Results for the gene: STK11

Results for Proteins associated with the Gene: STK11

STK11

6794

Q15831 NP_000446

NCBI

Known Diseases associated with this Protein:

MELANOMA, MALIGNANT, SOMATIC

PANCREATIC CANCER, SOMATIC

PEUTZ-JEGHERS SYNDROME

PEUTZ-JEGHERS SYNDROME (PJS)

TESTICULAR GERM CELL TUMOR (TGCT)

TESTICULAR TUMOR, SOMATIC

			20 37 13 1 43

Tips:

The Domains on the Default View are decided by HMMER's search E-Value of the Protein against the Domain model.

Clicking a check box on the left will display or hide the corresponding domain(s).

To view the Protein page, either click on the protein links in the box to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q15831

Identical to: NP_000446

Default View:

RefSeq Protein: NP_000446

Default View:

Domains found on the Proteins

Protein ↕	Domain ↕	Domain Accession ↕	Start ↕	End ↕	E-Value ↕
NP_000446	STKc_ROCK2	cd05621	2	383	2.2e-08
NP_000446	STKc_ROCK1	cd05622	2	382	4.7e-07
NP_000446	STKc_PAK5	cd06658	19	327	1.3e-05
NP_000446	STKc_PAK6	cd06659	20	337	1.3e-08
NP_000446	STKc_PAK_I	cd06647	23	330	9.1e-09
NP_000446	STKc_PAK3	cd06656	23	333	7.3e-08
NP_000446	STKc_PAK4	cd06657	24	333	8.7e-06
NP_000446	STKc_p38	cd07851	26	342	3.2e-09
NP_000446	STKc_JNK3	cd07874	27	367	9.5e-07
NP_000446	STKc_JNK2	cd07876	27	350	7.7e-08
NP_000446	PTKc_FGFR1	cd05098	29	313	2.6e-05
NP_000446	PTKc_FGFR4	cd05099	29	327	9.5e-06
NP_000446	STKc_PAK_II	cd06648	30	323	4.5e-09
NP_000446	STKc_ERK5	cd07855	30	347	2.7e-11
NP_000446	PTKc_FGFR2	cd05101	31	318	2.8e-05
NP_000446	STKc_TAO3	cd06633	31	355	1.1e-05
NP_000446	STKc_PAK1	cd06654	31	331	8.3e-08
NP_000446	STKc_ASK	cd06624	32	309	6.2e-12
NP_000446	STKc_MAP4K4_6	cd06636	32	309	0.00014
NP_000446	STKc_PAK2	cd06655	32	333	8.2e-08
NP_000446	STKc_JNK	cd07850	32	349	3.4e-06
NP_000446	STKc_p38alpha_MAPK14	cd07877	33	342	1e-06
NP_000446	STKc_PAK	cd06614	35	322	2.5e-16
NP_000446	STKc_myosinIIIB	cd06639	35	310	5.7e-07
NP_000446	STKc_p38delta_MAPK13	cd07879	35	381	6.4e-05
NP_000446	STKc_p38gamma_MAPK12	cd07880	35	381	3.6e-07
NP_000446	STKc_p38beta_MAPK11	cd07878	35	342	6.5e-07
NP_000446	PTK_CCK4	cd05046	36	291	0.00076
NP_000446	PTKc_FAK	cd05056	36	308	3.3e-09
NP_000446	PTKc_Lck_Blk	cd05067	36	309	0.00026
NP_000446	PTKc_Frk_like	cd05068	36	308	5e-09
NP_000446	PTKc_Fyn_Yrk	cd05070	36	308	9.2e-06
NP_000446	PTKc_Lyn	cd05072	36	308	4.2e-06
NP_000446	PTKc_Hck	cd05073	36	309	6.1e-05
NP_000446	STKc_STK10_LOK	cd06644	36	322	6.7e-09
