Results for the protein: O15393

Results for the Protein: O15393

115502469

7113

TMPRSS2

NCBI, UniProt

TMPS2_HUMAN RecName: Full=Transmembrane protease serine 2; AltName: Full=Serine protease 10; Contains: RecName: Full=Transmembrane protease serine 2 non-catalytic chain; Contains: RecName: Full=Transmembrane protease serine 2 catalytic chain; Flags: Precursor

			0 5 0 1 4

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: LDLa - smart00192 LDLa - cd00112 SR - smart00202 Tryp_SPc - smart00020 Trypsin - pfam00089 Tryp_SPc - cd00190	Swiss-Prot Protein: O15393 Identical to: NP_005647 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Tryp_SPc	cd00190	5e-106	256	487
Trypsin	pfam00089	3.7e-77	256	484
LDLa	smart00192	3.7e-07	112	145
SR	smart00202	1.2e-07	149	242
Tryp_SPc	smart00020	1.1e-103	255	484

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_038004	Polymorphism	p.ASP491ASN	N/A
Swiss-Prot	VAR_038003	Polymorphism	p.GLU329GLN	N/A
Swiss-Prot	VAR_011692	Polymorphism	p.LYS449ASN	N/A
Swiss-Prot	VAR_038002	Polymorphism	p.SER254CYS	N/A
dbSNP	rs12329760	Polymorphism	p.VAL160MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258