Results for the protein: P24941

Results for the Protein: P24941

116051

1017

CDK2

NCBI, UniProt

CDK2_HUMAN RecName: Full=Cyclin-dependent kinase 2; AltName: Full=Cell division protein kinase 2; AltName: Full=p33 protein kinase

			0 4 0 0 4

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P24941

Identical to: NP_001789

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_EphR	cd05033	4.9e-07	1	267
PTKc_Jak_rpt2	cd05038	8.1e-12	1	252
PTKc_Csk_like	cd05039	8.1e-07	1	215
PTKc_Ror	cd05048	1.3e-08	1	222
PTKc_Trk	cd05049	4.8e-08	1	242
PTKc_Abl	cd05052	3.4e-09	1	252
PTKc_EGFR_like	cd05057	2.9e-05	1	265
PTKc_InsR	cd05061	9e-06	1	268
PTKc_IGF-1R	cd05062	3.4e-05	1	257
PTKc_Lck_Blk	cd05067	4.6e-07	1	293
PTKc_Frk_like	cd05068	1.1e-14	1	248
PTKc_Yes	cd05069	2.1e-07	1	248
PTKc_Fyn_Yrk	cd05070	1.1e-06	1	248
PTKc_Src	cd05071	1.8e-06	1	249
PTKc_Lyn	cd05072	7.6e-08	1	248
PTKc_Hck	cd05073	7.9e-09	1	248
PTKc_Jak1_rpt2	cd05079	5.4e-10	1	290
PTKc_Csk	cd05082	6.5e-06	1	251
PTKc_Chk	cd05083	1.7e-09	1	258
PTKc_Tie2	cd05088	7.5e-06	1	279
PTKc_Tie1	cd05089	7.3e-05	1	273
PTKc_Ror1	cd05090	7.6e-07	1	258
PTKc_Ror2	cd05091	8.4e-06	1	258
PTKc_TrkA	cd05092	4.5e-06	1	265
PTKc_TrkB	cd05093	1.8e-05	1	256
PTKc_TrkC	cd05094	0.00016	1	288
PTKc_DDR2	cd05095	2.2e-06	1	264
PTKc_DDR1	cd05096	0.0001	1	265
PTKc_DDR_like	cd05097	2.4e-06	1	264
PTKc_FGFR1	cd05098	0.00032	1	267
PTKc_FGFR3	cd05100	0.00082	1	288
PTKc_FGFR2	cd05101	0.00026	1	270
PTK_HER3	cd05111	0.00027	1	278
PTKc_Btk_Bmx	cd05113	2.4e-08	1	252
PTKc_FGFR4	cd05099	3.7e-06	1	272
STKc_ROCK2	cd05621	0.00056	1	297
STKc_SLK_like	cd06611	3.3e-12	1	298
STKc_MAP4K3_like	cd06613	2.3e-16	1	285
PKc_MKK4	cd06616	4.5e-09	1	267
PKc_MKK7	cd06618	2.5e-09	1	292
STKc_ASK	cd06624	2.6e-16	1	286
STKc_TAO2	cd06634	2.4e-07	1	279
STKc_myosinIIIA	cd06638	1.2e-07	1	263
STKc_myosinIIIB	cd06639	9.5e-08	1	287
STKc_STK10_LOK	cd06644	2.1e-10	1	293
STKc_MAP4K3	cd06645	3.7e-09	1	285
STKc_MAP4K5	cd06646	1.3e-09	1	285
STKc_PAK_I	cd06647	9.6e-13	1	298
STKc_PAK1	cd06654	3.6e-09	1	297
STKc_PAK2	cd06655	4.6e-10	1	297
STKc_PAK3	cd06656	7e-10	1	297
STKc_PAK5	cd06658	1.7e-07	1	297
STKc_PCTAIRE_like	cd07844	2.6e-127	1	286
STKc_CDK10	cd07845	3.4e-106	1	294
STKc_MAPK15	cd07852	2.4e-53	1	298
STKc_TEY_MAPK_plant	cd07858	2.8e-59	1	298
STKc_JNK	cd07850	1.1e-34	1	298
STKc_CDK12	cd07864	5.4e-98	1	286
STKc_CDK9	cd07865	2.2e-81	1	286
STKc_BUR1	cd07866	3.1e-78	1	286
STKc_PFTAIRE1	cd07869	5.8e-101	1	298