NP_000446	STKc_CDK9	cd07865	36	309	6.8e-10
NP_000446	PKc_MKK7	cd06618	37	325	1.2e-07
NP_000446	STKc_STK25-YSK1	cd06642	37	333	5.5e-07
NP_000446	STKc_JNK1	cd07875	37	357	9.6e-07
NP_000446	PTKc_FGFR3	cd05100	38	365	0.00027
NP_000446	STKc_TAO1	cd06635	38	347	2.3e-06
NP_000446	PTKc_TrkB	cd05093	39	319	4.6e-05
NP_000446	PTKc_Btk_Bmx	cd05113	39	308	4.7e-06
NP_000446	STKc_TAO	cd06607	39	355	8e-07
NP_000446	STKc_TAO2	cd06634	39	350	1.2e-07
NP_000446	STKc_MAP4K5	cd06646	39	308	1.5e-07
NP_000446	PTKc_Src_like	cd05034	40	308	9.6e-09
NP_000446	PTKc_InsR_like	cd05032	41	305	1.2e-06
NP_000446	PTKc_Trk	cd05049	41	311	2.5e-06
NP_000446	PTKc_FGFR	cd05053	41	307	5.1e-05
NP_000446	PTKc_EGFR_like	cd05057	41	301	0.00082
NP_000446	PTKc_EphR_A10	cd05064	41	313	0.00096
NP_000446	PTKc_TrkA	cd05092	41	311	3.8e-05
NP_000446	STKc_phototropin_lik	cd05574	41	328	1.2e-11
NP_000446	STKc_MST4	cd06640	41	333	1.3e-06
NP_000446	STKc_MAP4K3	cd06645	41	308	7.7e-07
NP_000446	STKc_CDK10	cd07845	41	326	9.7e-15
NP_000446	PTKc_Ror1	cd05090	42	308	1.6e-06
NP_000446	PTKc_Ror2	cd05091	42	308	3.5e-06
NP_000446	PTKc_EGFR	cd05108	42	362	0.00013
NP_000446	STKc_TNIK	cd06637	42	309	7.5e-06
NP_000446	PTKc_Csk	cd05082	43	307	1.2e-05
NP_000446	STKc_myosinIIIA	cd06638	43	309	1.4e-07
NP_000446	STKc_ERK1_2_like	cd07849	43	350	3.1e-09
NP_000446	STKc_MAPK4_6	cd07854	43	350	1.2e-06
NP_000446	STKc_TEY_MAPK_plant	cd07858	43	381	9e-12
NP_000446	STKc_CDK12	cd07864	43	309	5.7e-14
NP_000446	PTKc_ALK_LTK	cd05036	44	309	3.1e-06
NP_000446	PTKc_Met_Ron	cd05058	44	313	2.2e-05
NP_000446	PTKc_Yes	cd05069	44	312	2.5e-06
NP_000446	PTKc_Src	cd05071	44	310	6.5e-06
NP_000446	PTKc_DDR2	cd05095	44	311	0.00052
NP_000446	STKc_BUR1	cd07866	44	309	6.4e-13
NP_000446	STKc_MAP4K3_like	cd06613	45	308	1.5e-13
NP_000446	STKc_PCTAIRE_like	cd07844	45	309	2.2e-13
NP_000446	STKc_Sty1_Hog1	cd07856	45	339	9.1e-09
NP_000446	PTKc_EphR_B	cd05065	46	313	0.001
NP_000446	PTKc_Jak1_rpt2	cd05079	46	313	5.4e-06
NP_000446	PTKc_Chk	cd05083	46	312	1.6e-07
NP_000446	STKc_PFTAIRE1	cd07869	46	358	1.9e-05
NP_000446	STKc_PFTAIRE2	cd07870	46	341	1.6e-08
NP_000446	STKc_PCTAIRE3	cd07871	46	309	3.2e-09
NP_000446	STKc_PCTAIRE2	cd07872	46	330	2.6e-07
NP_000446	STKc_PCTAIRE1	cd07873	46	324	2.5e-07
NP_000446	STKc_Nek6_Nek7	cd08224	46	312	2.7e-11
NP_000446	STKc_Nek6	cd08228	46	312	4.1e-09
NP_000446	STKc_Nek7	cd08229	46	314	7.6e-11
NP_000446	PTKc_Abl	cd05052	47	313	3e-08
NP_000446	PTKc_InsR	cd05061	47	322	0.00016
NP_000446	PTKc_IGF-1R	cd05062	47	305	4.2e-05
