00131
Kunitz_BPTI - pfam00014
Beta-APP - pfam03494
APP_amyloid - pfam10515



Default View:

APP_N - pfam02177
A4_EXTRA - smart00006
Beta-APP - pfam03494
APP_amyloid - pfam10515


RefSeq Protein: NP_958817
   Default View:



Default View:

A4_EXTRA - smart00006
APP_N - pfam02177
KU - cd00109
KU - smart00131
Kunitz_BPTI - pfam00014
Beta-APP - pfam03494
APP_amyloid - pfam10515


RefSeq Protein: NP_958816
   Default View:




Default View:

APP_N - pfam02177
A4_EXTRA - smart00006
Beta-APP - pfam03494
APP_amyloid - pfam10515



Default View:

A4_EXTRA - smart00006
APP_N - pfam02177
KU - cd00109
KU - smart00131
Kunitz_BPTI - pfam00014
Beta-APP - pfam03494
APP_amyloid - pfam10515



Default View:

APP_N - pfam02177
A4_EXTRA - smart00006
Beta-APP - pfam03494
APP_amyloid - pfam10515



Default View:

A4_EXTRA - smart00006
APP_N - pfam02177
KU - cd00109
KU - smart00131
Kunitz_BPTI - pfam00014
Beta-APP - pfam03494
APP_amyloid - pfam10515



Default View:

A4_EXTRA - smart00006
APP_N - pfam02177
KU - cd00109
KU - smart00131
Kunitz_BPTI - pfam00014
Beta-APP - pfam03494
APP_amyloid - pfam10515



Default View:

A4_EXTRA - smart00006
APP_N - pfam02177
KU - cd00109
KU - smart00131
Kunitz_BPTI - pfam00014
Beta-APP - pfam03494
APP_amyloid - pfam10515


RefSeq Protein: NP_000475
   Default View:




Default View:

APP_N - pfam02177
A4_EXTRA - smart00006
Beta-APP - pfam03494
APP_amyloid - pfam10515




Domains found on the Proteins

Protein ↕Domain ↕Domain Accession ↕Start ↕End ↕E-Value ↕
P05067A4_EXTRAsmart00006241884.4e-131
P05067KUsmart001312893411.1e-26
P05067APP_amyloidpfam105157147661.3e-36
NP_001191231KUcd001092893421.8e-28
NP_001191231APP_Npfam02177241882.9e-132
NP_001191231Kunitz_BPTIpfam000142903424.6e-27
NP_001191231Beta-APPpfam034946386766.9e-27
NP_001191231A4_EXTRAsmart00006241884.4e-131
NP_001191231KUsmart001312893411.1e-26
NP_001191231APP_amyloidpfam105156777291.3e-36
NP_958817APP_Npfam02177241882.9e-132
NP_958817Beta-APPpfam034946006386.9e-27
NP_958817A4_EXTRAsmart00006241884.4e-131
NP_958817APP_amyloidpfam105156396911.3e-36
NP_958816KUcd001092893421.8e-28
NP_958816APP_Npfam02177241882.9e-132
NP_958816Kunitz_BPTIpfam000142903424.6e-27
NP_958816Beta-APPpfam034946566946.9e-27
NP_958816A4_EXTRAsmart00006241884.4e-131
NP_958816KUsmart001312893411.1e-26
NP_958816APP_amyloidpfam105156957471.3e-36
NP_001191232APP_Npfam02177241882.9e-132
NP_001191232Beta-APPpfam034945826206.9e-27
NP_001191232A4_EXTRAsmart00006241884.4e-131
NP_001191232APP_amyloidpfam105156216731.3e-36
NP_001191230KUcd001092893421.8e-28
NP_001191230APP_Npfam02177241882.9e-132
NP_001191230Kunitz_BPTIpfam000142903424.6e-27
NP_001191230Beta-APPpfam034946576956.9e-27
NP_001191230A4_EXTRAsmart00006241884.4e-131
NP_001191230KUsmart001312893411.1e-26
NP_001191230APP_amyloidpfam105156967481.3e-36
NP_001129603APP_Npfam0217711534.9e-118
NP_001129603Beta-APPpfam034945656036.9e-27
NP_001129603A4_EXTRAsmart0000611534.1e-117
NP_001129603APP_amyloidpfam105156046561.3e-36
NP_001129602KUcd001092332861.8e-28
NP_001129602APP_Npfam0217711322.3e-76
NP_001129602Kunitz_BPTIpfam000142342864.6e-27
NP_001129602Beta-APPpfam034946196576.9e-27
NP_001129602A4_EXTRAsmart0000611328.2e-75
NP_001129602KUsmart001312332851.1e-26
NP_001129602APP_amyloidpfam105156587101.3e-36
NP_001129488KUcd001092843371.8e-28
NP_001129488APP_Npfam02177191832.9e-132
NP_001129488Kunitz_BPTIpfam000142853374.6e-27
NP_001129488Beta-APPpfam034946516896.9e-27
NP_001129488A4_EXTRAsmart00006191834.4e-131
NP_001129488KUsmart001312843361.1e-26
NP_001129488APP_amyloidpfam105156907421.3e-36
NP_000475KUcd001092893421.8e-28
NP_000475APP_Npfam02177241882.9e-132
NP_000475Kunitz_BPTIpfam000142903424.6e-27
NP_000475Beta-APPpfam034946757136.9e-27
NP_000475A4_EXTRAsmart00006241884.4e-131
NP_000475KUsmart001312893411.1e-26
NP_000475APP_amyloidpfam105157147661.3e-36
NP_001129601APP_Npfam0217711322.3e-76
NP_001129601Beta-APPpfam034945445826.9e-27
NP_001129601A4_EXTRAsmart0000611328.2e-75
NP_001129601APP_amyloidpfam105155836351.3e-36



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