Results for the protein: P27037

Results for the Protein: P27037

114722

92

ACVR2A

NCBI, UniProt

AVR2A_HUMAN RecName: Full=Activin receptor type-2A; AltName: Full=Activin receptor type IIA; Short=ACTR-IIA; Short=ACTRIIA; Flags: Precursor

			0 3 0 0 3

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Swiss-Prot Protein: P27037

Identical to: NP_001607

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_MAP4K4_6	cd06636	0.00012	165	459
STKc_CDK9	cd07865	0.00038	179	472
PTKc_FGFR	cd05053	8.2e-05	180	433
STKc_TAO2	cd06634	0.00061	181	492
STKc_myosinIIIB	cd06639	5.3e-05	181	460
STKc_PAK	cd06614	8.5e-09	182	498
PTK_HER3	cd05111	2.8e-05	184	490
PTKc_ALK_LTK	cd05036	3.5e-05	185	481
PTKc_Tie2	cd05088	2.1e-05	185	474
STKc_myosinIIIA	cd06638	5.6e-05	185	459
STKc_MAP4K3	cd06645	7.1e-05	185	449
STKc_MAP4K5	cd06646	3.4e-05	185	453
PTKc_Csk_like	cd05039	6.8e-07	186	435
PTKc_Ror	cd05048	3.1e-05	186	425
PTKc_Trk	cd05049	6.1e-05	186	481
PTKc_Chk	cd05083	3.6e-05	186	465
PTKc_HER2	cd05109	0.00069	186	459
PTKc_InsR_like	cd05032	0.00051	187	481
PTKc_EphR	cd05033	1.7e-05	187	483
PTKc_Abl	cd05052	0.00016	187	452
PTKc_FAK	cd05056	0.0002	187	466
PTKc_EphR_B	cd05065	0.00012	187	483
PTKc_Frk_like	cd05068	3.2e-05	187	482
PTKc_Fyn_Yrk	cd05070	0.00061	187	465
PTKc_Lyn	cd05072	0.00013	187	452
PTKc_Hck	cd05073	0.00032	187	444
PTKc_Csk	cd05082	5.4e-05	187	461
PTKc_Jak1_rpt2	cd05079	0.00059	187	483
PTKc_DDR_like	cd05097	0.0006	187	481
PTKc_Btk_Bmx	cd05113	0.00016	187	480
PTKc_Lck_Blk	cd05067	0.00045	187	482
PKc_MKK4	cd06616	0.00066	187	459
STKc_ASK	cd06624	6.7e-06	187	463
STKc_MEKK3	cd06651	0.00087	187	454
STKc_CDK12	cd07864	3.6e-05	187	485
STKc_MAP4K3_like	cd06613	1.2e-09	188	450
PKc_MAPKK_Byr1_like	cd06620	0.00085	188	452
STKc_PCTAIRE_like	cd07844	0.00091	188	490
STKc_PCTAIRE2	cd07872	0.00055	188	501
PTKc_Jak_rpt2	cd05038	5.8e-07	189	483
PTKc_EGFR_like	cd05057	0.0002	189	489
PTKc_Jak2_Jak3_rpt2	cd05081	3.9e-07	189	483
PTKc_Tie1	cd05089	0.0008	189	480
PTKc_Itk	cd05112	1.8e-05	189	480
STKc_myosinIII_like	cd06608	1.7e-08	189	425
STKc_SLK_like	cd06611	2.7e-05	189	456
STKc_CDK10	cd07845	9.3e-05	189	474
STKc_MAPK15	cd07852	0.0009	189	489
STKc_Nek6_Nek7	cd08224	4.7e-05	189	484
STKc_Nek6	cd08228	0.00064	189	453
STKc_Nek7	cd08229	0.00018	189	453
PTKc_Src_like	cd05034	8.4e-06	190	444
PTKc_Src	cd05071	0.001	190	463
STKc_MST3_like	cd06609	2.9e-05	190	433
STKc_OSR1_SPAK	cd06610	3.4e-06	190	441
PKc_MEK	cd06615	0.001	190	498
PKc_MKK3_6	cd06617	2.5e-05	190	460
PKc_MAPKK_PBS2_like	cd06622	0.00048	190	509