NP_000446	PTKc_DDR_like	cd05097	47	311	0.00017
NP_000446	PTKc_Tec_Rlk	cd05114	47	308	2.6e-05
NP_000446	PTKc_Itk	cd05112	47	307	3e-05
NP_000446	STKc_ROCK_NDR_like	cd05573	47	365	6.8e-11
NP_000446	STKc_PKA	cd05580	47	357	3.4e-14
NP_000446	STKc_DMPK_like	cd05597	47	395	5.7e-07
NP_000446	STKc_LATS	cd05598	47	386	0.0001
NP_000446	STKc_MAST	cd05609	47	364	2.9e-10
NP_000446	STKc_PRKX_like	cd05612	47	333	1.2e-10
NP_000446	STKc_MRCK_alpha	cd05623	47	396	3.2e-06
NP_000446	STKc_MRCK_beta	cd05624	47	395	2e-06
NP_000446	STKc_LATS1	cd05625	47	386	0.0007
NP_000446	STKc_NDR1	cd05628	47	367	0.00031
NP_000446	STKc_myosinIII_like	cd06608	47	309	2.6e-09
NP_000446	STKc_OSR1_SPAK	cd06610	47	309	2.9e-10
NP_000446	PKc_MKK5	cd06619	47	345	0.00019
NP_000446	PKc_MAPKK_Pek1_like	cd06621	47	321	2.6e-09
NP_000446	PKc_MAPKK_PBS2_like	cd06622	47	344	1.9e-07
NP_000446	STKc_MST3_like	cd06609	47	333	4.2e-10
NP_000446	STKc_MST3	cd06641	47	333	1.3e-06
NP_000446	STKc_MEKK2	cd06652	47	310	7.9e-08
NP_000446	STKc_NAK1_like	cd06917	47	312	6.4e-10
NP_000446	STKc_CDKL	cd07833	47	309	8.2e-13
NP_000446	STKc_CdkB_plant	cd07837	47	310	7.1e-14
NP_000446	STKc_CDKL1_4	cd07847	47	341	1e-09
NP_000446	STKc_CDKL2_3	cd07846	47	309	3.5e-10
NP_000446	STKc_CDKL5	cd07848	47	309	7.3e-07
NP_000446	STKc_CDK6	cd07862	47	309	1e-05
NP_000446	SPS1	COG0515	47	430	5.6e-52
NP_000446	PTKc_RET	cd05045	48	312	2.5e-05
NP_000446	PTKc_Ror	cd05048	48	308	2.2e-07
NP_000446	PTKc_Tyk2_rpt2	cd05080	48	314	4.6e-08
NP_000446	PTKc_Jak2_Jak3_rpt2	cd05081	48	310	3.8e-07
NP_000446	PTKc_Musk	cd05050	48	306	4.7e-06
NP_000446	PKc_STE	cd05122	48	308	1.1e-17
NP_000446	STKc_MSK_N	cd05583	48	326	3.2e-09
NP_000446	STKc_cPKC	cd05587	48	368	1.1e-12
NP_000446	STKc_Yank1	cd05578	48	309	1.7e-15
NP_000446	STKc_GRK4_like	cd05605	48	328	2.2e-09
NP_000446	STKc_MSK1_N	cd05613	48	326	1.1e-08
NP_000446	STKc_cPKC_alpha	cd05615	48	361	1.1e-09
NP_000446	STKc_cPKC_beta	cd05616	48	368	2e-08
NP_000446	STKc_GRK6	cd05630	48	328	1.6e-06
NP_000446	STKc_GRK4	cd05631	48	328	2.7e-06
NP_000446	STKc_GRK5	cd05632	48	328	2.1e-06
NP_000446	STKc_MSK2_N	cd05614	48	369	9.4e-09
NP_000446	STKc_MAPKKK	cd06606	48	309	2.9e-31
NP_000446	PKc_MAPKK_plant_like	cd06623	48	316	2e-15
NP_000446	STKc_MAPKKK_Byr2_lik	cd06628	48	309	1.4e-22
NP_000446	STKc_Cdc7_like	cd06627	48	309	1.8e-16
NP_000446	STKc_MAPKKK_Bck1_lik	cd06629	48	309	9.2e-11
NP_000446	STKc_YSK4	cd06631	48	309	2.1e-10
NP_000446	STKc_MEKK1_plant	cd06632	48	309	5.9e-14
