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Results for the Protein: Q07864
116241339

DPOE1_HUMAN RecName: Full=DNA polymerase epsilon catalytic subunit A; AltName: Full=DNA polymerase II subunit A

Known Diseases associated with this Protein:
  COLORECTAL CANCER 12 (CRCS12)
  COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
2
35
1
3
33
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

PolB - COG0417
DNA_pol_B_exo1 - pfam03104
DNA_polB_B1_exo - cd05783
POLBc - smart00486
DNA_polB_Kod1_like_e - cd05780
DNA_polB_epsilon_exo - cd05779
DNA_polB_like1_exo - cd05782
DEDDy_DNA_polB_exo - cd05160
POLBc_epsilon - cd05535
POLBc - cd00145
POLBc_B3 - cd05536
DUF1744 - pfam08490


Swiss-Prot Protein: Q07864
Identical to: NP_006222
   Default View:










Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PolBCOG04171.5e-233771188
DNA_polB_B1_exocd057830.00015265473
DNA_polB_Kod1_like_ecd057801.1e-08267473
DNA_polB_epsilon_exocd057798.6e-180268471
DEDDy_DNA_polB_exocd051603.4e-73271471
DNA_polB_like1_exocd057820.0002271472
POLBc_epsiloncd055355311153
POLBccd001452.6e-1106041147
POLBc_B3cd055364.8e-077631115
DNA_pol_B_exo1pfam031043.1e-13486427
POLBcsmart004864.2e-143267870
DUF1744pfam084901.7e-24915251925

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_061138Polymorphismp.ALA31SERN/A
Swiss-ProtVAR_069339Polymorphismp.ALA189THRN/A
Swiss-ProtVAR_069355Polymorphismp.ALA2056THRN/A
Swiss-ProtVAR_028433Polymorphismp.ALA1712VALN/A
Swiss-ProtVAR_020282Polymorphismp.ALA2040VALN/A
Swiss-ProtVAR_069356Polymorphismp.ALA2213VALN/A
dbSNPrs5744751 Polymorphismp.ALA252VALN/A
Swiss-ProtVAR_028431Polymorphismp.ARG1382CYSN/A
Swiss-ProtVAR_048882Polymorphismp.ARG2159CYSN/A
Swiss-ProtVAR_028430Polymorphismp.ARG260GLNN/A
Swiss-ProtVAR_020283Polymorphismp.ARG2165HISN/A
Swiss-ProtVAR_069340Polymorphismp.ARG231HISN/A
Swiss-ProtVAR_069347Polymorphismp.ARG762TRPN/A
Swiss-ProtVAR_020280Polymorphismp.ASN1396SERN/A
dbSNPrs5744760 Polymorphismp.ASN336SERN/A
Swiss-ProtVAR_069353Polymorphismp.ASP1752ASNN/A
Swiss-ProtVAR_069354Polymorphismp.ASP2013ASNN/A
Swiss-ProtVAR_028435Polymorphismp.CYS1935TYRN/A
Swiss-ProtVAR_028432Polymorphismp.GLU1577ALAN/A
Swiss-ProtVAR_020281Polymorphismp.GLU1399GLNN/A
dbSNPrs5745066 Polymorphismp.GLU2140LYSN/A
Swiss-ProtVAR_069350Polymorphismp.LEU1255VALN/A
Swiss-ProtVAR_069344Diseasep.LEU424VALColorectal cancer 12 (CRCS12)
Swiss-ProtVAR_028434Polymorphismp.LYS1857ARGN/A
Swiss-ProtVAR_069349Polymorphismp.LYS1008ASNN/A
Swiss-ProtVAR_069348Polymorphismp.LYS777ASNN/A
Swiss-ProtVAR_020278Polymorphismp.PHE695ILEN/A
Swiss-ProtVAR_069342Polymorphismp.PHE367SERN/A
Swiss-ProtVAR_069345Polymorphismp.PRO436ARGN/A
Swiss-ProtVAR_069341Polymorphismp.PRO286HISN/A
Swiss-ProtVAR_028429Polymorphismp.PRO99LEUN/A
Swiss-ProtVAR_069352Polymorphismp.PRO1421SERN/A
Swiss-ProtVAR_069346Polymorphismp.SER459PHEN/A
Swiss-ProtVAR_020279Polymorphismp.TYR1395CYSN/A
Swiss-ProtVAR_069343Polymorphismp.VAL411LEUN/A
Swiss-ProtVAR_069351Polymorphismp.VAL1368METN/A
OMIM174762.0001 Diseasep.LEU424VALCOLORECTAL CANCER, SUSCEPTIBILITY TO, 12



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