Results for the protein: Q13470

Results for the Protein: Q13470

116242821

8711

TNK1

NCBI, UniProt

TNK1_HUMAN RecName: Full=Non-receptor tyrosine-protein kinase TNK1; AltName: Full=CD38 negative kinase 1

			0 6 0 0 6

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Swiss-Prot Protein: Q13470

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_Kit	cd05104	8.7e-09	20	381
PTKc_PDGFR_beta	cd05107	3.2e-06	20	382
PTKc_VEGFR	cd05054	8.2e-07	37	380
PTKc_CSF-1R	cd05106	9.2e-06	74	382
PTKc_PDGFR	cd05055	3.6e-11	77	381
PTKc_FGFR1	cd05098	6.8e-13	96	384
PTK_Tyk2_rpt1	cd05076	2e-05	98	378
STKc_PAK5	cd06658	0.00014	98	395
PTKc_FGFR2	cd05101	1.3e-13	99	384
PTKc_FGFR4	cd05099	4e-20	100	405
PTKc_FGFR3	cd05100	5.2e-10	100	424
STKc_PAK_I	cd06647	0.00012	101	398
STKc_PAK_II	cd06648	1.2e-07	102	390
STKc_PAK1	cd06654	7.9e-05	102	400
STKc_PAK2	cd06655	9.1e-05	102	401
STKc_PAK3	cd06656	6.2e-05	102	402
STKc_myosinIIIA	cd06638	0.00028	103	382
STKc_STK10_LOK	cd06644	3.4e-05	104	408
STKc_PAK4	cd06657	0.00033	104	398
STKc_PAK6	cd06659	1.9e-05	104	404
PKc_MKK7	cd06618	0.0002	105	401
STKc_PAK	cd06614	7e-10	106	391
STKc_MAP4K5	cd06646	0.00038	106	378
STKc_MAP4K3	cd06645	0.00026	106	381
PTKc_EGFR	cd05108	4.5e-43	107	430
PTKc_HER4	cd05110	1.2e-36	107	418
STKc_ASK	cd06624	3.1e-05	107	377
PTKc_EGFR_like	cd05057	1.1e-55	108	389
PTKc_VEGFR3	cd05102	1.5e-11	108	380
PTKc_VEGFR2	cd05103	7e-10	108	380
PTKc_HER2	cd05109	1.1e-38	108	389
PTK_HER3	cd05111	1.2e-39	108	389
PTKc_ALK_LTK	cd05036	1e-22	109	379
PTKc_FAK	cd05056	6.2e-71	109	385
PTKc_Chk	cd05083	4.4e-38	109	380
PTKc_Tie2	cd05088	8.3e-12	109	398
PTKc_TrkA	cd05092	1.4e-22	109	379
PTKc_Csk_like	cd05039	8.8e-21	110	380
PTKc_Ror	cd05048	1.3e-21	110	376
PTKc_Trk	cd05049	1.2e-21	110	379
PTKc_DDR	cd05051	3.4e-21	110	379
STKc_SLK	cd06643	3.9e-05	110	396
STKc_PFTAIRE2	cd07870	0.00023	110	410
PTKc_InsR_like	cd05032	4.3e-30	111	379
PTKc_Src_like	cd05034	2.5e-35	111	380
PTKc_EphR	cd05033	7.9e-46	111	381
PTKc_Jak_rpt2	cd05038	8.9e-51	111	380
PTKc_Musk	cd05050	4.4e-27	111	379
PTKc_Abl	cd05052	3.6e-43	111	381
PTKc_FGFR	cd05053	1.1e-14	111	378
PTKc_Tec_like	cd05059	2.7e-32	111	378
PTKc_InsR	cd05061	2.2e-30	111	393
PTKc_IGF-1R	cd05062	1.1e-29	111	379
PTKc_EphR_A2	cd05063	2.8e-40	111	381
PTKc_EphR_A10	cd05064	1e-39	111	381
PTKc_EphR_B	cd05065	8.9e-41	111	381
PTKc_EphR_A	cd05066	2.7e-48	111	381
PTKc_Frk_like	cd05068	5.2e-52	111	380
PTKc_Yes	cd05069	4.4e-24	111	380
PTKc_Src	cd05071	4e-30	111	382
