Results for the protein: Q13163

Results for the Protein: Q13163

118572669

5607

MAP2K5

NCBI, UniProt

MP2K5_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 5; Short=MAP kinase kinase 5; Short=MAPKK 5; AltName: Full=MAPK/ERK kinase 5; Short=MEK 5

			0 3 0 0 3

Tips:

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Swiss-Prot Protein: Q13163

Identical to: NP_660143

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PB1	cd05992	9.5e-12	17	107
PB1_Map2k5	cd06395	2.1e-73	17	107
STKc_ROCK2	cd05621	3.9e-05	118	442
STKc_ROCK	cd05596	5.7e-05	131	425
STKc_myosinIIIB	cd06639	5.3e-20	140	420
STKc_TAO1	cd06635	1.2e-10	141	444
STKc_TAO3	cd06633	3.3e-09	142	445
PTKc_DDR2	cd05095	1.1e-06	144	421
PTKc_DDR_like	cd05097	1.2e-06	144	421
STKc_PAK1	cd06654	2.4e-11	144	444
STKc_PAK4	cd06657	2.5e-14	144	438
STKc_PAK5	cd06658	1.6e-13	144	436
STKc_PAK6	cd06659	6.3e-14	144	442
STKc_PAK_I	cd06647	1e-22	146	442
STKc_PAK2	cd06655	6.6e-16	146	445
STKc_PAK3	cd06656	4e-12	146	445
PTKc_FGFR1	cd05098	0.00034	148	428
STKc_TAO	cd06607	1.6e-14	149	447
STKc_TAO2	cd06634	4.5e-12	149	445
STKc_myosinIIIA	cd06638	1.2e-19	149	419
STKc_p38beta_MAPK11	cd07878	3.9e-05	149	446
STKc_PAK	cd06614	1.6e-33	150	430
STKc_MAP4K4_6	cd06636	2.5e-23	150	419
STKc_STK10_LOK	cd06644	1.2e-30	150	441
STKc_PAK_II	cd06648	2.3e-16	150	432
STKc_JNK2	cd07876	0.00026	150	443
STKc_p38alpha_MAPK14	cd07877	1.7e-05	150	446
STKc_JNK	cd07850	1.4e-05	151	446
STKc_p38	cd07851	1.1e-07	152	446
PTKc_PDGFR	cd05055	0.00045	154	400
PKc_MKK7	cd06618	8.7e-67	154	440
STKc_MAP4K5	cd06646	6.1e-22	154	418
STKc_p38gamma_MAPK12	cd07880	1.2e-05	154	446
PTKc_FGFR4	cd05099	0.00011	155	448
STKc_CDK9	cd07865	2.3e-07	155	419
PTKc_FGFR2	cd05101	0.00022	156	428
STKc_ASK	cd06624	6e-27	157	419
STKc_PCTAIRE1	cd07873	9.8e-07	157	431
STKc_PCTAIRE2	cd07872	1.2e-07	157	436
PTKc_Tie2	cd05088	7.2e-06	158	440
PTKc_VEGFR2	cd05103	5.9e-05	158	423
PTKc_VEGFR3	cd05102	0.00023	158	426
STKc_PCTAIRE_like	cd07844	1.6e-07	158	434
PTKc_ALK_LTK	cd05036	3.9e-09	159	419
STKc_MAP4K3	cd06645	2.5e-25	159	418
STKc_Sty1_Hog1	cd07856	3.8e-08	159	440
STKc_CDK12	cd07864	4.2e-08	159	419
STKc_BUR1	cd07866	2.5e-05	159	419
STKc_PCTAIRE3	cd07871	1.3e-07	159	437
PTK_CCK4	cd05046	0.00032	160	416
PTKc_Ror	cd05048	9.8e-06	160	398
PTKc_Trk	cd05049	2e-08	160	416
PTKc_Musk	cd05050	8.2e-08	160	422
PTKc_Abl	cd05052	6.6e-09	160	418
PTKc_FAK	cd05056	1.3e-08	160	425
PTKc_DDR	cd05051	8.3e-06	160	421
PTKc_InsR	cd05061	2.5e-05	160	422
PTKc_IGF-1R	cd05062	0.00024	160	421
