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Results for the Protein: P01189
116880

COLI_HUMAN RecName: Full=Pro-opiomelanocortin; Short=POMC; AltName: Full=Corticotropin-lipotropin; Contains: RecName: Full=NPP; Contains: RecName: Full=Melanotropin gamma; AltName: Full=Gamma-MSH; Contains: RecName: Full=Potential peptide; Contains: RecName: Full=Corticotropin; AltName: Full=Adrenocorticotropic hormone; Short=ACTH; Contains: RecName: Full=Melanotropin alpha; AltName: Full=Alpha-MSH; Contains: RecName: Full=Corticotropin-like intermediary peptide; Short=CLIP; Contains: RecName: Full=Lipotropin beta; AltName: Full=Beta-LPH; Contains: RecName: Full=Lipotropin gamma; AltName: Full=Gamma-LPH; Contains: RecName: Full=Melanotropin beta; AltName: Full=Beta-MSH; Contains: RecName: Full=Beta-endorphin; Contains: RecName: Full=Met-enkephalin; Flags: Precursor

Known Diseases associated with this Protein:
  OBESITY, EARLY-ONSET, SUSCEPTIBILITY TO
  PROOPIOMELANOCORTIN DEFICIENCY
3
8
3
0
8
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Default View:

NPP - pfam08384
Op_neuropeptide - pfam08035


Swiss-Prot Protein: P01189
Identical to: NP_001030333, NP_000930
   Default View:



Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Op_neuropeptidepfam080352.2e-14237265

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_012201Polymorphismp.ARG236GLNN/A
Swiss-ProtVAR_010701Polymorphismp.ARG236GLYN/A
Swiss-ProtVAR_010715Polymorphismp.ASP106ASNN/A
Swiss-ProtVAR_010716Polymorphismp.GLU214GLYN/A
Swiss-ProtVAR_029314Polymorphismp.PRO132ALAN/A
Swiss-ProtVAR_029762Polymorphismp.PRO62LEUN/A
Swiss-ProtVAR_010700Polymorphismp.SER9LEUN/A
Swiss-ProtVAR_010699Polymorphismp.SER7THRN/A
OMIM176830.0004 Diseasep.ARG236GLYOBESITY, EARLY-ONSET, SUSCEPTIBILITY TO
OMIM176830.0001 Diseasep.GLU79TERPROOPIOMELANOCORTIN DEFICIENCY
OMIM176830.0006 Diseasep.LYS25TERPROOPIOMELANOCORTIN DEFICIENCY



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