NP_000446	STKc_MEKK1	cd06630	48	310	3.6e-09
NP_000446	STKc_MEKK3	cd06651	48	311	4.6e-10
NP_000446	STKc_MEKK3_like_1	cd06653	48	316	1.4e-08
NP_000446	STKc_MAPK	cd07834	48	339	1.6e-12
NP_000446	STKc_Pho85	cd07836	48	309	1.8e-15
NP_000446	STKc_CDK5	cd07839	48	309	9e-12
NP_000446	STKc_CDK7	cd07841	48	326	7.7e-15
NP_000446	STKc_CDK8_like	cd07842	48	309	4.5e-11
NP_000446	STKc_CCRK	cd07832	48	310	3.7e-15
NP_000446	STKc_MPK1	cd07857	48	343	5.2e-10
NP_000446	STKc_TDY_MAPK_plant	cd07859	48	382	1.7e-07
NP_000446	STKc_CDK2_3	cd07860	48	309	1.2e-19
NP_000446	STKc_CDK1_euk	cd07861	48	309	1.4e-15
NP_000446	STKc_CDK4	cd07863	48	309	4.5e-09
NP_000446	STKc_Nek	cd08215	48	309	1.9e-25
NP_000446	STKc_Nek2	cd08217	48	309	1.2e-13
NP_000446	STKc_Nek1	cd08218	48	309	7.4e-27
NP_000446	STKc_Nek3	cd08219	48	309	4.1e-19
NP_000446	STKc_Nek8	cd08220	48	309	6.2e-09
NP_000446	STKc_Nek9	cd08221	48	309	3.8e-09
NP_000446	STKc_Nek11	cd08222	48	309	1.1e-18
NP_000446	STKc_Nek4	cd08223	48	309	3.3e-20
NP_000446	STKc_Nek5	cd08225	48	309	2.3e-20
NP_000446	STKc_Nek10	cd08528	48	309	4.8e-07
NP_000446	STKc_CNK2-like	cd08530	48	309	2.9e-13
NP_000446	STKc_FA2-like	cd08529	48	309	7.6e-12
NP_000446	PTKc_Jak_rpt2	cd05038	49	307	5.9e-08
NP_000446	PTKc_Axl_like	cd05035	49	310	5.3e-05
NP_000446	PTKc_Tyro3	cd05074	49	311	1.3e-05
NP_000446	PTKc_Axl	cd05075	49	311	0.00057
NP_000446	STKc_CMGC	cd05118	49	309	6.3e-16
NP_000446	PTKc_Srm_Brk	cd05148	49	308	1.4e-09
NP_000446	STKc_PDK1	cd05581	49	309	9e-25
NP_000446	STKc_PKN	cd05589	49	367	5.2e-09
NP_000446	STKc_CRIK	cd05601	49	356	1.3e-08
NP_000446	STKc_MST1_2	cd06612	49	309	8.2e-14
NP_000446	PKc_MKK4	cd06616	49	323	4.8e-06
NP_000446	STKc_MEKK3_like	cd06625	49	309	1.1e-14
NP_000446	STKc_CDK_like	cd07829	49	309	6.7e-20
NP_000446	STKc_MAK_like	cd07830	49	309	1.1e-15
NP_000446	STKc_MOK	cd07831	49	309	1.9e-13
NP_000446	STKc_CDK1_like	cd07835	49	309	8e-20
NP_000446	STKc_CDK4_6_like	cd07838	49	309	2e-13
NP_000446	STKc_CDK9_like	cd07840	49	309	2.5e-17
NP_000446	PTKc_Csk_like	cd05039	50	309	0.00015
NP_000446	STKc_SLK_like	cd06611	50	317	1.5e-10
NP_000446	STKc_SLK	cd06643	50	320	1.1e-09
NP_000446	STKc_CDC2L6	cd07867	50	346	3.2e-05
NP_000446	STKc_CDK8	cd07868	50	309	0.00017
NP_000446	STKc_p70S6K	cd05584	52	369	2.4e-09
NP_000446	PKc_MAPKK	cd06605	52	315	1.7e-10
NP_000446	PKc_MKK3_6	cd06617	52	324	1.5e-08
NP_000446	PKc_MEK	cd06615	52	337	2.2e-05
NP_000446	STKc_MEKK4	cd06626	52	309	5.1e-15
NP_000446	PTKc	cd00192	53	308	1.1e-11
NP_000446	PTK_Jak_rpt1	cd05037	53	307	0.00023
