Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: P20594
113916

ANPRB_HUMAN RecName: Full=Atrial natriuretic peptide receptor 2; AltName: Full=Atrial natriuretic peptide receptor type B; Short=ANP-B; Short=ANPR-B; Short=NPR-B; AltName: Full=Guanylate cyclase B; Short=GC-B; Flags: Precursor

Known Diseases associated with this Protein:
  ACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE
  ACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE (AMDM)
15
3
4
0
14
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

PBP1_NPR_like - cd06373
PBP1_sensory_GC_DEF_ - cd06371
PBP1_NPR_B - cd06384
PBP1_NPR_C_like - cd06386
Periplasmic_Binding_ - cd01391
PBP1_NPR_GC_like - cd06352
PBP1_NPR_A - cd06385
PBP1_ABC_transporter - cd06268
PBP1_ABC_transporter - cd04509
PBP1_glutamate_recep - cd06269
PBP1_iGluR_N_LIVBP_l - cd06351
PBP1_GPCR_family_C_l - cd06350
PBP1_GABAb_receptor - cd06366
PBP1_Speract_GC_like - cd06370
PBP1_GC_G_like - cd06372
ANF_receptor - pfam01094
PTKc_FAK - cd05056
PTKc_EGFR_like - cd05057
PTKc_PDGFR - cd05055
PTKc_InsR_like - cd05032
STKc_TAO1 - cd06635
PTKc_DDR2 - cd05095
PTKc_DDR - cd05051
PKc_MKK5 - cd06619
PTKc_FGFR1 - cd05098
PTKc_FGFR2 - cd05101
STKc_MEKK3 - cd06651
PTKc_FGFR4 - cd05099
STKc_TAO2 - cd06634
STKc_PAK - cd06614
PTKc_FGFR3 - cd05100
STKc_CDKL2_3 - cd07846
PTK_HER3 - cd05111
PTKc_Musk - cd05050
PTKc_HER4 - cd05110
PTKc_HER2 - cd05109
PTKc_EGFR - cd05108
PTKc_TrkB - cd05093
PTKc_Jak_rpt2 - cd05038
PTKc_TrkA - cd05092
STKc_PAK_II - cd06648
PTKc_DDR_like - cd05097
PTKc_InsR - cd05061
PTK_Jak1_rpt1 - cd05077
PTKc_IGF-1R - cd05062
PTKc_Ror2 - cd05091
PTKc_EphR_A10 - cd05064
PTKc_EphR - cd05033
PTKc_Jak1_rpt2 - cd05079
PTK_CCK4 - cd05046
PTKc_EphR_B - cd05065
TyrKc - smart00219
STKc_Nek10 - cd08528
PTKc_FGFR - cd05053
STYKc - smart00221
STKc_ASK - cd06624
PTKc_RET - cd05045
STKc_Nek11 - cd08222
PTKc_Ror - cd05048
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
PTKc_Chk - cd05083
PK_STRAD - cd08216
PTKc_EphR_A2 - cd05063
PTKc_Met_Ron - cd05058
PKc_STE - cd05122
PKc_MKK7 - cd06618
PTKc_Ack_like - cd05040
Pkinase_Tyr - pfam07714
STKc_YSK4 - cd06631
PTKc_Lyn - cd05072
PTKc_Csk - cd05082
PTKc_Aatyk2 - cd05086
PTKc_Zap-70 - cd05115
PTK_Jak2_Jak3_rpt1 - cd05078
PKc - cd00180
PTKc_Tie - cd05047
STKc_cGK_PKG - cd05572
STKc_MEKK1_plant - cd06632
PTKc_Hck - cd05073
SPS1 - COG0515
PTKc_Abl - cd05052
PTKc_Frk_like - cd05068
PTKc_Fyn_Yrk - cd05070
PTKc_Src - cd05071
PTKc_Yes - cd05069
PTKc_Tec_Rlk - cd05114
PTKc_Lck_Blk - cd05067
PTKc_Itk - cd05112
PTKc_Btk_Bmx - cd05113
STKc_TAO - cd06607
STKc_NAK1_like - cd06917
PTKc_Syk - cd05116
STKc_CDK9 - cd07865
STKc_CdkB_plant - cd07837
STKc_CDKL1_4 - cd07847
STKc_FA2-like - cd08529
STKc_MST1_2 - cd06612
STKc_MEKK3_like - cd06625
