Results for the protein: Q8N2I9

Results for the Protein: Q8N2I9

116256080

83931

STK40

NCBI, UniProt

STK40_HUMAN RecName: Full=Serine/threonine-protein kinase 40; AltName: Full=SINK-homologous serine/threonine-protein kinase; AltName: Full=Sugen kinase 495; Short=SgK495

			0 4 0 1 3

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Swiss-Prot Protein: Q8N2I9

Identical to: NP_114406

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_MEKK2	cd06652	0.00036	32	331
SPS1	COG0515	1e-27	33	432
STKc_MAPKKK	cd06606	4e-09	34	325
STKc_Nek11	cd08222	1.1e-05	35	330
STKc_PAK5	cd06658	0.00048	40	355
PKc	cd00180	3.7e-55	41	328
STKc_beta_ARK	cd05606	0.00029	41	350
STKc_PAK6	cd06659	0.00079	41	361
STKc_ROCK2	cd05621	6e-05	43	392
STKc_CMGC	cd05118	1.3e-05	48	326
PKc_MAPKK_plant_like	cd06623	8.2e-08	48	337
STKc_AGC	cd05123	1.8e-14	49	324
STKc_phototropin_lik	cd05574	8.4e-08	50	333
STKc_NDR_like	cd05599	5e-06	53	379
STKc_Rim15_like	cd05611	6.2e-06	53	336
STKc_Nek	cd08215	1.4e-13	53	332
STKc_ROCK	cd05596	9.5e-05	57	380
STKc_PAK1	cd06654	0.00038	59	357
STKc_DMPK_like	cd05597	1.2e-05	60	397
STKc_MAST	cd05609	5.8e-08	60	394
STKc_MRCK_alpha	cd05623	0.00025	60	391
STKc_MRCK_beta	cd05624	5.7e-05	60	391
STKc_LATS2	cd05626	0.00068	60	404
STKc_NDR2	cd05627	0.00031	60	409
STKc_NDR1	cd05628	0.00016	60	384
STKc_PAK3	cd06656	0.0004	60	358
STKc_CdkB_plant	cd07837	9.4e-05	60	331
STKc_cPKC	cd05587	4.1e-08	61	382
STKc_GRK4_like	cd05605	2.4e-06	61	351
STKc_MSK1_N	cd05613	8.9e-06	61	349
STKc_MSK2_N	cd05614	2.4e-06	61	394
STKc_cPKC_beta	cd05616	4.5e-07	61	382
STKc_GRK6	cd05630	9.2e-06	61	349
STKc_GRK4	cd05631	3.9e-05	61	351
STKc_GRK5	cd05632	2.3e-05	61	351
STKc_CDKL1_4	cd07847	0.00016	61	364
STKc_p38gamma_MAPK12	cd07880	0.00052	62	375
STKc_CNK2-like	cd08530	2.7e-08	64	331
STKc_Nek10	cd08528	8.9e-06	64	334
STKc_RSK_N	cd05582	0.00036	65	399
STKc_PKN	cd05589	3.5e-07	65	399
STKc_Nek7	cd08229	3.2e-06	65	333
STKc_Nek1	cd08218	4.5e-05	66	332
STKc_ASK	cd06624	0.00012	72	330
STKc_GRK1	cd05608	6.9e-07	73	350
STKc_MAPKKK_Byr2_lik	cd06628	0.00019	73	330
STKc_PCTAIRE_like	cd07844	0.00051	74	366
STKc_cPKC_alpha	cd05615	3.6e-07	75	382
STKc_CDK9_like	cd07840	8.4e-05	79	328
STKc_Nek6	cd08228	2.9e-05	80	333
STKc_nPKC_eta	cd05590	1.5e-06	82	382
STKc_PKB_alpha	cd05594	1.7e-09	82	395
STKc_SGK2	cd05603	4.3e-07	82	400
STKc_PRKX_like	cd05612	7.3e-07	82	362
STKc_MEKK3	cd06651	2.8e-05	82	332
STKc_MEKK3_like	cd06625	8.8e-07	84	330
STKc_Nek5	cd08225	0.00027	84	330