STKc_PFTAIRE2	cd07870	1.2e-103	1	286
STKc_PCTAIRE3	cd07871	3.8e-123	1	286
STKc_PCTAIRE2	cd07872	4.2e-114	1	297
STKc_PCTAIRE1	cd07873	5.6e-122	1	298
STKc_JNK3	cd07874	3.4e-16	1	297
STKc_JNK2	cd07876	6.3e-18	1	297
STKc_p38gamma_MAPK12	cd07880	1.2e-41	1	298
STKc_Nek6_Nek7	cd08224	1.5e-31	1	284
STKc_Nek6	cd08228	7.6e-24	1	275
STKc_Nek7	cd08229	2.4e-21	1	277
PTKc_Src_like	cd05034	7.5e-10	2	248
PTK_Ryk	cd05043	4.6e-06	2	252
PTK_CCK4	cd05046	0.00013	2	250
PTKc_Musk	cd05050	4.9e-09	2	257
PTKc_FGFR	cd05053	5e-07	2	253
PTKc_FAK	cd05056	1.5e-08	2	263
PTKc_EphR_A2	cd05063	4.9e-05	2	256
PTKc_EphR_A10	cd05064	0.00062	2	267
PTKc_EphR_A	cd05066	0.00022	2	259
PTKc_EGFR	cd05108	7.8e-05	2	298
PTKc_HER2	cd05109	9.1e-05	2	265
PTKc_HER4	cd05110	0.00021	2	285
PTKc_Itk	cd05112	1.2e-08	2	248
PTKc_Tec_Rlk	cd05114	1.4e-06	2	256
PTKc_Srm_Brk	cd05148	1e-09	2	251
STKc_phototropin_lik	cd05574	2e-09	2	296
STKc_ROCK_NDR_like	cd05573	8.7e-10	2	287
STKc_PKA	cd05580	5.2e-11	2	298
STKc_PDK1	cd05581	1.3e-18	2	286
STKc_DMPK_like	cd05597	0.00018	2	291
STKc_LATS	cd05598	0.00046	2	294
STKc_NDR_like	cd05599	2.2e-06	2	258
STKc_Sid2p_Dbf2p	cd05600	6.1e-08	2	295
STKc_CRIK	cd05601	2.6e-07	2	289
STKc_MAST	cd05609	1.8e-07	2	298
STKc_MRCK_alpha	cd05623	0.00031	2	293
STKc_NDR1	cd05628	0.00059	2	294
STKc_MRCK_beta	cd05624	0.00084	2	298
STKc_PRKX_like	cd05612	5.4e-09	2	294
PTKc_ALK_LTK	cd05036	3.4e-07	2	257
PKc_MAPKK	cd06605	9.2e-16	2	291
STKc_TAO	cd06607	2.7e-08	2	278
STKc_myosinIII_like	cd06608	3.3e-11	2	286
STKc_MST3_like	cd06609	2e-15	2	297
STKc_OSR1_SPAK	cd06610	3.2e-15	2	286
STKc_MST1_2	cd06612	9e-19	2	286
STKc_PAK	cd06614	2.5e-20	2	296
PKc_MKK3_6	cd06617	1e-10	2	288
PKc_MKK5	cd06619	3.3e-07	2	297
PKc_MAPKK_Byr1_like	cd06620	4.3e-08	2	292
PKc_MAPKK_PBS2_like	cd06622	4.2e-09	2	297
PKc_MAPKK_Pek1_like	cd06621	1e-11	2	248
PKc_MAPKK_plant_like	cd06623	4.4e-19	2	291
STKc_MEKK3_like	cd06625	7.1e-15	2	286
STKc_TAO3	cd06633	4e-06	2	278
STKc_TAO1	cd06635	1.6e-06	2	295
STKc_MST4	cd06640	9.7e-08	2	289
STKc_MST3	cd06641	5.8e-08	2	276
STKc_STK25-YSK1	cd06642	8.1e-09	2	289
STKc_SLK	cd06643	1e-10	2	284
STKc_PAK_II	cd06648	7.2e-12	2	296
PKc_MEK2	cd06649	4.7e-07	2	296
PKc_MEK1	cd06650	3.6e-06	2	297
STKc_MEKK2	cd06652	1.6e-07	2	265
STKc_MEKK3_like_1	cd06653	1.3e-09	2	264
STKc_PAK4	cd06657	4e-07	2	297
STKc_PAK6	cd06659	1.1e-09	2	298
PKc_MEK	cd06615	7.1e-11	2	296
STKc_NAK1_like	cd06917	3.2e-14	2	294
STKc_CDKL	cd07833	8.6e-82	2	286
