Results for the protein: Q9Y2K2

Results for the Protein: Q9Y2K2

115502238

23387

SIK3

NCBI, UniProt

SIK3_HUMAN RecName: Full=Serine/threonine-protein kinase SIK3; AltName: Full=Salt-inducible kinase 3; Short=SIK-3; AltName: Full=Serine/threonine-protein kinase QSK

			0 4 0 0 4

Tips:

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Swiss-Prot Protein: Q9Y2K2

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTK_CCK4	cd05046	7.9e-05	1	263
PTKc_InsR	cd05061	1.2e-05	1	273
PTKc_Csk	cd05082	2.5e-07	1	261
PTKc_Tie2	cd05088	8.2e-06	1	275
PTKc_FGFR4	cd05099	3.2e-06	1	281
PTKc_FGFR3	cd05100	0.00041	1	296
PTKc_FGFR2	cd05101	5.1e-05	1	266
STKc_ROCK	cd05596	3.3e-06	1	323
STKc_ROCK2	cd05621	1.1e-07	1	318
STKc_ROCK1	cd05622	3.3e-07	1	319
STKc_myosinIII_like	cd06608	1.7e-11	1	259
STKc_TAO1	cd06635	2.1e-06	1	294
STKc_MAP4K4_6	cd06636	2e-06	1	259
STKc_TNIK	cd06637	1.3e-08	1	259
STKc_myosinIIIA	cd06638	2.4e-09	1	259
STKc_myosinIIIB	cd06639	4.9e-08	1	260
STKc_MAP4K3	cd06645	2.5e-08	1	258
STKc_PAK4	cd06657	3.5e-08	1	281
STKc_PAK6	cd06659	5.5e-09	1	285
STKc_TEY_MAPK_plant	cd07858	5e-13	1	302
STKc_CDK9	cd07865	2.1e-11	1	259
STKc_PFTAIRE2	cd07870	9.4e-07	1	303
STKc_JNK3	cd07874	1.1e-06	1	319
STKc_JNK1	cd07875	1.6e-05	1	301
STKc_p38beta_MAPK11	cd07878	5.3e-06	1	322
STKc_JNK2	cd07876	7.2e-07	1	297
PTKc_DDR	cd05051	9.8e-06	2	261
STKc_MAP4K3_like	cd06613	9e-14	2	258
STKc_PAK	cd06614	1.1e-21	2	272
STKc_TAO	cd06607	2.2e-07	2	298
STKc_TAO2	cd06634	3.2e-07	2	296
STKc_MST4	cd06640	4.4e-15	2	279
STKc_MST3	cd06641	5.9e-11	2	279
STKc_STK25-YSK1	cd06642	8.9e-13	2	279
STKc_STK10_LOK	cd06644	5.4e-09	2	279
PKc_MEK1	cd06650	0.00034	2	291
PKc_MEK2	cd06649	2.1e-05	2	344
STKc_PAK_II	cd06648	7.3e-14	2	272
PTKc_EphR	cd05033	7.6e-09	3	272
PTKc_ALK_LTK	cd05036	7.2e-06	3	259
PTKc_EGFR_like	cd05057	4.5e-07	3	273
PTKc_EphR_B	cd05065	1.3e-07	3	272
PTKc_EphR_A	cd05066	9.1e-07	3	272
PTK_Jak1_rpt1	cd05077	1.7e-05	3	258
PTKc_EGFR	cd05108	6.7e-07	3	308
PTKc_HER2	cd05109	1.5e-05	3	273
PTKc_HER4	cd05110	1.4e-05	3	297
PTK_HER3	cd05111	1.1e-07	3	273
PKc_MKK5	cd06619	2.3e-07	3	282
STKc_PAK_I	cd06647	3e-18	3	280
STKc_PAK1	cd06654	2.6e-10	3	282
STKc_PAK2	cd06655	2.8e-11	3	282
STKc_PAK3	cd06656	2.7e-10	3	283
STKc_PCTAIRE_like	cd07844	3.7e-13	3	303
STKc_CDK10	cd07845	3.9e-11	3	269
STKc_PFTAIRE1	cd07869	6.9e-05	3	273
STKc_PCTAIRE3	cd07871	1.3e-09	3	259
STKc_PCTAIRE2	cd07872	4.3e-08	3	279
STKc_CDK12	cd07864	1.9e-13	3	259
PTKc_EphR_A2	cd05063	8.4e-07	4	272
PTKc_Chk	cd05083	7.4e-06	4	260