STKc_p70S6K	cd05584	1.4e-05	86	401
PKc_MKK7	cd06618	0.00018	86	334
STKc_CDK10	cd07845	0.00073	86	352
STKc_PKB	cd05571	3.2e-11	87	395
STKc_SGK	cd05575	4.7e-06	87	399
STKc_aPKC	cd05588	2.7e-06	87	380
STKc_nPKC_epsilon	cd05591	7.9e-07	87	382
STKc_nPKC_theta_delt	cd05592	1.2e-07	87	400
STKc_PKB_gamma	cd05593	9.2e-08	87	390
STKc_PKB_beta	cd05595	3.2e-08	87	394
STKc_SGK1	cd05602	2.1e-05	87	409
STKc_SGK3	cd05604	9.4e-05	87	409
STKc_aPKC_zeta	cd05617	3.7e-06	87	380
STKc_aPKC_iota	cd05618	7.1e-05	87	380
STKc_nPKC_theta	cd05619	2.6e-07	87	383
STKc_YPK1_like	cd05585	8.4e-07	89	380
STKc_Sck1_like	cd05586	1.3e-06	89	432
STKc_MST1_2	cd06612	6e-07	90	328
STKc_ERK1_2_like	cd07849	0.0002	90	380
STKc_PAK_II	cd06648	1.2e-06	91	345
STKc_Nek6_Nek7	cd08224	2.4e-05	91	333
STKc_PKA	cd05580	3.7e-10	92	366
STKc_CDKL2_3	cd07846	4.8e-06	92	330
STKc_MSK_N	cd05583	2.3e-07	93	349
STKc_CDK7	cd07841	0.00074	93	329
STKc_Nek3	cd08219	1.8e-06	93	330
STKc_Nek4	cd08223	0.00014	93	330
STKc_FA2-like	cd08529	6.7e-07	93	331
STKc_MOK	cd07831	0.00012	94	326
STKc_LATS	cd05598	4.5e-06	95	404
STKc_PAK	cd06614	9.9e-06	96	332
PKc_MKK3_6	cd06617	0.00053	97	341
STKc_p38	cd07851	8e-05	100	375
STKc_MEKK1	cd06630	0.00019	101	329
STKc_CRIK	cd05601	7.7e-06	103	379
STKc_YSK4	cd06631	9.7e-05	103	330
STKc_NAK1_like	cd06917	0.00036	105	349
STKc_Nek8	cd08220	6.7e-07	105	333
STKc_Sid2p_Dbf2p	cd05600	9.2e-05	107	401
STKc_PDK1	cd05581	6.5e-13	108	326
PTKc	cd00192	0.00014	109	329
STKc_Nek9	cd08221	2.6e-08	110	330
STKc_ROCK_NDR_like	cd05573	1.6e-09	111	391
PKc_STE	cd05122	4.1e-07	112	326
STKc_CDK_like	cd07829	2.7e-06	116	328
STKc_cGK_PKG	cd05572	2.1e-06	117	337
STKc_Cdc7_like	cd06627	0.00045	117	326
STKc_CCRK	cd07832	1e-06	117	331
STKc_Nek2	cd08217	2.2e-07	117	330
STKc_PKC	cd05570	1.3e-10	120	379
STKc_Yank1	cd05578	1.6e-09	120	331
STKc_GRK	cd05577	5.1e-07	121	350
STKc_MAPK15	cd07852	9.9e-05	121	370
STKc_MEKK1_plant	cd06632	0.0001	132	326
STKc_MAST_like	cd05579	2.9e-10	149	326
STKc_MEKK4	cd06626	1.9e-05	156	330
Pkinase	pfam00069	2e-32	35	328
STYKc	smart00221	3e-17	35	330
S_TKc	smart00220	1.9e-36	46	332
Pkinase_Tyr	pfam07714	4.1e-05	68	328
TyrKc	smart00219	2e-06	94	328

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs3795498	Polymorphism	p.ALA395THR	N/A
Swiss-Prot	VAR_041200	Polymorphism	p.ALA10VAL	N/A
Swiss-Prot	VAR_041202	Polymorphism	p.ARG211GLN	N/A
Swiss-Prot	VAR_041201	Polymorphism	p.MET133THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258