STKc_CdkB_plant	cd07837	3.4e-167	2	287
STKc_CDC2L1	cd07843	1.4e-128	2	286
STKc_CDKL2_3	cd07846	6.8e-73	2	286
STKc_CDKL1_4	cd07847	5.2e-82	2	286
STKc_CDKL5	cd07848	7.6e-51	2	286
STKc_ERK1_2_like	cd07849	3.8e-48	2	297
STKc_p38	cd07851	7.7e-45	2	292
STKc_ERK5	cd07855	7.3e-49	2	295
STKc_Sty1_Hog1	cd07856	2.7e-46	2	298
STKc_CDK6	cd07862	4.4e-97	2	286
STKc_JNK1	cd07875	1.1e-16	2	297
STKc_p38alpha_MAPK14	cd07877	1.7e-33	2	294
STKc_p38beta_MAPK11	cd07878	4.3e-35	2	298
STKc_p38delta_MAPK13	cd07879	1.1e-42	2	294
SPS1	COG0515	1.5e-54	2	297
PTKc_RET	cd05045	1e-05	3	255
PTKc_EphR_B	cd05065	2.3e-05	3	259
PKc_STE	cd05122	6.1e-39	3	285
STKc_Yank1	cd05578	4.3e-16	3	286
STKc_MSK_N	cd05583	7.5e-09	3	292
STKc_cPKC	cd05587	4.9e-06	3	290
STKc_GRK4_like	cd05605	1.3e-09	3	298
STKc_GRK6	cd05630	1.1e-06	3	294
STKc_GRK4	cd05631	2.5e-06	3	289
STKc_GRK5	cd05632	6e-07	3	289
STKc_MSK1_N	cd05613	2.4e-06	3	292
STKc_MSK2_N	cd05614	2.6e-05	3	294
STKc_cPKC_alpha	cd05615	3.8e-06	3	297
STKc_cPKC_beta	cd05616	6.2e-06	3	297
STKc_MAPKKK	cd06606	3.1e-48	3	286
STKc_Cdc7_like	cd06627	5.6e-28	3	286
STKc_MAPKKK_Bck1_lik	cd06629	9.2e-16	3	286
STKc_MEKK1	cd06630	2.1e-12	3	287
STKc_YSK4	cd06631	2.4e-12	3	286
STKc_MEKK1_plant	cd06632	1.7e-19	3	286
STKc_MEKK3	cd06651	1.7e-10	3	288
STKc_MAPKKK_Byr2_lik	cd06628	5.4e-27	3	286
STKc_MAPK	cd07834	8.3e-75	3	298
STKc_Pho85	cd07836	2.6e-147	3	286
STKc_CDK5	cd07839	1.3e-164	3	286
STKc_CDK7	cd07841	2.7e-134	3	297
STKc_CDK8_like	cd07842	1.3e-91	3	286
STKc_CCRK	cd07832	3.8e-124	3	287
STKc_NLK	cd07853	6.3e-21	3	298
STKc_MAPK4_6	cd07854	2.4e-23	3	297
STKc_MPK1	cd07857	9e-46	3	296
STKc_TDY_MAPK_plant	cd07859	6.9e-46	3	298
STKc_CDK2_3	cd07860	6.8e-226	3	286
STKc_CDK1_euk	cd07861	1.2e-175	3	286
STKc_CDK4	cd07863	2.5e-100	3	286
STKc_Nek2	cd08217	7.9e-18	3	286
STKc_Nek1	cd08218	3.9e-22	3	286
STKc_Nek3	cd08219	6.5e-17	3	286
STKc_Nek8	cd08220	1.4e-13	3	286
STKc_Nek9	cd08221	5.2e-11	3	286
STKc_Nek11	cd08222	6.7e-13	3	286
STKc_Nek4	cd08223	1.8e-10	3	286
STKc_Nek5	cd08225	2.4e-23	3	286
STKc_Nek	cd08215	4.6e-28	3	286
STKc_Nek10	cd08528	3.4e-08	3	257
STKc_FA2-like	cd08529	3e-14	3	286
STKc_CNK2-like	cd08530	2.2e-12	3	286
PTKc_Axl_like	cd05035	9.3e-07	4	252
PTKc_Axl	cd05075	3.3e-05	4	252
PTKc_Tyk2_rpt2	cd05080	4.9e-09	4	260
PTKc_Jak2_Jak3_rpt2	cd05081	8.2e-08	4	250
PTKc_Tyro3	cd05074	4.2e-06	4	252
STKc_CMGC	cd05118	2.3e-199	4	286
STKc_PKN	cd05589	3.9e-07	4	289
STKc_MAP4K4_6	cd06636	2.9e-05	4	286
STKc_TNIK	cd06637	3.2e-07	4	286