PTKc_Ror	cd05048	3.6e-07	4	242
PTKc_TrkB	cd05093	1.5e-05	4	270
PTKc_TrkC	cd05094	0.00036	4	323
STKc_TAO3	cd06633	7e-05	4	294
STKc_PAK5	cd06658	3.1e-08	4	276
STKc_CDC2L1	cd07843	1.9e-11	4	259
STKc_ERK5	cd07855	1.9e-10	4	290
STKc_BUR1	cd07866	6.2e-13	4	259
PTKc_Csk_like	cd05039	1.8e-08	5	242
PTKc_FGFR1	cd05098	0.00013	5	266
PTKc_Itk	cd05112	8.4e-14	5	258
PTKc_Btk_Bmx	cd05113	1e-16	5	276
PTKc_Tec_Rlk	cd05114	1.4e-12	5	258
STKc_SLK_like	cd06611	1.2e-11	5	274
STKc_ASK	cd06624	2.7e-14	5	259
STKc_MAPK4_6	cd07854	1.6e-06	5	297
STKc_CDC2L6	cd07867	7.6e-05	5	311
STKc_CDK8	cd07868	0.00025	5	259
STKc_p38alpha_MAPK14	cd07877	9.7e-06	5	303
PK_STRAD	cd08216	3.3e-06	5	267
STKc_Nek6_Nek7	cd08224	9.3e-14	5	259
STKc_Nek6	cd08228	3.9e-09	5	261
STKc_Nek7	cd08229	8.7e-12	5	259
STKc_ROCK_NDR_like	cd05573	1.5e-14	6	312
STKc_DMPK_like	cd05597	3.5e-08	6	322
STKc_LATS	cd05598	1e-08	6	329
STKc_Sid2p_Dbf2p	cd05600	5.8e-10	6	331
STKc_MAST	cd05609	4.1e-24	6	319
STKc_PRKX_like	cd05612	7.3e-30	6	293
STKc_LATS2	cd05626	2.8e-05	6	329
STKc_NDR_like_fungal	cd05629	1e-06	6	332
STKc_MRCK_beta	cd05624	1.2e-07	6	319
STKc_NDR2	cd05627	1.5e-06	6	343
STKc_LATS1	cd05625	2e-06	6	329
STKc_MST3_like	cd06609	3.9e-17	6	279
PKc_MEK	cd06615	6.3e-09	6	278
PKc_MKK7	cd06618	1.6e-11	6	281
PKc_MAPKK_Pek1_like	cd06621	6.3e-11	6	276
PKc_MAPKK_plant_like	cd06623	5.3e-19	6	264
STKc_OSR1_SPAK	cd06610	2.1e-16	6	259
STKc_SLK	cd06643	1.1e-10	6	277
STKc_MEKK2	cd06652	8.9e-09	6	260
STKc_NAK1_like	cd06917	6.5e-16	6	276
STKc_CdkB_plant	cd07837	2.5e-13	6	260
STKc_CDKL	cd07833	8.5e-14	6	259
STKc_CDKL2_3	cd07846	5.8e-11	6	259
STKc_CDKL1_4	cd07847	9.2e-22	6	292
STKc_CDKL5	cd07848	8.3e-07	6	259
STKc_JNK	cd07850	1.2e-07	6	303
STKc_CDK1_euk	cd07861	3.9e-22	6	259
STKc_CDK6	cd07862	0.00024	6	283
STKc_PCTAIRE1	cd07873	3e-07	6	270
STKc_Nek1	cd08218	2.6e-25	6	259
SPS1	COG0515	5.4e-67	6	425
PTKc_RET	cd05045	3.4e-07	7	264
PTKc_Jak1_rpt2	cd05079	5.9e-05	7	261
PTKc_Tyk2_rpt2	cd05080	1.1e-05	7	280
PKc_STE	cd05122	2.4e-33	7	258
STKc_Yank1	cd05578	5.6e-28	7	259
STKc_MSK_N	cd05583	1.3e-22	7	278
STKc_GRK4_like	cd05605	4.3e-10	7	291
STKc_MSK1_N	cd05613	2.5e-12	7	277
STKc_cPKC_alpha	cd05615	6.3e-12	7	307
STKc_GRK6	cd05630	1.9e-07	7	286
STKc_GRK4	cd05631	3.1e-07	7	286
STKc_GRK5	cd05632	3.8e-08	7	286
STKc_MSK2_N	cd05614	3.5e-18	7	322
STKc_Cdc7_like	cd06627	3.4e-20	7	259
STKc_MAPKKK_Byr2_lik	cd06628	2.8e-20	7	259
STKc_YSK4	cd06631	5e-11	7	259
STKc_MEKK3	cd06651	8e-12	7	261
STKc_MEKK3_like_1	cd06653	1.5e-10	7	259
STKc_CCRK	cd07832	6.1e-15	7	260
