Results for the protein: Q6IQ55

Results for the Protein: Q6IQ55

116242833

146057

TTBK2

NCBI, UniProt

TTBK2_HUMAN RecName: Full=Tau-tubulin kinase 2

			0 13 0 2 11

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Swiss-Prot Protein: Q6IQ55

Identical to: NP_775771

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PKc_MKK7	cd06618	0.0004	4	304
STKc_PAK_I	cd06647	0.00042	4	302
STKc_PAK2	cd06655	0.00042	6	305
STKc_PAK3	cd06656	0.0002	6	306
STKc_PAK	cd06614	2.7e-06	6	259
STKc_CDK9	cd07865	2.7e-05	6	268
STKc_JNK	cd07850	0.001	7	357
STKc_p38gamma_MAPK12	cd07880	0.00019	7	323
STKc_p38beta_MAPK11	cd07878	0.00034	7	356
STKc_ASK	cd06624	4.3e-06	11	281
STKc_p38	cd07851	0.00018	11	294
STKc_BUR1	cd07866	5.4e-05	13	268
PTKc_ALK_LTK	cd05036	0.0003	14	264
STKc_CDK12	cd07864	9.8e-06	14	281
PTKc_Csk	cd05082	0.00038	15	283
PTKc_Chk	cd05083	0.00011	15	283
PTKc_Abl	cd05052	1.2e-05	16	284
PTKc_FAK	cd05056	0.00031	16	288
PTKc_Lck_Blk	cd05067	0.00086	16	297
PTKc_Lyn	cd05072	9.1e-06	16	283
PTKc_Hck	cd05073	8.2e-05	16	283
PTKc_Frk_like	cd05068	4.2e-07	16	283
PTKc_Itk	cd05112	8.2e-05	16	281
PTKc_Btk_Bmx	cd05113	0.00041	16	280
STKc_MAP4K3_like	cd06613	0.0002	17	255
STKc_CDC2L1	cd07843	0.00042	17	268
STKc_CDK10	cd07845	0.00018	17	333
PTKc_Src_like	cd05034	9.9e-07	18	283
PTKc_Srm_Brk	cd05148	0.00019	18	265
STKc_MST4	cd06640	7.2e-05	18	299
STKc_MST3	cd06641	0.00017	18	288
STKc_STK25-YSK1	cd06642	5.1e-05	18	299
STKc_MEKK2	cd06652	4.5e-05	18	282
STKc_MEKK3_like_1	cd06653	2.3e-05	18	282
STKc_ROCK_NDR_like	cd05573	0.001	19	298
STKc_PDK1	cd05581	2.4e-07	19	296
STKc_MST3_like	cd06609	3.6e-05	19	246
PKc_MAPKK	cd06605	0.0003	19	282
PKc_MAPKK_plant_like	cd06623	0.00014	19	286
STKc_MEKK3_like	cd06625	2.4e-08	19	281
PKc_MKK3_6	cd06617	0.00082	19	303
STKc_NAK1_like	cd06917	0.00092	19	266
STKc_CDKL	cd07833	5.6e-05	19	268
STKc_CdkB_plant	cd07837	7e-06	19	296
STKc_CDKL2_3	cd07846	4.4e-05	19	295
STKc_CDKL1_4	cd07847	8.7e-05	19	321
STKc_Nek6	cd08228	0.0001	19	289
STKc_Nek7	cd08229	1.1e-05	19	288
SPS1	COG0515	2.6e-30	19	477
PKc_STE	cd05122	3.3e-09	20	280
STKc_GRK4_like	cd05605	0.00052	20	335
STKc_MAPKKK	cd06606	3.5e-13	20	281
STKc_MEKK4	cd06626	3.2e-07	20	256
STKc_Cdc7_like	cd06627	1.4e-05	20	251
STKc_MAPKKK_Byr2_lik	cd06628	2.6e-07	20	281
STKc_MEKK1	cd06630	3.5e-06	20	256
STKc_YSK4	cd06631	8.6e-07	20	281
STKc_MEKK1_plant	cd06632	0.00026	20	251
STKc_MEKK3	cd06651	1.7e-07	20	283
STKc_CCRK	cd07832	3.1e-07	20	269
STKc_CDK7	cd07841	0.00037	20	276
STKc_Nek	cd08215	5.2e-05	20	268
STKc_Nek2	cd08217	0.00035	20	281
STKc_Nek3	cd08219	9.4e-06	20	285
STKc_Nek5	cd08225	3.1e-05	20	285
STKc_CMGC	cd05118	1.8e-05	21	268
STKc_CDK_like	cd07829	4.6e-07	21	268
STKc_MOK	cd07831	7.4e-05	21	268
STKc_CDK9_like	cd07840	7.2e-06	21	268
STKc_MAK_like	cd07830	5.6e-05	21	209
PTKc	cd00192	0.0004	25	281
PKc	cd00180	9e-40	27	279
STKc_AGC	cd05123	6e-05	27	296
STKc_cGK_PKG	cd05572	0.00095	27	262
STKc_MAST_like	cd05579	0.00027	27	297
STKc_MAPKKK_Bck1_lik	cd06629	2.3e-05	27	281
Pkinase	pfam00069	2.2e-14	21	279
Pkinase_Tyr	pfam07714	2.9e-05	21	265
STYKc	smart00221	5.8e-20	21	268
TyrKc	smart00219	7.3e-06	21	265
S_TKc	smart00220	2.2e-13	31	281

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041262	Polymorphism	p.ARG120GLN	N/A
Swiss-Prot	VAR_069053	Polymorphism	p.ARG1110HIS	N/A
dbSNP	rs56039839	Polymorphism	p.ARG500PRO	N/A
Swiss-Prot	VAR_041266	Polymorphism	p.ASP635GLY	N/A
Swiss-Prot	VAR_069052	Polymorphism	p.GLU842GLY	N/A
dbSNP	rs6493068	Polymorphism	p.LEU8PRO	N/A
Swiss-Prot	VAR_041271	Polymorphism	p.LYS1241THR	N/A
Swiss-Prot	VAR_041270	Polymorphism	p.PRO1122ARG	N/A
Swiss-Prot	VAR_041263	Polymorphism	p.THR313ALA	N/A
Swiss-Prot	VAR_041267	Polymorphism	p.THR1062ILE	N/A
Swiss-Prot	VAR_041268	Polymorphism	p.THR1084MET	N/A
Swiss-Prot	VAR_041269	Polymorphism	p.VAL1097ALA	N/A
Swiss-Prot	VAR_041264	Polymorphism	p.VAL440MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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