Results for the protein: Q8N5V2

Results for the Protein: Q8N5V2

114152090

25791

NGEF

NCBI, UniProt

NGEF_HUMAN RecName: Full=Ephexin-1; AltName: Full=Eph-interacting exchange protein; AltName: Full=Neuronal guanine nucleotide exchange factor

			0 3 0 2 1

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 PH_ephexin - cd01221 PH - smart00233 PH - pfam00169 PH-like - cd00900 PH - cd00821 SH3 - smart00326 SH3 - cd00174 SH3_2 - pfam07653 SH3_1 - pfam00018	Swiss-Prot Protein: Q8N5V2 Identical to: NP_062824 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PH_ephexin	cd01221	1.5e-72	488	603
PH	cd00821	5.1e-10	492	599
PH-like	cd00900	6e-09	492	599
SH3	cd00174	1.9e-14	616	670
RhoGEF	pfam00621	2.4e-50	278	456
PH	pfam00169	0.00034	490	601
SH3_1	pfam00018	1.8e-10	618	665
RhoGEF	smart00325	3.5e-45	277	456
PH	smart00233	5.7e-05	490	601
SH3	smart00326	8.1e-16	613	671
SH3_2	pfam07653	2.5e-05	616	670

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_027289	Polymorphism	p.ARG78GLY	N/A
dbSNP	rs4973588	Polymorphism	p.MET111THR	N/A
dbSNP	rs61729908	Polymorphism	p.VAL539GLY	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258