S_TKc - smart00220
STKc_MST4 - cd06640
STKc_STK25-YSK1 - cd06642
STKc_CDK5 - cd07839
STKc_MST3 - cd06641
PTKc_Tie2 - cd05088
STKc_CDK10 - cd07845
STKc_MAPKKK_Byr2_lik - cd06628
PKc_MAPKK_plant_like - cd06623
PTKc_Fer - cd05085
PTK_Jak_rpt1 - cd05037
PTKc_Tec_like - cd05059
PTKc_Csk_like - cd05039
PTKc_ALK_LTK - cd05036
PTKc_EphR_A - cd05066
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Fes - cd05084
STKc_CDK12 - cd07864
STKc_Nek6 - cd08228
STKc_NLK - cd07853
STKc_Nek7 - cd08229
PTKc_Syk_like - cd05060
STKc_MAP4K3_like - cd06613
STKc_Nek6_Nek7 - cd08224
STKc_OSR1_SPAK - cd06610
STKc_PDK1 - cd05581
PTKc_Aatyk - cd05042
PTKc_Tyk2_rpt2 - cd05080
PTKc_Tie1 - cd05089
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_CNK2-like - cd08530
STKc_MAPK - cd07834
STKc_CCRK - cd07832
STKc_CDK7 - cd07841
STKc_Nek - cd08215
STKc_Nek2 - cd08217
Pkinase - pfam00069
STKc_CDK9_like - cd07840
STKc_AGC - cd05123
STKc_CMGC - cd05118
PTKc_Src_like - cd05034
STKc_CDK_like - cd07829
PTKc_Trk - cd05049
STKc_MEKK4 - cd06626
STKc_MST3_like - cd06609
PKc_MEK - cd06615
PTKc_c-ros - cd05044
PTKc_Fes_like - cd05041
PTKc - cd00192
STKc_SLK_like - cd06611
PTKc_Srm_Brk - cd05148
STKc_MAST_like - cd05579
PKc_MAPKK_Pek1_like - cd06621
PKc_MAPKK_Byr1_like - cd06620
PKc_MAPKK - cd06605
PTK_Ryk - cd05043
KIND - smart00750
CyaA - COG2114
CYCc - smart00044
Guanylate_cyc - pfam00211
Nucleotidyl_cyc_III - cd07556
CHD - cd07302


Swiss-Prot Protein: P20594
Identical to: NP_003986
   Default View:
















































































































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PBP1_ABC_transportercd045098.1e-7526395
PBP1_ABC_transportercd062680.0001626396
PBP1_glutamate_recepcd062691.4e-2926421
PBP1_GPCR_family_C_lcd063500.0001826418
PBP1_iGluR_N_LIVBP_lcd063510.00126417
PBP1_NPR_GC_likecd063524.8e-14726421
PBP1_sensory_GC_DEF_cd063710.0006626409
PBP1_NPR_likecd063732.2e-22126421
PBP1_NPR_Bcd0638426421
PBP1_NPR_Acd063851.2e-13926427
PBP1_NPR_C_likecd063869.6e-3426422
PBP1_GABAb_receptorcd063662.5e-0727408
PBP1_Speract_GC_likecd063708.7e-0931411
PBP1_GC_G_likecd063726.2e-0835419
PTKc_FAKcd050561.4e-07481794
PTKc_InsR_likecd050322.8e-09492788
PTKc_PDGFRcd050554.5e-05492790
PTKc_EGFR_likecd050573.1e-07492800
PTKc_DDRcd050514.4e-06493788
PTKc_DDR2cd050950.001493788
STKc_TAO1cd066350.00013493836
PTKc_FGFR1cd050980.00028497792
PKc_MKK5cd066190.00032497810
PTKc_FGFR2cd051010.00023498792
STKc_MEKK3cd066510.00021498782
PTKc_FGFR4cd050992.4e-05499811
STKc_TAO2cd066343.9e-05500827
PTKc_FGFR3cd051000.00084504832
STKc_PAKcd066141.9e-07504798
PTK_HER3cd051111.8e-06505800
STKc_CDKL2_3cd078465.1e-05505786
PTKc_Muskcd050504.9e-06506788
PTKc_EGFRcd051085.5e-06506836
