Results for the protein: P01019

Results for the Protein: P01019

113880

183

AGT

NCBI, UniProt

ANGT_HUMAN RecName: Full=Angiotensinogen; AltName: Full=Serpin A8; Contains: RecName: Full=Angiotensin-1; AltName: Full=Angiotensin 1-10; AltName: Full=Angiotensin I; Short=Ang I; Contains: RecName: Full=Angiotensin-2; AltName: Full=Angiotensin 1-8; AltName: Full=Angiotensin II; Short=Ang II; Contains: RecName: Full=Angiotensin-3; AltName: Full=Angiotensin 2-8; AltName: Full=Angiotensin III; Short=Ang III; AltName: Full=Des-Asp[1]-angiotensin II; Contains: RecName: Full=Angiotensin-4; AltName: Full=Angiotensin 3-8; AltName: Full=Angiotensin IV; Short=Ang IV; Contains: RecName: Full=Angiotensin 1-9; Contains: RecName: Full=Angiotensin 1-7; Contains: RecName: Full=Angiotensin 1-5; Contains: RecName: Full=Angiotensin 1-4; Flags: Precursor

Known Diseases associated with this Protein:
  HYPERTENSION, ESSENTIAL, SUSCEPTIBILITY TO
  IGA NEPHROPATHY, PROGRESSION TO
  PREECLAMPSIA, SUSCEPTIBILITY TO, INCLUDED;;
  RENAL TUBULAR DYSGENESIS
  RENAL TUBULAR DYSGENESIS (RTD)

4

12

3

2

11

Tips:

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To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: HCII - cd02047 COG4826 - COG4826 PEDF - cd02052 PAI-1_nexin-1 - cd02051 hsp47 - cd02046 PZI - cd02055 bacterial_SERPIN - cd02049 ovalbumin_like - cd02059 angiotensinogen - cd02054 Serpin - pfam00079 C1_inh - cd02050 alpha-1-antitrypsin_ - cd02056 SERPIN - cd00172 alpha2AP - cd02053 plant_SERPIN - cd02043 SERPIN - smart00093 ov-serpin - cd02044	Swiss-Prot Protein: P01019 Identical to: NP_000020 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PEDF	cd02052	0.00019	95	481
PAI-1_nexin-1	cd02051	1.1e-06	100	481
hsp47	cd02046	1.1e-05	103	478
PZI	cd02055	6.3e-05	104	478
bacterial_SERPIN	cd02049	0.0008	105	478
angiotensinogen	cd02054	2.2e-274	105	481
ovalbumin_like	cd02059	0.00026	105	481
C1_inh	cd02050	0.00059	108	478
alpha-1-antitrypsin_	cd02056	1.5e-08	108	478
SERPIN	cd00172	6.2e-16	109	478
alpha2AP	cd02053	7.2e-06	113	478
plant_SERPIN	cd02043	0.00019	115	481
ov-serpin	cd02044	1.4e-05	118	481
COG4826	COG4826	0.00088	63	485
Serpin	pfam00079	1e-56	108	481
SERPIN	smart00093	5.4e-100	115	481

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_035433	Disease	p.ARG375GLN	Renal tubular dysgenesis (RTD)
Swiss-Prot	VAR_029166	Polymorphism	p.GLU98LYS	N/A
Swiss-Prot	VAR_051939	Polymorphism	p.GLY114CYS	N/A
Swiss-Prot	VAR_007095	Polymorphism	p.LEU244ARG	N/A
Swiss-Prot	VAR_014573	Polymorphism	p.LEU392MET	N/A
Swiss-Prot	VAR_022933	Polymorphism	p.LEU43PHE	N/A
Swiss-Prot	VAR_029167	Polymorphism	p.MET268ILE	N/A
dbSNP	rs699	Polymorphism	p.MET268THR	N/A
Swiss-Prot	VAR_035432	Polymorphism	p.PRO335SER	N/A
Swiss-Prot	VAR_007094	Polymorphism	p.THR242ILE	N/A
Swiss-Prot	VAR_035431	Polymorphism	p.THR137MET	N/A
dbSNP	rs4762	Polymorphism	p.THR207MET	N/A
Swiss-Prot	VAR_007097	Polymorphism	p.TYR281CYS	N/A
OMIM	106150.0003	Disease	p.ARG375GLN	RENAL TUBULAR DYSGENESIS
OMIM	106150.0004	Disease	p.GLU202TER	RENAL TUBULAR DYSGENESIS
OMIM	106150.0001	Disease	p.MET235THR	HYPERTENSION, ESSENTIAL, SUSCEPTIBILITY TO\|\|PREECLAMPSIA, SUSCEPTIBILITY TO, INCLUDED;;\|\|IgA NEPHROPATHY, PROGRESSION TO

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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