Results for the gene: INSR

Results for Proteins associated with the Gene: INSR

INSR

3643

P06213 NP_001073285 NP_000199

NCBI

Known Diseases associated with this Protein:

DIABETES MELLITUS, INSULIN-RESISTANT

DIABETES MELLITUS, INSULIN-RESISTANT, WITH ACANTHOSIS NIGRICANS

DIABETES MELLITUS, NON-INSULIN-DEPENDENT (NIDDM)

DIABETES MELLITUS, NONINSULIN-DEPENDENT

DONOHUE SYNDROME

HYPERINSULINEMIC HYPOGLYCEMIA, FAMILIAL, 5

INSULIN RESISTANCE

INSULIN RESISTANCE, INCLUDED

INSULIN-RESISTANT DIABETES MELLITUS WITH ACANTHOSIS NIGRICANS TYPE A (IRAN TYPE A)

LEPRECHAUNISM (LEPRCH)

RABSON-MENDENHALL SYNDROME

RABSON-MENDENHALL SYNDROME (RMS)

			107 16 58 0 65

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P06213

Identical to: NP_000199

Default View:

RefSeq Protein: NP_001073285

Default View:

RefSeq Protein: NP_000199

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000199	FN3	cd00063	850	944	7.5e-09
NP_000199	PTKc_CSF-1R	cd05106	989	1295	1e-38
NP_000199	PTKc_Kit	cd05104	990	1294	1.2e-29
NP_000199	PTKc_PDGFR_alpha	cd05105	991	1297	1.6e-18
NP_000199	PTKc_PDGFR	cd05055	992	1294	7.5e-25
NP_000199	PTKc_PDGFR_beta	cd05107	992	1295	7.4e-14
NP_000199	STKc_PAK1	cd06654	995	1312	1.3e-05
NP_000199	STKc_PAK_I	cd06647	996	1313	0.00017
NP_000199	STKc_PAK3	cd06656	996	1315	1.4e-05
NP_000199	STKc_PAK6	cd06659	1001	1311	2e-06
NP_000199	STKc_TAO1	cd06635	1002	1330	0.00044
NP_000199	STKc_PAK4	cd06657	1002	1325	0.0004
NP_000199	STKc_PAK5	cd06658	1002	1305	0.00047
NP_000199	STKc_PAK_II	cd06648	1003	1302	1.1e-06
NP_000199	STKc_TAO2	cd06634	1004	1331	2.1e-05
NP_000199	STKc_myosinIIIA	cd06638	1006	1295	1e-05
NP_000199	STKc_p38	cd07851	1006	1353	2.7e-05
NP_000199	PTKc_FGFR1	cd05098	1008	1300	1.9e-63
NP_000199	PTKc_FGFR2	cd05101	1009	1301	1.6e-61
NP_000199	PTKc_FGFR	cd05053	1010	1295	8e-83
NP_000199	PTKc_FGFR4	cd05099	1010	1313	4.2e-65
NP_000199	PTKc_EGFR	cd05108	1010	1337	9e-33
NP_000199	PTKc_HER4	cd05110	1010	1323	2.3e-31
NP_000199	PTKc_Tie2	cd05088	1011	1316	7.6e-40
NP_000199	STKc_STK10_LOK	cd06644	1011	1317	9.9e-07
NP_000199	PTKc_FGFR3	cd05100	1012	1323	6.3e-56
NP_000199	STKc_ASK	cd06624	1012	1295	2.9e-09
NP_000199	STKc_PAK	cd06614	1013	1302	2.6e-11
NP_000199	STKc_MEKK3_like	cd06625	1013	1292	4.7e-09
NP_000199	PKc_MKK7	cd06618	1014	1309	7.1e-07
NP_000199	STKc_PAK2	cd06655	1014	1316	3.5e-05
NP_000199	PTKc_VEGFR	cd05054	1015	1297	3.4e-39