STKc_CDK_like	cd07829	4.6e-216	4	286
STKc_MAK_like	cd07830	2.1e-88	4	286
STKc_MOK	cd07831	6.5e-57	4	286
STKc_CDK1_like	cd07835	1.9e-176	4	286
STKc_CDK4_6_like	cd07838	6.9e-125	4	286
STKc_CDK9_like	cd07840	1.1e-128	4	286
STKc_CDC2L6	cd07867	2.2e-48	4	286
STKc_CDK8	cd07868	3.1e-48	4	286
STKc_MEKK4	cd06626	9.8e-19	5	286
PK_STRAD	cd08216	4.4e-06	5	292
PK_STRAD_alpha	cd08227	0.00025	5	298
STKc_PKC	cd05570	3.1e-11	6	298
STKc_nPKC_epsilon	cd05591	4.4e-07	6	297
STKc_SGK1	cd05602	0.00017	6	294
STKc_SGK3	cd05604	0.00029	6	294
STKc_nPKC_delta	cd05620	5.4e-05	6	294
PK_STRAD_beta	cd08226	0.00074	6	295
PTKc_Tec_like	cd05059	6.4e-09	7	248
PTKc_Zap-70	cd05115	3.4e-06	7	260
STKc_RSK_N	cd05582	1.4e-06	7	292
STKc_p70S6K	cd05584	1e-06	7	294
PTKc	cd00192	1.6e-12	8	285
PTKc_Ack_like	cd05040	2.3e-12	8	250
PTKc_Fes_like	cd05041	4.1e-11	8	257
PTKc_Aatyk	cd05042	0.00067	8	240
PTKc_c-ros	cd05044	1.3e-05	8	257
PTKc_Tie	cd05047	4.5e-05	8	253
PTKc_Met_Ron	cd05058	1.4e-06	8	261
PTKc_Syk_like	cd05060	1.3e-08	8	260
PTKc_Fes	cd05084	1.2e-08	8	257
PTKc_Fer	cd05085	2.7e-07	8	257
PTKc_Syk	cd05116	1.9e-06	8	260
STKc_PKB	cd05571	3.9e-07	8	294
STKc_SGK	cd05575	7.6e-06	8	292
STKc_aPKC	cd05588	5.8e-07	8	290
STKc_nPKC_eta	cd05590	7.6e-06	8	297
STKc_nPKC_theta_delt	cd05592	3.2e-07	8	294
STKc_PKB_alpha	cd05594	1.9e-06	8	295
STKc_PKB_beta	cd05595	1.5e-05	8	294
STKc_PKB_gamma	cd05593	1.5e-05	8	281
STKc_SGK2	cd05603	6.9e-07	8	290
STKc_aPKC_zeta	cd05617	1.9e-06	8	287
STKc_aPKC_iota	cd05618	1.2e-05	8	290
STKc_nPKC_theta	cd05619	5.5e-09	8	294
PKc	cd00180	3.9e-92	10	284
STKc_AGC	cd05123	3.7e-25	10	286
STKc_cGK_PKG	cd05572	3.6e-13	10	291
STKc_GRK	cd05577	5.5e-11	10	295
STKc_MAST_like	cd05579	1.8e-17	10	291
STKc_YPK1_like	cd05585	4.2e-07	10	298
STKc_Sck1_like	cd05586	0.0001	10	298
STKc_beta_ARK	cd05606	7.7e-07	10	288
STKc_GRK7	cd05607	1.2e-08	10	288
STKc_GRK1	cd05608	2.4e-09	10	288
STKc_Rim15_like	cd05611	3.3e-07	10	292
STKc_GRK3	cd05633	9.6e-06	10	293
Pkinase	pfam00069	3.2e-115	4	286
Pkinase_Tyr	pfam07714	1.8e-15	4	286
TyrKc	smart00219	2e-14	4	248
STYKc	smart00221	7.6e-107	4	286
S_TKc	smart00220	2.6e-119	14	286
KIND	smart00750	0.00051	93	296

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041972	Polymorphism	p.PRO45LEU	N/A
Swiss-Prot	VAR_019988	Polymorphism	p.THR290SER	N/A
Swiss-Prot	VAR_016157	Polymorphism	p.TYR15SER	N/A
Swiss-Prot	VAR_053927	Polymorphism	p.VAL18LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258