NP_000446	PTKc_Ack_like	cd05040	53	309	1.7e-12
NP_000446	PTKc_Fes_like	cd05041	53	309	5.9e-08
NP_000446	PTKc_Aatyk	cd05042	53	326	0.00048
NP_000446	PTKc_c-ros	cd05044	53	307	9.5e-05
NP_000446	PTKc_Tie	cd05047	53	313	0.001
NP_000446	PTKc_Syk_like	cd05060	53	305	1.3e-06
NP_000446	PTKc_Fes	cd05084	53	309	3.1e-07
NP_000446	PTKc_Fer	cd05085	53	309	4.8e-06
NP_000446	PTKc_Syk	cd05116	53	310	1.4e-06
NP_000446	STKc_PKC	cd05570	53	363	4.9e-13
NP_000446	STKc_PKB	cd05571	53	382	2.6e-12
NP_000446	STKc_SGK	cd05575	53	385	4e-08
NP_000446	STKc_RSK_N	cd05582	53	389	1.3e-06
NP_000446	STKc_aPKC	cd05588	53	373	1.3e-08
NP_000446	STKc_nPKC_eta	cd05590	53	368	1.7e-09
NP_000446	STKc_nPKC_epsilon	cd05591	53	373	1.2e-10
NP_000446	STKc_PKB_gamma	cd05593	53	396	5.6e-10
NP_000446	STKc_PKB_alpha	cd05594	53	395	8e-11
NP_000446	STKc_PKB_beta	cd05595	53	371	8.9e-09
NP_000446	STKc_SGK1	cd05602	53	374	2.9e-06
NP_000446	STKc_SGK3	cd05604	53	369	6e-06
NP_000446	STKc_nPKC_theta_delt	cd05592	53	369	3.9e-14
NP_000446	STKc_SGK2	cd05603	53	393	2.1e-09
NP_000446	STKc_aPKC_zeta	cd05617	53	369	2.2e-08
NP_000446	STKc_aPKC_iota	cd05618	53	384	1.5e-06
NP_000446	STKc_nPKC_theta	cd05619	53	369	3.5e-11
NP_000446	STKc_nPKC_delta	cd05620	53	369	5.3e-07
NP_000446	PKc_MAPKK_Byr1_like	cd06620	53	333	6.2e-06
NP_000446	STKc_CDC2L1	cd07843	53	309	1.6e-10
NP_000446	STKc_beta_ARK	cd05606	54	324	6.6e-07
NP_000446	STKc_GRK3	cd05633	54	321	1.2e-05
NP_000446	PKc	cd00180	55	307	4.5e-73
NP_000446	PTKc_Tec_like	cd05059	55	290	3e-06
NP_000446	PTKc_Zap-70	cd05115	55	312	1.5e-06
NP_000446	STKc_AGC	cd05123	55	309	1.2e-23
NP_000446	STKc_cGK_PKG	cd05572	55	312	2.1e-12
NP_000446	STKc_GRK	cd05577	55	327	3e-10
NP_000446	STKc_MAST_like	cd05579	55	314	4e-16
NP_000446	STKc_YPK1_like	cd05585	55	390	1.9e-09
NP_000446	STKc_Sck1_like	cd05586	55	433	4.7e-08
NP_000446	STKc_Sid2p_Dbf2p	cd05600	55	388	6.5e-07
NP_000446	STKc_GRK7	cd05607	55	327	1.7e-06
NP_000446	STKc_GRK1	cd05608	55	327	1.4e-11
NP_000446	STKc_NLK	cd07853	55	382	1.3e-07
NP_000446	STKc_NDR_like	cd05599	56	367	4.4e-05
NP_000446	STKc_Rim15_like	cd05611	58	311	0.00032
NP_000446	STKc_MAPK15	cd07852	78	348	2.6e-10
NP_000446	Pkinase	pfam00069	49	309	1.4e-63
NP_000446	Pkinase_Tyr	pfam07714	49	307	3.7e-16
NP_000446	TyrKc	smart00219	49	309	2.6e-14
NP_000446	STYKc	smart00221	49	309	5e-72
NP_000446	S_TKc	smart00220	59	309	1.8e-79

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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