Results for the protein: P03956

Results for the Protein: P03956

116852

4312

MMP1

NCBI, UniProt

MMP1_HUMAN RecName: Full=Interstitial collagenase; AltName: Full=Fibroblast collagenase; AltName: Full=Matrix metalloproteinase-1; Short=MMP-1; Contains: RecName: Full=22 kDa interstitial collagenase; Contains: RecName: Full=27 kDa interstitial collagenase; Flags: Precursor

			0 6 0 0 6

Tips:

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Default View: PG_binding_1 - pfam01471 ZnMc - smart00235 Peptidase_M10 - pfam00413 ZnMc_MMP - cd04278 ZnMc_MMP_like_1 - cd04279 ZnMc_MMP_like - cd04268 ZnMc_serralysin_like - cd04277 ZnMc - cd00203 HX - cd00094 HX - smart00120 Hemopexin - pfam00045	Swiss-Prot Protein: P03956 Identical to: NP_002412 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ZnMc_MMP_like	cd04268	1e-06	111	260
ZnMc_serralysin_like	cd04277	1.1e-07	111	261
ZnMc_MMP_like_1	cd04279	4.8e-12	111	261
ZnMc	cd00203	8.5e-20	112	260
HX	cd00094	1.3e-99	275	466
PG_binding_1	pfam01471	1.9e-13	27	87
Peptidase_M10	pfam00413	1.2e-93	108	261
Hemopexin	pfam00045	1.1e-09	284	326
Hemopexin	pfam00045	2.5e-13	328	372
Hemopexin	pfam00045	4.8e-21	377	424
Hemopexin	pfam00045	2.1e-07	426	466
ZnMc	smart00235	6.2e-56	105	262
HX	smart00120	3.5e-08	284	326
HX	smart00120	9.7e-13	328	372
HX	smart00120	7.9e-20	377	424
HX	smart00120	3.9e-07	426	466

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_021025	Polymorphism	p.ARG405GLN	N/A
Swiss-Prot	VAR_054005	Polymorphism	p.ARG262SER	N/A
Swiss-Prot	VAR_011970	Polymorphism	p.ASP252GLY	N/A
Swiss-Prot	VAR_011969	Polymorphism	p.GLN29PRO	N/A
Swiss-Prot	VAR_021024	Polymorphism	p.ILE191VAL	N/A
Swiss-Prot	VAR_021026	Polymorphism	p.SER406THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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