NP_000199	PTKc_VEGFR3	cd05102	1015	1297	2.6e-48
NP_000199	PTKc_VEGFR2	cd05103	1015	1297	2.6e-38
NP_000199	STKc_TAO	cd06607	1015	1330	0.00039
NP_000199	STKc_MAPK15	cd07852	1015	1340	3.8e-05
NP_000199	PTKc_InsR_like	cd05032	1016	1292	4.3e-226
NP_000199	PTKc_Src_like	cd05034	1016	1293	1.5e-67
NP_000199	PTKc_ALK_LTK	cd05036	1016	1292	5e-109
NP_000199	PTKc_Csk_like	cd05039	1016	1290	9.5e-46
NP_000199	PTKc_Abl	cd05052	1016	1294	2.8e-69
NP_000199	PTKc_FAK	cd05056	1016	1298	1.2e-78
NP_000199	PTKc_InsR	cd05061	1016	1303	1.9e-251
NP_000199	PTKc_IGF-1R	cd05062	1016	1292	8.8e-216
NP_000199	PTKc_Lck_Blk	cd05067	1016	1293	3.1e-57
NP_000199	PTKc_Frk_like	cd05068	1016	1293	1.9e-74
NP_000199	PTKc_Yes	cd05069	1016	1293	1.4e-52
NP_000199	PTKc_Src	cd05071	1016	1295	3.4e-50
NP_000199	PTKc_Lyn	cd05072	1016	1293	1.2e-59
NP_000199	PTKc_Hck	cd05073	1016	1293	8.6e-57
NP_000199	PTKc_Fyn_Yrk	cd05070	1016	1293	9.2e-52
NP_000199	PTKc_Csk	cd05082	1016	1293	7.7e-59
NP_000199	PTKc_Chk	cd05083	1016	1293	1.1e-58
NP_000199	PTKc_HER2	cd05109	1016	1303	1.3e-42
NP_000199	PTKc_Srm_Brk	cd05148	1016	1297	1.5e-59
NP_000199	STKc_ERK1_2_like	cd07849	1016	1326	0.0003
NP_000199	STKc_ERK5	cd07855	1016	1324	0.00027
NP_000199	STKc_TEY_MAPK_plant	cd07858	1016	1363	0.0002
NP_000199	STKc_CDK12	cd07864	1016	1317	1.9e-07
NP_000199	PTK_CCK4	cd05046	1017	1292	5.5e-61
NP_000199	PTKc_Ror	cd05048	1017	1293	1e-79
NP_000199	PTKc_Musk	cd05050	1017	1292	4.6e-100
NP_000199	PTKc_Trk	cd05049	1017	1292	1.3e-101
NP_000199	PTKc_EphR_A10	cd05064	1017	1294	1.4e-57
NP_000199	PTKc_EphR_A2	cd05063	1017	1294	4.5e-67
NP_000199	PTKc_DDR	cd05051	1017	1292	1.3e-69
NP_000199	PTKc_EphR_B	cd05065	1017	1294	7.4e-57
NP_000199	PTKc_Ror1	cd05090	1017	1293	1.6e-61
NP_000199	PTKc_Ror2	cd05091	1017	1293	1.5e-58
NP_000199	PTKc_TrkA	cd05092	1017	1300	3.5e-88
NP_000199	PTKc_TrkB	cd05093	1017	1302	5.1e-81
NP_000199	PTKc_TrkC	cd05094	1017	1300	2.3e-57
NP_000199	PTKc_DDR2	cd05095	1017	1292	1.4e-68
NP_000199	PTKc_DDR_like	cd05097	1017	1292	1.8e-66
NP_000199	PTKc_DDR1	cd05096	1017	1292	3.7e-56
NP_000199	PKc_MAPKK_Byr1_like	cd06620	1017	1299	5e-05
NP_000199	STKc_SLK	cd06643	1017	1311	1.9e-06
NP_000199	STKc_MAP4K3	cd06645	1017	1294	6.2e-06
NP_000199	STKc_MAP4K5	cd06646	1017	1291	5.8e-06
NP_000199	PTKc_EphR	cd05033	1018	1294	1.2e-76
NP_000199	PTKc_Jak_rpt2	cd05038	1018	1295	1.6e-53
NP_000199	PTK_Ryk	cd05043	1018	1294	5.3e-36