PTKc_Lyn	cd05072	1.9e-27	111	380
PTKc_Hck	cd05073	2.4e-34	111	380
PTKc_Lck_Blk	cd05067	7e-36	111	380
PTKc_Fyn_Yrk	cd05070	2.3e-28	111	380
PTKc_Jak1_rpt2	cd05079	8.4e-28	111	377
PTKc_Ror1	cd05090	1.3e-26	111	380
PTKc_Ror2	cd05091	2.6e-26	111	380
PTKc_TrkB	cd05093	1.1e-22	111	389
PTKc_TrkC	cd05094	9.5e-12	111	389
PTKc_DDR2	cd05095	1.8e-26	111	379
PTKc_DDR1	cd05096	7e-24	111	379
PTKc_DDR_like	cd05097	6e-33	111	379
PTKc_Btk_Bmx	cd05113	3.6e-39	111	378
PTKc_Tec_Rlk	cd05114	1e-42	111	378
PTKc_Itk	cd05112	5.4e-45	111	378
STKc_Nek6_Nek7	cd08224	2.8e-06	111	385
PTK_Ryk	cd05043	5.8e-20	112	379
STKc_MST1_2	cd06612	2e-08	112	370
STKc_MAP4K3_like	cd06613	1.5e-08	112	381
STKc_myosinIII_like	cd06608	6.5e-07	112	377
STKc_TNIK	cd06637	0.0006	112	377
STKc_MST4	cd06640	2.8e-05	112	403
STKc_MST3	cd06641	2.2e-05	112	400
STKc_STK25-YSK1	cd06642	3.1e-06	112	398
STKc_MEKK3_like_1	cd06653	0.0001	112	381
STKc_PCTAIRE_like	cd07844	9.5e-05	112	410
PKc_MAPKK	cd06605	0.00021	113	382
STKc_MEKK2	cd06652	5e-05	113	372
STKc_CDK12	cd07864	0.00023	113	397
STKc_Nek3	cd08219	6.9e-06	113	377
STKc_Nek10	cd08528	3.1e-05	113	379
PTKc_Tie1	cd05089	1.3e-11	114	397
STKc_PRKX_like	cd05612	0.00065	114	403
STKc_MST3_like	cd06609	1.1e-10	114	398
PKc_MAPKK_plant_like	cd06623	7.8e-09	114	382
STKc_CdkB_plant	cd07837	2.2e-05	114	371
STKc_PCTAIRE3	cd07871	0.00019	114	396
STKc_PCTAIRE2	cd07872	0.00031	114	418
STKc_Nek6	cd08228	5.7e-05	114	382
SPS1	COG0515	6.8e-19	114	567
PTKc_RET	cd05045	7.9e-29	115	380
PTK_CCK4	cd05046	5.4e-18	115	379
PTKc_Csk	cd05082	4.2e-25	115	380
PKc_STE	cd05122	3e-11	115	373
STKc_MAPKKK	cd06606	7.7e-17	115	371
STKc_MAPKKK_Byr2_lik	cd06628	9.2e-10	115	377
STKc_MAPKKK_Bck1_lik	cd06629	2.5e-07	115	371
STKc_MEKK3	cd06651	1.4e-08	115	384
STKc_Pho85	cd07836	0.00018	115	397
STKc_CDK10	cd07845	2.9e-07	115	371
STKc_CDK2_3	cd07860	0.00021	115	396
STKc_CDK1_euk	cd07861	0.00023	115	406
STKc_Nek1	cd08218	0.0002	115	377
STKc_Nek11	cd08222	8e-05	115	377
STKc_Nek7	cd08229	1.5e-06	115	382
STKc_Nek4	cd08223	0.00085	115	381
PTKc_Axl_like	cd05035	1.5e-39	116	381
PTKc_Tyro3	cd05074	1.6e-41	116	381
PTKc_Axl	cd05075	7.9e-33	116	381
STKc_CDK1_like	cd07835	3.2e-05	116	406
STKc_BUR1	cd07866	0.00035	116	370
STKc_YSK4	cd06631	2.5e-10	117	376
STKc_CDK_like	cd07829	6e-09	117	370
STKc_CCRK	cd07832	2.5e-08	117	371
STKc_CDK9_like	cd07840	6.6e-06	117	370
STKc_Nek	cd08215	1.1e-11	117	377
PTKc_Tyk2_rpt2	cd05080	6.2e-17	118	382