PTKc_EphR_A10	cd05064	3.5e-06	160	423
PTKc_Lck_Blk	cd05067	2.8e-06	160	422
PTKc_Frk_like	cd05068	9.3e-15	160	422
PTKc_Yes	cd05069	1.2e-07	160	422
PTKc_Fyn_Yrk	cd05070	8.1e-07	160	422
PTKc_Src	cd05071	9.1e-07	160	424
PTKc_EphR_A2	cd05063	2.4e-06	160	419
PTKc_Hck	cd05073	8.6e-07	160	422
PTKc_Csk	cd05082	1e-07	160	420
PTKc_Ror1	cd05090	5.3e-05	160	422
PTKc_Lyn	cd05072	4.5e-07	160	422
PTKc_TrkA	cd05092	3.5e-06	160	421
PTKc_TrkB	cd05093	3.6e-06	160	431
PTKc_TrkC	cd05094	3e-05	160	433
PTKc_Ror2	cd05091	0.00081	160	422
PTKc_DDR1	cd05096	9.7e-05	160	421
PKc_MAPKK_Byr1_like	cd06620	4.8e-106	160	434
STKc_SLK	cd06643	2.5e-22	160	437
PKc_MEK2	cd06649	4.6e-75	160	447
PKc_MEK1	cd06650	8.3e-76	160	446
PTKc_InsR_like	cd05032	9.8e-10	161	417
PTKc_EphR	cd05033	6.4e-08	161	419
PTKc_Src_like	cd05034	4.7e-11	161	422
PTKc_Jak_rpt2	cd05038	1.7e-09	161	421
PTKc_Csk_like	cd05039	1.7e-07	161	420
PTK_Ryk	cd05043	0.00039	161	382
PTKc_FGFR	cd05053	2.6e-05	161	421
PTKc_EGFR_like	cd05057	1.6e-08	161	432
PTKc_Tec_like	cd05059	1.3e-07	161	418
PTKc_EphR_B	cd05065	5.2e-07	161	419
PTKc_EphR_A	cd05066	1e-05	161	419
PTKc_Jak2_Jak3_rpt2	cd05081	6.7e-09	161	421
PTKc_Chk	cd05083	2.6e-07	161	420
PTKc_EGFR	cd05108	1.9e-07	161	436
PTKc_HER2	cd05109	1.3e-08	161	432
PTKc_HER4	cd05110	8.2e-06	161	424
PTK_HER3	cd05111	3.1e-07	161	432
PTKc_Itk	cd05112	6.7e-09	161	418
PTKc_Tec_Rlk	cd05114	2.1e-07	161	418
PTKc_Btk_Bmx	cd05113	8e-10	161	418
PKc_MKK4	cd06616	1.8e-72	161	438
STKc_Nek6_Nek7	cd08224	4.3e-12	161	428
STKc_MST1_2	cd06612	1.2e-40	162	419
STKc_MAP4K3_like	cd06613	3.2e-48	162	418
STKc_ERK5	cd07855	1.3e-05	162	441
STKc_PFTAIRE1	cd07869	0.00034	162	424
STKc_PFTAIRE2	cd07870	3.7e-06	162	434
PTKc_Jak1_rpt2	cd05079	4.3e-05	163	420
STKc_MST4	cd06640	7.9e-42	163	441
STKc_MST3	cd06641	4.8e-37	163	434
STKc_STK25-YSK1	cd06642	3.3e-42	163	441
STKc_MEKK2	cd06652	1e-09	163	420
STKc_MEKK3_like_1	cd06653	2.7e-17	163	419
STKc_ERK1_2_like	cd07849	1.6e-07	163	445
STKc_MAPK15	cd07852	3.2e-07	163	433
STKc_TEY_MAPK_plant	cd07858	3.2e-06	163	447
PTKc_Tie1	cd05089	2.4e-06	164	448
STKc_ROCK_NDR_like	cd05573	1.2e-08	164	447
STKc_phototropin_lik	cd05574	3.5e-08	164	383
STKc_PKA	cd05580	7.3e-10	164	433
STKc_PDK1	cd05581	4.3e-15	164	419
STKc_DMPK_like	cd05597	0.0004	164	448
STKc_CRIK	cd05601	2.7e-07	164	448
STKc_MAST	cd05609	5.2e-07	164	448
STKc_PRKX_like	cd05612	1.2e-06	164	447
STKc_NDR1	cd05628	0.00073	164	444
STKc_MRCK_alpha	cd05623	0.00092	164	436
PKc_MAPKK	cd06605	2.3e-188	164	424