NP_000199	PTKc_EphR_A	cd05066	1018	1295	2e-62
NP_000199	PTKc_Jak2_Jak3_rpt2	cd05081	1018	1295	7.5e-35
NP_000199	PTKc_Tec_like	cd05059	1018	1291	4.8e-53
NP_000199	PTK_HER3	cd05111	1018	1302	5.8e-27
NP_000199	PTKc_Itk	cd05112	1018	1291	4.6e-60
NP_000199	PTKc_Btk_Bmx	cd05113	1018	1291	4.3e-65
NP_000199	PTKc_Tec_Rlk	cd05114	1018	1291	7.5e-60
NP_000199	STKc_CDK10	cd07845	1018	1299	4e-08
NP_000199	STKc_BUR1	cd07866	1018	1298	5.7e-06
NP_000199	PTKc_EGFR_like	cd05057	1019	1302	9.9e-49
NP_000199	STKc_MAP4K3_like	cd06613	1019	1294	2.3e-10
NP_000199	PKc_MKK4	cd06616	1019	1308	9.4e-06
NP_000199	STKc_TNIK	cd06637	1019	1298	0.00081
NP_000199	STKc_MST4	cd06640	1019	1310	5.4e-07
NP_000199	STKc_MST3	cd06641	1019	1310	9.8e-07
NP_000199	STKc_STK25-YSK1	cd06642	1019	1313	3.6e-08
NP_000199	STKc_PCTAIRE_like	cd07844	1019	1322	0.00013
NP_000199	STKc_PFTAIRE2	cd07870	1019	1328	0.00055
NP_000199	STKc_SLK_like	cd06611	1020	1320	1.5e-06
NP_000199	STKc_MST1_2	cd06612	1020	1284	1.5e-08
NP_000199	STKc_MEKK2	cd06652	1020	1295	0.00048
NP_000199	STKc_MEKK3_like_1	cd06653	1020	1292	8.4e-05
NP_000199	STKc_Nek6_Nek7	cd08224	1020	1295	6.5e-07
NP_000199	PTKc_Jak1_rpt2	cd05079	1021	1294	2.3e-31
NP_000199	PTKc_Tie1	cd05089	1021	1313	2.3e-37
NP_000199	STKc_ROCK_NDR_like	cd05573	1021	1364	3.8e-05
NP_000199	STKc_PKA	cd05580	1021	1324	0.00027
NP_000199	STKc_MAST	cd05609	1021	1350	4.1e-05
NP_000199	STKc_PRKX_like	cd05612	1021	1325	3.3e-05
NP_000199	PKc_MAPKK	cd06605	1021	1288	4.1e-05
NP_000199	STKc_myosinIII_like	cd06608	1021	1290	1e-06
NP_000199	STKc_MST3_like	cd06609	1021	1302	4.8e-10
NP_000199	STKc_OSR1_SPAK	cd06610	1021	1298	4.1e-09
NP_000199	PKc_MKK3_6	cd06617	1021	1310	7.3e-08
NP_000199	PKc_MEK	cd06615	1021	1311	0.00024
NP_000199	PKc_MAPKK_Pek1_like	cd06621	1021	1294	1.8e-05
NP_000199	PKc_MAPKK_PBS2_like	cd06622	1021	1332	5.3e-06
NP_000199	PKc_MAPKK_plant_like	cd06623	1021	1288	4.6e-11
NP_000199	STKc_CDKL	cd07833	1021	1298	0.00052
NP_000199	STKc_CdkB_plant	cd07837	1021	1299	7.3e-08
NP_000199	STKc_CDKL2_3	cd07846	1021	1295	0.0001
NP_000199	STKc_CDK6	cd07862	1021	1322	1.4e-05
NP_000199	STKc_CDKL1_4	cd07847	1021	1327	2e-05
NP_000199	STKc_Nek6	cd08228	1021	1296	3.6e-05
NP_000199	STKc_Nek7	cd08229	1021	1296	2.1e-06
NP_000199	SPS1	COG0515	1021	1382	3.7e-18
NP_000199	PTKc_RET	cd05045	1022	1297	1.7e-64
NP_000199	PKc_STE	cd05122	1022	1294	7.4e-13