STKc_CDK1_like	cd07835	1.6e-17	7	259
STKc_MAPK	cd07834	2.6e-14	7	316
STKc_Pho85	cd07836	2.2e-17	7	311
STKc_CDK5	cd07839	2.7e-10	7	259
STKc_CDK8_like	cd07842	9.3e-10	7	259
STKc_p38	cd07851	2.8e-09	7	286
STKc_NLK	cd07853	2.8e-11	7	351
STKc_Sty1_Hog1	cd07856	2.2e-09	7	289
STKc_MAPK15	cd07852	2.2e-13	7	317
STKc_TDY_MAPK_plant	cd07859	1.9e-09	7	302
STKc_CDK4	cd07863	2.5e-07	7	259
STKc_CDK2_3	cd07860	8.1e-16	7	259
STKc_p38gamma_MAPK12	cd07880	1.6e-06	7	341
STKc_MPK1	cd07857	9.3e-09	7	291
STKc_CDK7	cd07841	1.6e-15	7	279
STKc_Nek	cd08215	1.7e-57	7	259
STKc_Nek2	cd08217	1.5e-20	7	259
STKc_Nek3	cd08219	3.5e-26	7	259
STKc_Nek8	cd08220	1.7e-35	7	259
STKc_Nek9	cd08221	6.3e-14	7	259
STKc_Nek4	cd08223	2.6e-20	7	259
STKc_Nek5	cd08225	1.4e-26	7	259
STKc_Nek11	cd08222	5.1e-24	7	259
STKc_Nek10	cd08528	8.6e-09	7	256
STKc_CNK2-like	cd08530	2.4e-15	7	259
PTKc_Src_like	cd05034	1.6e-11	8	253
PTKc_Axl_like	cd05035	1.6e-05	8	261
PTKc_Abl	cd05052	5.6e-09	8	261
PTKc_FAK	cd05056	5.7e-10	8	266
PTKc_IGF-1R	cd05062	4.1e-05	8	258
PTKc_Lck_Blk	cd05067	2e-08	8	278
PTKc_Frk_like	cd05068	5.8e-17	8	264
PTKc_Yes	cd05069	3.8e-09	8	264
PTKc_Fyn_Yrk	cd05070	1e-07	8	258
PTKc_Src	cd05071	5.8e-08	8	260
PTKc_Hck	cd05073	8.4e-09	8	264
PTKc_Tyro3	cd05074	3e-06	8	261
PTKc_Axl	cd05075	0.001	8	261
PTKc_Lyn	cd05072	6.4e-09	8	278
PTKc_Tie1	cd05089	1.8e-06	8	282
STKc_CMGC	cd05118	3.2e-18	8	259
PTKc_Srm_Brk	cd05148	5.1e-11	8	251
STKc_PKA	cd05580	6.2e-21	8	271
STKc_PDK1	cd05581	3.8e-42	8	259
STKc_cPKC	cd05587	3.3e-29	8	321
STKc_PKN	cd05589	6.8e-18	8	320
STKc_CRIK	cd05601	1.1e-12	8	291
STKc_cPKC_beta	cd05616	5.9e-13	8	321
STKc_MRCK_alpha	cd05623	4.8e-09	8	318
STKc_NDR1	cd05628	2.8e-07	8	325
STKc_MST1_2	cd06612	7.7e-18	8	259
PKc_MKK4	cd06616	3.7e-09	8	279
PKc_MAPKK_PBS2_like	cd06622	7e-11	8	304
STKc_MAP4K5	cd06646	9e-08	8	258
STKc_CDK_like	cd07829	9.9e-22	8	259
STKc_MAK_like	cd07830	3.7e-14	8	259
STKc_MOK	cd07831	1.6e-11	8	259
STKc_CDK4_6_like	cd07838	1.6e-12	8	259
STKc_CDK9_like	cd07840	1.3e-19	8	259
STKc_ERK1_2_like	cd07849	4.4e-09	8	299
STKc_FA2-like	cd08529	3.1e-17	8	253
PTKc_InsR_like	cd05032	2.4e-08	9	259
PTKc_Musk	cd05050	5.8e-07	9	256
PTKc_FGFR	cd05053	7.8e-07	9	261
PTKc_EphR_A10	cd05064	1e-06	9	261
PTKc_Trk	cd05049	1.2e-06	9	257
PTKc_TrkA	cd05092	2e-05	9	264
PTKc_DDR2	cd05095	0.00079	9	277
PTKc_Ror2	cd05091	0.00023	9	251
STKc_MAPKKK	cd06606	5.2e-33	9	259
PKc_MKK3_6	cd06617	3.4e-11	9	274
PKc_MAPKK_Byr1_like	cd06620	3.7e-09	9	273
PK_STRAD_beta	cd08226	0.00025	9	315
