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Results for Proteins associated with the Gene: MLH1
MLH1
4292


Known Diseases associated with this Protein:
  COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2
  COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 2, INCLUDED
  COLORECTAL CANCER, SPORADIC, SUSCEPTIBILITY TO
  HEREDITARY NON-POLYPOSIS COLORECTAL CANCER 2 (HNPCC2)
  MISMATCH REPAIR CANCER SYNDROME
  MISMATCH REPAIR CANCER SYNDROME (MMRCS)
  MISMATCH REPAIR CANCER SYNDROME, INCLUDED
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE
132
80
65
8
139
Tips:
 The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.
 Clicking a check box on the left will display or hide the corresponding domain(s).
 To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.


Default View:



Swiss-Prot Protein: P40692
Identical to: NP_000240
   Default View:

Default View:

MutL - COG0323
HATPase_c - cd00075
MutL_Trans_MLH3 - cd03486
MutL_Trans_hPMS_1_li - cd03485
MutL_Trans_hPMS_2_li - cd03484
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
TopoII_MutL_Trans - cd00329
DNA_mis_repair - pfam01119
MutL_Trans_MutL - cd03482


RefSeq Protein: NP_000240
   Default View:










Default View:

DNA_mis_repair - pfam01119
TopoII_MutL_Trans - cd00329
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
MutL_Trans_MutL - cd03482
MutL_Trans_hPMS_2_li - cd03484



Default View:

DNA_mis_repair - pfam01119
TopoII_MutL_Trans - cd00329
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
MutL_Trans_MutL - cd03482
MutL_Trans_hPMS_2_li - cd03484



Default View:

MutL - COG0323
MutL_Trans_MLH3 - cd03486
MutL_Trans_hPMS_2_li - cd03484
MutL_Trans_hPMS_1_li - cd03485
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
TopoII_MutL_Trans - cd00329
DNA_mis_repair - pfam01119
MutL_Trans_MutL - cd03482



Default View:

DNA_mis_repair - pfam01119
TopoII_MutL_Trans - cd00329
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
MutL_Trans_MutL - cd03482
MutL_Trans_hPMS_2_li - cd03484



Default View:

DNA_mis_repair - pfam01119
TopoII_MutL_Trans - cd00329
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
MutL_Trans_MutL - cd03482
MutL_Trans_hPMS_2_li - cd03484



Default View:

MutL - COG0323
HATPase_c - cd00075
MutL_Trans_MLH3 - cd03486
MutL_Trans_hPMS_1_li - cd03485
MutL_Trans_hPMS_2_li - cd03484
MutL_Trans_MLH1 - cd03483
MutL_Trans - cd00782
TopoII_MutL_Trans - cd00329
DNA_mis_repair - pfam01119
MutL_Trans_MutL - cd03482




Domains found on the Proteins

Protein ↕Domain ↕Domain Accession ↕Start ↕End ↕E-Value ↕
P40692NO_DOMAIN_FOUND00
NP_000240MutLCOG032357561.4e-112
NP_000240HATPase_ccd00075281542.7e-18
NP_000240MutL_Trans_MLH1cd034832113356.4e-90
NP_000240MutL_Trans_hPMS_2_licd034842113352.7e-10
NP_000240MutL_Trans_hPMS_1_licd034852113353.4e-06
NP_000240MutL_Trans_MLH3cd034862113350.0004
NP_000240TopoII_MutL_Transcd003292123156.7e-29
NP_000240MutL_Transcd007822123349.5e-49
NP_000240MutL_Trans_MutLcd034822163355.9e-07
NP_000240DNA_mis_repairpfam011192163341.9e-47
NP_001161091TopoII_MutL_Transcd003291741.1e-06
NP_001161091MutL_Transcd007821934.6e-24
NP_001161091MutL_Trans_MLH1cd034831941.6e-55
NP_001161091MutL_Trans_MutLcd034822940.0003
NP_001161091MutL_Trans_hPMS_2_licd034846946.4e-05
NP_001161091DNA_mis_repairpfam011191932.7e-19
NP_001161090TopoII_MutL_Transcd003291741.1e-06
NP_001161090MutL_Transcd007821934.6e-24
NP_001161090MutL_Trans_MLH1cd034831941.6e-55
NP_001161090MutL_Trans_MutLcd034822940.0003
NP_001161090MutL_Trans_hPMS_2_licd034846946.4e-05
NP_001161090DNA_mis_repairpfam011191932.7e-19
NP_001161089MutLCOG032316582.4e-12
NP_001161089MutL_Trans_MLH1cd034831132376.4e-90
NP_001161089MutL_Trans_hPMS_1_licd034851132373.4e-06
NP_001161089MutL_Trans_MLH3cd034861132370.0004
NP_001161089MutL_Trans_hPMS_2_licd034841132372.7e-10
NP_001161089TopoII_MutL_Transcd003291142176.7e-29
NP_001161089MutL_Transcd007821142369.5e-49
NP_001161089MutL_Trans_MutLcd034821182375.9e-07
NP_001161089DNA_mis_repairpfam011191182361.9e-47
NP_001245203TopoII_MutL_Transcd003291741.1e-06
NP_001245203MutL_Transcd007821934.6e-24
NP_001245203MutL_Trans_MLH1cd034831941.6e-55
NP_001245203MutL_Trans_MutLcd034822940.0003
NP_001245203MutL_Trans_hPMS_2_licd034846946.4e-05
NP_001245203DNA_mis_repairpfam011191932.7e-19
NP_001245202TopoII_MutL_Transcd003291741.1e-06
NP_001245202MutL_Transcd007821934.6e-24
NP_001245202MutL_Trans_MLH1cd034831941.6e-55
NP_001245202MutL_Trans_MutLcd034822940.0003
NP_001245202MutL_Trans_hPMS_2_licd034846946.4e-05
NP_001245202DNA_mis_repairpfam011191932.7e-19
NP_001245200MutLCOG032356877.7e-114
NP_001245200HATPase_ccd00075281542.7e-18
NP_001245200MutL_Trans_MLH1cd034832113356.4e-90
NP_001245200MutL_Trans_hPMS_2_licd034842113352.7e-10
NP_001245200MutL_Trans_hPMS_1_licd034852113353.4e-06
NP_001245200MutL_Trans_MLH3cd034862113350.0004
NP_001245200TopoII_MutL_Transcd003292123156.7e-29
NP_001245200MutL_Transcd007822123349.5e-49
NP_001245200MutL_Trans_MutLcd034822163355.9e-07
NP_001245200DNA_mis_repairpfam011192163341.9e-47



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