STKc_PKA	cd05580	0.00053	118	417
STKc_MEKK3_like	cd06625	3.9e-10	118	379
STKc_MEKK4	cd06626	2.1e-07	118	373
STKc_MEKK1	cd06630	1.9e-06	118	371
STKc_MEKK1_plant	cd06632	2.6e-10	118	373
STKc_NAK1_like	cd06917	1.6e-10	118	381
STKc_CDK7	cd07841	8.4e-09	118	374
STKc_Nek8	cd08220	8.7e-06	118	377
PTKc_Srm_Brk	cd05148	2.8e-38	119	380
STKc_PDK1	cd05581	4.7e-07	119	370
STKc_SLK_like	cd06611	8.2e-08	119	393
STKc_Cdc7_like	cd06627	2.7e-13	119	370
STKc_MAK_like	cd07830	4e-08	119	370
STKc_CDK4_6_like	cd07838	4.5e-07	119	370
STKc_TDY_MAPK_plant	cd07859	0.00082	119	416
PTKc	cd00192	1.4e-90	120	378
PTK_Jak_rpt1	cd05037	3.9e-13	120	374
PTKc_Ack_like	cd05040	1.4e-103	120	379
PTKc_Fes_like	cd05041	1.7e-30	120	379
PTKc_Aatyk	cd05042	2.5e-10	120	379
PTKc_Tie	cd05047	7.8e-17	120	378
PTKc_c-ros	cd05044	6.1e-32	120	379
PTKc_Met_Ron	cd05058	6.1e-42	120	383
PTKc_Syk_like	cd05060	3.1e-58	120	382
PTK_Jak1_rpt1	cd05077	1.2e-06	120	378
PTKc_Jak2_Jak3_rpt2	cd05081	9.9e-31	120	381
PTKc_Fes	cd05084	1.1e-41	120	379
PTKc_Fer	cd05085	2.7e-38	120	379
PTKc_Aatyk2	cd05086	2.3e-07	120	379
PTKc_Aatyk1_Aatyk3	cd05087	7.4e-08	120	379
PTK_Jak2_Jak3_rpt1	cd05078	3.3e-13	120	378
PTKc_Syk	cd05116	2.7e-44	120	382
STKc_CMGC	cd05118	6.8e-08	120	370
STKc_PKB	cd05571	0.00025	120	438
STKc_RSK_N	cd05582	0.00083	120	436
STKc_PKB_beta	cd05595	0.001	120	470
STKc_nPKC_theta	cd05619	0.00022	120	438
STKc_OSR1_SPAK	cd06610	1.4e-09	120	373
PKc_MKK4	cd06616	0.00019	120	392
STKc_CDKL	cd07833	0.00017	120	370
STKc_MAPK	cd07834	4e-06	120	409
STKc_CDK5	cd07839	0.00067	120	370
STKc_Nek2	cd08217	1.9e-05	120	379
STKc_FA2-like	cd08529	5.3e-07	120	381
STKc_CNK2-like	cd08530	1.1e-05	120	382
STKc_Nek9	cd08221	0.00012	121	378
PKc	cd00180	1.4e-47	122	377
PTKc_Zap-70	cd05115	5.7e-46	122	382
STKc_AGC	cd05123	8.3e-06	122	370
STKc_CDK4	cd07863	5.3e-05	122	419
STKc_CDC2L1	cd07843	6.8e-06	124	370
STKc_PKC	cd05570	0.00019	186	436
Pkinase	pfam00069	7.8e-27	116	373
Pkinase_Tyr	pfam07714	1.9e-116	116	377
TyrKc	smart00219	2.2e-112	116	377
STYKc	smart00221	9.7e-41	116	391
S_TKc	smart00220	1.4e-33	126	381

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041866	Polymorphism	p.ARG539CYS	N/A
Swiss-Prot	VAR_041864	Polymorphism	p.ARG339LYS	N/A
Swiss-Prot	VAR_041867	Polymorphism	p.SER546CYS	N/A
Swiss-Prot	VAR_041865	Polymorphism	p.THR514LYS	N/A
Swiss-Prot	VAR_041863	Polymorphism	p.VAL278ILE	N/A
Swiss-Prot	VAR_041868	Polymorphism	p.VAL598MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258