STKc_STK25-YSK1	cd06642	0.00015	190	463
STKc_PAK_II	cd06648	0.00047	190	429
STKc_NAK1_like	cd06917	1.4e-06	190	503
STKc_CdkB_plant	cd07837	0.00037	190	491
STKc_CDKL1_4	cd07847	7.4e-05	190	481
STKc_ERK1_2_like	cd07849	0.00093	190	495
STKc_p38	cd07851	0.00022	190	484
SPS1	COG0515	5e-06	190	510
STKc_GRK4_like	cd05605	0.00048	191	513
STKc_MAPKKK	cd06606	2.5e-12	191	446
STKc_MEKK3_like	cd06625	3.4e-06	191	450
STKc_Cdc7_like	cd06627	8.3e-10	191	387
STKc_MAPK	cd07834	3.9e-05	191	482
STKc_Pho85	cd07836	0.00044	191	490
STKc_NLK	cd07853	6.6e-05	191	509
STKc_Nek3	cd08219	6.1e-05	191	454
PTKc_Axl_like	cd05035	0.00042	192	449
PTKc_Tyro3	cd05074	0.00041	192	452
PTKc_Tyk2_rpt2	cd05080	5.3e-06	192	484
PKc_MAPKK	cd06605	7.8e-07	192	450
STKc_TNIK	cd06637	1.6e-05	192	451
STKc_CDK_like	cd07829	3.8e-05	192	490
STKc_CDK1_like	cd07835	4.5e-05	192	481
STKc_CDK8_like	cd07842	0.00046	192	472
PTKc_Srm_Brk	cd05148	1.2e-06	193	448
STKc_Yank1	cd05578	1.8e-05	193	488
STKc_MST1_2	cd06612	3.9e-08	193	385
PKc_MAPKK_plant_like	cd06623	4.6e-07	193	493
STKc_MEKK4	cd06626	7.2e-08	193	412
STKc_YSK4	cd06631	3.4e-06	193	459
STKc_CCRK	cd07832	7.5e-08	193	486
STKc_CDK7	cd07841	1.6e-05	193	480
STKc_CDKL2_3	cd07846	0.0006	193	481
STKc_Nek	cd08215	1.1e-08	193	481
STKc_Nek2	cd08217	2.6e-05	193	450
STKc_Nek8	cd08220	3.8e-06	193	450
STKc_FA2-like	cd08529	0.00017	193	425
STKc_CNK2-like	cd08530	6.9e-05	193	454
PKc_STE	cd05122	2.4e-10	194	472
STKc_CDK9_like	cd07840	0.00024	195	465
PTKc	cd00192	1.7e-08	196	480
PTKc_Tie	cd05047	0.00021	196	463
PTKc_Musk	cd05050	2.3e-05	196	481
PTKc_Fes	cd05084	0.001	196	459
PTKc_Met_Ron	cd05058	0.00077	196	485
STKc_beta_ARK	cd05606	0.00055	197	477
STKc_PDK1	cd05581	1.6e-05	197	425
PKc	cd00180	5.3e-41	198	482
STKc_GRK1	cd05608	0.00027	199	503
PTKc_Ack_like	cd05040	2.8e-06	200	481
PTKc_Fes_like	cd05041	9.6e-06	200	434
STKc_AGC	cd05123	6.6e-05	200	485
STKc_MAPKKK_Bck1_lik	cd06629	0.00051	200	398
STKc_MEKK1_plant	cd06632	2e-06	200	416
STKc_CMGC	cd05118	9.3e-08	201	485
STKc_MEKK1	cd06630	0.00013	201	451
STKc_CDKL	cd07833	5.8e-05	201	485
STKc_GRK	cd05577	5.8e-05	267	453
Activin_recp	pfam01064	6.5e-08	28	118
Pkinase	pfam00069	1e-94	192	479
Pkinase_Tyr	pfam07714	5.6e-15	192	479
TyrKc	smart00219	3.3e-11	192	479
STYKc	smart00221	4.5e-21	192	463
S_TKc	smart00220	1.2e-20	202	489

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_064692	Polymorphism	p.ALA367THR	N/A
Swiss-Prot	VAR_032810	Polymorphism	p.ASP306ASN	N/A
Swiss-Prot	VAR_032809	Polymorphism	p.SER258ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258