PK_STRAD_alpha	cd08227	0.00021	9	345
PTKc_Tec_like	cd05059	2.6e-11	10	254
STKc_p70S6K	cd05584	2.8e-22	11	322
STKc_MEKK4	cd06626	6.3e-15	11	259
PTKc	cd00192	5.2e-14	12	258
PTK_Jak_rpt1	cd05037	0.00074	12	258
PTKc_Ack_like	cd05040	3.6e-12	12	255
PTKc_Fes_like	cd05041	3.4e-13	12	259
PTKc_Aatyk	cd05042	2.4e-06	12	261
PTKc_c-ros	cd05044	2.4e-05	12	260
PTKc_Tie	cd05047	1.7e-06	12	262
PTKc_Met_Ron	cd05058	2e-05	12	263
PTKc_Syk_like	cd05060	3.6e-10	12	255
PTK_Jak2_Jak3_rpt1	cd05078	1.3e-05	12	258
PTKc_Jak2_Jak3_rpt2	cd05081	2.6e-07	12	279
PTKc_Fer	cd05085	1.7e-09	12	259
PTKc_Aatyk1_Aatyk3	cd05087	0.00089	12	261
PTKc_Fes	cd05084	1.9e-09	12	259
PTKc_Syk	cd05116	1.2e-08	12	259
STKc_PKC	cd05570	1.5e-18	12	298
STKc_PKB	cd05571	1.9e-37	12	341
STKc_phototropin_lik	cd05574	2.3e-14	12	273
STKc_SGK	cd05575	4.4e-13	12	320
STKc_RSK_N	cd05582	8e-20	12	320
STKc_aPKC	cd05588	3.8e-29	12	321
STKc_nPKC_eta	cd05590	9.8e-30	12	321
STKc_nPKC_epsilon	cd05591	1.2e-24	12	321
STKc_nPKC_theta_delt	cd05592	1.4e-31	12	322
STKc_PKB_gamma	cd05593	3.8e-20	12	344
STKc_PKB_beta	cd05595	4.2e-30	12	341
STKc_NDR_like	cd05599	1.4e-06	12	303
STKc_SGK1	cd05602	9.4e-12	12	341
STKc_SGK2	cd05603	1.3e-20	12	321
STKc_PKB_alpha	cd05594	1.7e-23	12	340
STKc_SGK3	cd05604	2.4e-09	12	343
STKc_aPKC_zeta	cd05617	2.4e-16	12	321
STKc_aPKC_iota	cd05618	7.2e-14	12	307
STKc_nPKC_theta	cd05619	2.1e-16	12	322
STKc_nPKC_delta	cd05620	2e-09	12	322
PKc_MAPKK	cd06605	3.6e-12	12	264
STKc_MEKK3_like	cd06625	5.2e-15	12	259
STKc_MEKK1	cd06630	3.2e-10	12	260
STKc_MEKK1_plant	cd06632	6.3e-12	12	259
PTKc_Zap-70	cd05115	1.3e-08	13	262
STKc_beta_ARK	cd05606	3.2e-09	13	290
STKc_GRK3	cd05633	1.2e-07	13	282
PKc	cd00180	1.8e-87	14	257
STKc_AGC	cd05123	3.8e-47	14	259
STKc_cGK_PKG	cd05572	5.3e-26	14	265
STKc_GRK	cd05577	1.8e-11	14	269
STKc_YPK1_like	cd05585	1.2e-22	14	330
STKc_Sck1_like	cd05586	9.2e-26	14	363
STKc_MAST_like	cd05579	3.1e-22	14	264
STKc_GRK7	cd05607	5.2e-09	14	283
STKc_GRK1	cd05608	1.2e-11	14	290
STKc_Rim15_like	cd05611	2.3e-08	14	265
STKc_MAPKKK_Bck1_lik	cd06629	1.4e-10	14	259
Pkinase	pfam00069	7.2e-100	8	259
Pkinase_Tyr	pfam07714	4e-20	8	257
TyrKc	smart00219	3.7e-17	8	257
STYKc	smart00221	5.1e-94	8	259
S_TKc	smart00220	2.2e-103	18	259

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_035635	Polymorphism	p.ALA1103VAL	N/A
Swiss-Prot	VAR_051662	Polymorphism	p.ASP1040GLU	N/A
Swiss-Prot	VAR_035634	Polymorphism	p.HIS331LEU	N/A
Swiss-Prot	VAR_051663	Polymorphism	p.PRO1078ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258