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Results for the Protein: P42345
1169735

MTOR_HUMAN RecName: Full=Serine/threonine-protein kinase mTOR; AltName: Full=FK506-binding protein 12-rapamycin complex-associated protein 1; AltName: Full=FKBP12-rapamycin complex-associated protein; AltName: Full=Mammalian target of rapamycin; Short=mTOR; AltName: Full=Mechanistic target of rapamycin; AltName: Full=Rapamycin and FKBP12 target 1; AltName: Full=Rapamycin target protein 1
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Default View:

TEL1 - COG5032
DUF3385 - pfam11865
FAT - pfam02259
Rapamycin_bind - pfam08771
PI3Kc_III - cd00896
PI3Kc - cd00891
PIKKc_ATM - cd05171
PIKKc_SMG1 - cd05170
PIKKc_DNA-PK - cd05172
PI3Kc_like - cd00142
PIKKc - cd05164
TRRAP - cd05163
PIKKc_TOR - cd05169
PIKKc_ATR - cd00892
PI3_PI4_kinase - pfam00454
PI3Kc - smart00146
FATC - pfam02260


Swiss-Prot Protein: P42345
Identical to: NP_004949
   Default View:















Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PI3Kc_IIIcd008961.6e-0520762429
PI3Kccd008917.9e-0620862441
PI3Kc_likecd001421e-12121532424
PIKKc_ATRcd008928.2e-8021532431
PIKKccd051646.1e-16321532424
TRRAPcd051638.9e-0921532431
PIKKc_TORcd051692.3e-21921532431
PIKKc_DNA-PKcd051722.5e-4421532431
PIKKc_SMG1cd051708.9e-5721532431
PIKKc_ATMcd051711.6e-4621532431
TEL1COG50323092549
FATpfam022598.8e-18015131908
PI3_PI4_kinasepfam004543.1e-10921812431
FATCpfam022602.2e-1925172549
DUF3385pfam118652.2e-918541024
Rapamycin_bindpfam087711.9e-7020152114
PI3Kcsmart001461.1e-11021832438

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041537Polymorphismp.ALA8SERN/A
Swiss-ProtVAR_041540Polymorphismp.ALA1134VALN/A
Swiss-ProtVAR_064733Polymorphismp.LEU2220PHEN/A
Swiss-ProtVAR_041538Polymorphismp.MET135THRN/A
Swiss-ProtVAR_041539Polymorphismp.MET1083VALN/A
Swiss-ProtVAR_041542Polymorphismp.MET2011VALN/A
Swiss-ProtVAR_041544Polymorphismp.PRO2476LEUN/A
Swiss-ProtVAR_041541Polymorphismp.SER1178PHEN/A
Swiss-ProtVAR_041543Polymorphismp.SER2215TYRN/A
Swiss-ProtVAR_064734Polymorphismp.VAL2406ALAN/A



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