Results for the protein: P01730

Results for the Protein: P01730

116013

920

CD4

NCBI, UniProt

CD4_HUMAN RecName: Full=T-cell surface glycoprotein CD4; AltName: Full=T-cell surface antigen T4/Leu-3; AltName: CD_antigen=CD4; Flags: Precursor

Known Diseases associated with this Protein:
OKT4 EPITOPE DEFICIENCY

1

3

1

2

1

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: IG_like - smart00410 IG - smart00409 V-set - pfam07686 Ig1_CD4 - cd07690 IgV - cd00099 Ig_CEACAM_D1_like - cd05741 ig - pfam00047 IGv - smart00406 Ig - cd00096 Ig2_CD4 - cd07694 C2-set - pfam05790 CD4-extracel - pfam09191 Ig3_CD4_like - cd07695 Tcell_CD4_Cterm - pfam12104	Swiss-Prot Protein: P01730 Identical to: NP_000607 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
IgV	cd00099	0.00065	29	122
Ig_CEACAM_D1_like	cd05741	0.00071	34	122
Ig	cd00096	4.8e-07	37	128
Ig2_CD4	cd07694	4.1e-51	123	204
Ig3_CD4_like	cd07695	1.9e-64	209	314
ig	pfam00047	2.4e-11	34	111
IG	smart00409	9.3e-14	26	123
IG_like	smart00410	9.3e-14	26	123
V-set	pfam07686	0.00051	28	122
IGv	smart00406	1e-13	36	111
C2-set	pfam05790	3.1e-26	125	203
CD4-extracel	pfam09191	1e-69	207	316
C2-set	pfam05790	3.3e-24	317	390
Tcell_CD4_Cterm	pfam12104	1.4e-17	426	453

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs28919570	Polymorphism	p.ARG265TRP	N/A
Swiss-Prot	VAR_023459	Polymorphism	p.LYS191GLU	N/A
dbSNP	rs11064419	Polymorphism	p.PHE227SER	N/A
OMIM	186940.0001	Disease	p.ARG240TRP	OKT4 EPITOPE DEFICIENCY

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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