PTKc_HER2cd051098.3e-06506800
PTKc_HER4cd051103.2e-05506828
PTKc_Jak_rpt2cd050388.8e-08507790
PTKc_TrkAcd050927.8e-05507792
PTKc_TrkBcd050936e-05507799
PTKc_InsRcd050610.00011508799
PTKc_IGF-1Rcd050628.4e-06508788
PTK_Jak1_rpt1cd050770.00028508787
PTKc_DDR_likecd050976.7e-05508788
STKc_PAK_IIcd066484.9e-06508802
PTKc_EphR_A10cd050642e-06509790
PTKc_Ror2cd050910.00074509789
PTKc_EphRcd050331.3e-07510790
PTK_CCK4cd050463.8e-06511788
PTKc_EphR_Bcd050651.2e-05511790
PTKc_Jak1_rpt2cd050790.00013511789
PTKc_FGFRcd050537.6e-06513791
STKc_ASKcd066240.00027513786
STKc_Nek10cd085280.00036513788
PTKc_RETcd050450.00011514792
PTKc_Rorcd050487.9e-06514789
STKc_Nek11cd082220.00043514786
PTKc_Axl_likecd050353.7e-05515790
PTKc_Tyro3cd050740.00027515790
PTKc_Chkcd050832.2e-07515792
PK_STRADcd082160.00033515805
PTKc_Met_Roncd050589.9e-07516792
PTKc_EphR_A2cd050631.6e-05516790
PKc_STEcd051222.7e-09516785
PKc_MKK7cd066180.00029516818
PTKc_Ack_likecd050404.9e-10517788
PTKc_Lyncd050723.6e-07517789
PTKc_Cskcd050829.5e-08517789
PTKc_Aatyk2cd050860.00086517788
PTKc_Zap-70cd051155.3e-05517791
STKc_YSK4cd066310.00013517786
PTK_Jak2_Jak3_rpt1cd050780.00012518790
PKccd001802.6e-48519786
PTKc_Tiecd050470.0005519791
STKc_cGK_PKGcd055720.00036519793
STKc_MEKK1_plantcd066320.00032519786
PTKc_Ablcd050521.9e-10520790
PTKc_Frk_likecd050684.2e-09520789
PTKc_Yescd050692.5e-08520789
PTKc_Fyn_Yrkcd050706.3e-07520789
PTKc_Srccd050711.2e-06520791
PTKc_Hckcd050732.8e-08520789
SPS1COG05152.9e-10520953
PTKc_Lck_Blkcd050676.6e-07521789
PTKc_Itkcd051122.6e-08521787
PTKc_Btk_Bmxcd051132.1e-10521787
PTKc_Tec_Rlkcd051144.2e-09521787
STKc_TAOcd066076.4e-05521826
PTKc_Sykcd051163.4e-05522791
STKc_NAK1_likecd069171.5e-05522806
STKc_CdkB_plantcd078370.00047522790
STKc_CDKL1_4cd078470.00073522786
STKc_CDK9cd078650.00011522779
STKc_MST1_2cd066121.2e-05523780
STKc_MEKK3_likecd066251.4e-05523788
STKc_MST4cd066400.00043523809
STKc_STK25-YSK1cd066426e-05523809
STKc_MST3cd066410.00017523809
STKc_CDK5cd078390.00035523785
STKc_FA2-likecd085292.3e-05523782
PTKc_Tie2cd050886.9e-05524812
PKc_MAPKK_plant_likecd066235.5e-07525791
STKc_MAPKKK_Byr2_likcd066286.2e-06525786
STKc_CDK10cd078454.4e-05525780
PTK_Jak_rpt1cd050377.2e-06526790
PTKc_Csk_likecd050396.7e-10526789
PTKc_Tec_likecd050593.4e-09526787
PTKc_Fercd050852.4e-07526788
PTKc_ALK_LTKcd050364.2e-05527788
PTKc_EphR_Acd050663.3e-05527790
PTKc_Jak2_Jak3_rpt2cd050816.6e-08527790
PTKc_Fescd050844.7e-08528788
PTKc_Aatyk1_Aatyk3cd050870.00078528788
STKc_CDK12cd078641.8e-05528779
STKc_NLKcd078530.00075529860
STKc_Nek6cd082280.00018529791
STKc_Nek7cd082296.4e-05529791
PTKc_Syk_likecd050607.2e-07530791
STKc_MAP4K3_likecd066131.2e-06530789
STKc_Nek6_Nek7cd082246.8e-06531791
PTKc_Aatykcd050429.7e-06532788
STKc_PDK1cd055813.2e-06532785