NP_000199	STKc_cPKC	cd05587	1022	1365	1.6e-05
NP_000199	STKc_GRK4_like	cd05605	1022	1325	1.4e-07
NP_000199	STKc_GRK6	cd05630	1022	1325	3.2e-05
NP_000199	STKc_GRK4	cd05631	1022	1314	3.9e-06
NP_000199	STKc_GRK5	cd05632	1022	1317	1e-05
NP_000199	STKc_Cdc7_like	cd06627	1022	1284	4.3e-11
NP_000199	STKc_MAPKKK_Byr2_lik	cd06628	1022	1295	6.6e-08
NP_000199	STKc_MAPKKK	cd06606	1022	1284	4.5e-19
NP_000199	STKc_MEKK3	cd06651	1022	1294	6.6e-07
NP_000199	STKc_CCRK	cd07832	1022	1299	1.1e-08
NP_000199	STKc_Pho85	cd07836	1022	1322	1.2e-05
NP_000199	STKc_CDK5	cd07839	1022	1322	1.7e-05
NP_000199	STKc_CDK7	cd07841	1022	1296	1.4e-07
NP_000199	STKc_MAPK	cd07834	1022	1324	6.8e-08
NP_000199	STKc_NLK	cd07853	1022	1354	0.00054
NP_000199	STKc_MPK1	cd07857	1022	1327	4.3e-05
NP_000199	STKc_CDK2_3	cd07860	1022	1322	0.0001
NP_000199	STKc_CDK1_euk	cd07861	1022	1322	0.00033
NP_000199	STKc_CDK4	cd07863	1022	1322	4.4e-06
NP_000199	STKc_Nek	cd08215	1022	1292	7.2e-14
NP_000199	STKc_Nek1	cd08218	1022	1290	6.9e-06
NP_000199	STKc_Nek2	cd08217	1022	1292	1.9e-09
NP_000199	STKc_Nek3	cd08219	1022	1289	8.3e-09
NP_000199	STKc_Nek8	cd08220	1022	1295	3.4e-05
NP_000199	STKc_Nek9	cd08221	1022	1291	4.3e-06
NP_000199	STKc_Nek11	cd08222	1022	1295	1.7e-06
NP_000199	STKc_Nek4	cd08223	1022	1294	2.1e-05
NP_000199	STKc_Nek5	cd08225	1022	1295	4.8e-05
NP_000199	STKc_Nek10	cd08528	1022	1292	4.5e-07
NP_000199	STKc_CNK2-like	cd08530	1022	1290	1.3e-08
NP_000199	PTKc_Axl_like	cd05035	1023	1294	2.5e-82
NP_000199	PTKc_Tyro3	cd05074	1023	1294	1.6e-73
NP_000199	PTKc_Axl	cd05075	1023	1294	1.6e-67
NP_000199	PTKc_Tyk2_rpt2	cd05080	1023	1295	5.8e-28
NP_000199	STKc_PKN	cd05589	1023	1345	6.3e-05
NP_000199	STKc_CDK1_like	cd07835	1023	1321	2e-06
NP_000199	STKc_CMGC	cd05118	1024	1298	7.1e-09
NP_000199	STKc_Yank1	cd05578	1024	1298	4.4e-06
NP_000199	STKc_NAK1_like	cd06917	1024	1291	3.3e-05
NP_000199	STKc_CDK_like	cd07829	1024	1298	1.6e-11
NP_000199	STKc_MAK_like	cd07830	1024	1284	5.5e-09
NP_000199	PK_STRAD	cd08216	1024	1296	0.001
NP_000199	STKc_PDK1	cd05581	1025	1304	8e-12
NP_000199	STKc_CRIK	cd05601	1025	1354	0.00088
NP_000199	STKc_MEKK4	cd06626	1025	1295	6.2e-06
NP_000199	STKc_MOK	cd07831	1025	1298	4.1e-06
NP_000199	STKc_CDK9_like	cd07840	1025	1283	3.6e-06
NP_000199	STKc_CDK4_6_like	cd07838	1025	1284	9.9e-09
NP_000199	STKc_FA2-like	cd08529	1025	1298	5.2e-11
NP_000199	STKc_RSK_N	cd05582	1026	1358	1.4e-05