STKc_OSR1_SPAKcd066102.8e-05532785
PTKc_Tie1cd050890.0001533812
PTKc_Tyk2_rpt2cd050803.5e-06533791
STKc_MAPKKKcd066063.1e-11533782
STKc_Cdc7_likecd066273e-07533779
STKc_CCRKcd078325.9e-06533780
STKc_MAPKcd078340.00035533822
STKc_CDK7cd078411.2e-08533783
STKc_Nekcd082158.4e-10533786
STKc_Nek2cd082170.00078533786
STKc_CNK2-likecd085300.00041533788
PTKc_Src_likecd050341.8e-10534789
STKc_CMGCcd051183.2e-07534785
STKc_AGCcd051237.9e-07534785
STKc_CDK_likecd078293.9e-06534779
STKc_CDK9_likecd078409.3e-05534779
PTKc_Trkcd050490.00024535791
STKc_MST3_likecd066090.00089535809
PKc_MEKcd066154.3e-05535805
STKc_MEKK4cd066261.6e-05535780
PTKc_c-roscd050441.2e-05536788
PTKccd001921.3e-12540787
PTKc_Fes_likecd050411.4e-11540788
PTKc_Srm_Brkcd051488.1e-08541789
STKc_SLK_likecd066110.00044541804
STKc_MAST_likecd055793.1e-07544783
PKc_MAPKKcd066057e-08545791
PKc_MAPKK_Byr1_likecd066202.5e-05545791
PKc_MAPKK_Pek1_likecd066210.00037545789
PTK_Rykcd050437.8e-05553793
CHDcd073027.1e-758591036
Nucleotidyl_cyc_IIIcd075561.7e-448591000
ANF_receptorpfam010943.3e-7144400
Pkinasepfam000691e-15534786
CyaACOG21141.1e-378091046
Guanylate_cycpfam002112.3e-1048521037
TyrKcsmart002199.5e-15513786
STYKcsmart002215.4e-11513786
Pkinase_Tyrpfam077145.2e-16517786
S_TKcsmart002206.6e-20523786
KINDsmart007500.00073602796
CYCcsmart000441.6e-1118251017

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_022588Diseasep.ALA409THRAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022592Diseasep.ARG957CYSAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022591Diseasep.ARG776TRPAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022585Diseasep.ASP176GLUAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_011968Polymorphismp.GLN771GLUN/A
Swiss-ProtVAR_022593Diseasep.GLY959ALAAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022589Diseasep.GLY413GLUAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_042219Polymorphismp.MET232ILEN/A
Swiss-ProtVAR_022583Diseasep.PRO32THRAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022586Diseasep.THR297METAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022584Diseasep.TRP115GLYAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022587Diseasep.TYR338CYSAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_022590Diseasep.TYR708CYSAcromesomelic dysplasia, Maroteaux type (AMDM)
Swiss-ProtVAR_042220Polymorphismp.VAL882ILEN/A
OMIM108961.0004 Diseasep.ARG388TERACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE
OMIM108961.0003 Diseasep.ASP176GLUACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE
OMIM108961.0001 Diseasep.PRO32THRACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE
OMIM108961.0002 Diseasep.TRP115GLYACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258