NP_000199	STKc_MAPK4_6	cd07854	1026	1340	0.00044
NP_000199	PTKc	cd00192	1027	1291	2.9e-147
NP_000199	PTK_Jak_rpt1	cd05037	1027	1291	1e-11
NP_000199	PTKc_Ack_like	cd05040	1027	1292	3.4e-57
NP_000199	PTKc_Aatyk	cd05042	1027	1292	1.1e-40
NP_000199	PTKc_Fes_like	cd05041	1027	1292	3e-62
NP_000199	PTKc_c-ros	cd05044	1027	1292	8.2e-112
NP_000199	PTKc_Met_Ron	cd05058	1027	1296	1.4e-76
NP_000199	PTKc_Syk_like	cd05060	1027	1295	9.2e-68
NP_000199	PTK_Tyk2_rpt1	cd05076	1027	1291	2.8e-07
NP_000199	PTK_Jak1_rpt1	cd05077	1027	1291	1.8e-10
NP_000199	PTK_Jak2_Jak3_rpt1	cd05078	1027	1291	9.1e-13
NP_000199	PTKc_Fes	cd05084	1027	1292	4.7e-69
NP_000199	PTKc_Aatyk2	cd05086	1027	1292	1.3e-39
NP_000199	PTKc_Aatyk1_Aatyk3	cd05087	1027	1292	2.1e-51
NP_000199	PTKc_Syk	cd05116	1027	1295	7.6e-49
NP_000199	STKc_PKC	cd05570	1027	1327	4.6e-06
NP_000199	STKc_PKB	cd05571	1027	1354	2e-05
NP_000199	STKc_nPKC_eta	cd05590	1027	1365	0.00074
NP_000199	STKc_PKB_gamma	cd05593	1027	1338	0.0005
NP_000199	STKc_nPKC_epsilon	cd05591	1027	1365	0.00013
NP_000199	STKc_nPKC_theta_delt	cd05592	1027	1366	1e-05
NP_000199	STKc_nPKC_theta	cd05619	1027	1366	1.3e-05
NP_000199	STKc_MEKK1	cd06630	1027	1299	7.2e-08
NP_000199	STKc_MEKK1_plant	cd06632	1027	1284	5.3e-09
NP_000199	PTKc_Zap-70	cd05115	1028	1295	5e-44
NP_000199	STKc_MAPKKK_Bck1_lik	cd06629	1028	1284	2.6e-08
NP_000199	PKc	cd00180	1029	1290	1.7e-65
NP_000199	PTKc_Tie	cd05047	1029	1295	2e-47
NP_000199	PTKc_Fer	cd05085	1029	1292	3.4e-64
NP_000199	STKc_AGC	cd05123	1029	1298	2.7e-07
NP_000199	STKc_cGK_PKG	cd05572	1029	1291	8.5e-06
NP_000199	STKc_GRK	cd05577	1029	1313	9.9e-07
NP_000199	STKc_MAST_like	cd05579	1029	1303	4.5e-05
NP_000199	STKc_beta_ARK	cd05606	1029	1318	5.4e-05
NP_000199	STKc_GRK7	cd05607	1029	1318	6.2e-05
NP_000199	STKc_GRK1	cd05608	1029	1316	1.3e-07
NP_000199	STKc_YSK4	cd06631	1029	1295	2.1e-08
NP_000199	Recep_L_domain	pfam01030	52	164	1.9e-44
NP_000199	Furin-like	pfam00757	179	340	1.9e-81
NP_000199	Recep_L_domain	pfam01030	359	474	7.1e-48
NP_000199	Pkinase	pfam00069	1023	1290	1e-35
NP_000199	FU	smart00261	225	274	3.2e-12
NP_000199	FN3	smart00060	850	934	1.3e-07
NP_000199	Pkinase_Tyr	pfam07714	1023	1290	7.6e-155
NP_000199	TyrKc	smart00219	1023	1290	6.1e-140
NP_000199	STYKc	smart00221	1023	1298	1.5e-51
NP_000199	S_TKc	smart00220	1033	1298	1.8e-44

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258