STKc_OSR1_SPAK	cd06610	5.6e-24	164	419
PKc_MEK	cd06615	5.4e-107	164	438
PKc_MKK3_6	cd06617	3.7e-82	164	439
PKc_MKK5	cd06619	8.3e-222	164	442
PKc_MAPKK_Pek1_like	cd06621	3e-88	164	430
PKc_MAPKK_PBS2_like	cd06622	9.3e-88	164	441
PKc_MAPKK_plant_like	cd06623	5.9e-98	164	425
STKc_MAPKKK_Byr2_lik	cd06628	3.9e-26	164	419
STKc_NAK1_like	cd06917	6.8e-19	164	438
STKc_CdkB_plant	cd07837	1.8e-09	164	420
STKc_CDKL5	cd07848	6.8e-05	164	419
STKc_MAPK4_6	cd07854	1.8e-05	164	441
STKc_CDK6	cd07862	0.00021	164	443
STKc_Nek6	cd08228	2.9e-12	164	428
STKc_Nek7	cd08229	3e-12	164	419
STKc_Nek9	cd08221	6.8e-11	164	419
SPS1	COG0515	1.5e-30	164	447
PTKc_RET	cd05045	1.2e-05	165	417
PKc_STE	cd05122	7e-76	165	418
STKc_Yank1	cd05578	5.1e-16	165	419
STKc_MSK_N	cd05583	3.9e-09	165	435
STKc_cPKC	cd05587	1.7e-05	165	445
STKc_GRK4_like	cd05605	8.4e-10	165	447
STKc_MSK1_N	cd05613	2.2e-06	165	436
STKc_cPKC_alpha	cd05615	6.6e-05	165	431
STKc_cPKC_beta	cd05616	0.00046	165	420
STKc_MSK2_N	cd05614	1.1e-05	165	447
STKc_GRK6	cd05630	1.8e-06	165	438
STKc_GRK4	cd05631	8.7e-07	165	438
STKc_GRK5	cd05632	1.8e-06	165	437
STKc_MAPKKK	cd06606	7.6e-46	165	419
STKc_Cdc7_like	cd06627	3e-24	165	419
STKc_MEKK3	cd06651	4.6e-16	165	421
STKc_Pho85	cd07836	3.5e-07	165	434
STKc_NLK	cd07853	9.6e-05	165	448
STKc_CDK2_3	cd07860	9.3e-07	165	437
STKc_CDK1_euk	cd07861	3.3e-06	165	419
STKc_Nek	cd08215	2.9e-26	165	419
PK_STRAD	cd08216	7.3e-10	165	435
STKc_Nek3	cd08219	3.2e-12	165	419
STKc_Nek4	cd08223	1.4e-07	165	419
PK_STRAD_alpha	cd08227	8.7e-06	165	436
PK_STRAD_beta	cd08226	4.1e-05	165	435
STKc_FA2-like	cd08529	1.8e-16	165	419
STKc_CNK2-like	cd08530	2.8e-15	165	419
PTKc_Axl_like	cd05035	2.1e-05	166	421
PTKc_Tyro3	cd05074	6.2e-05	166	421
PTKc_Axl	cd05075	0.00075	166	421
STKc_PKN	cd05589	1.2e-06	166	445
STKc_MST3_like	cd06609	4.5e-37	166	434
STKc_CDK1_like	cd07835	4.4e-07	166	434
PTKc_Tyk2_rpt2	cd05080	1.3e-05	167	424
PTKc_Srm_Brk	cd05148	4.1e-08	167	416
STKc_MEKK3_like	cd06625	4.2e-26	167	419
STKc_CCRK	cd07832	1.8e-13	167	420
STKc_MAPK	cd07834	1e-09	167	440
STKc_CDK5	cd07839	1.8e-08	167	419
STKc_CDK7	cd07841	8.9e-10	167	420
STKc_CDK8_like	cd07842	0.00017	167	419
STKc_CDKL2_3	cd07846	5.6e-11	167	419
STKc_CDKL1_4	cd07847	2.5e-19	167	419
STKc_MPK1	cd07857	1.3e-05	167	441
STKc_TDY_MAPK_plant	cd07859	1.5e-05	167	448
STKc_CDK4	cd07863	3.9e-06	167	419
STKc_Nek1	cd08218	2.4e-08	167	419
STKc_Nek8	cd08220	2.1e-09	167	419
STKc_Nek11	cd08222	6.8e-14	167	419
STKc_Nek5	cd08225	8.9e-18	167	419
STKc_Nek10	cd08528	5.6e-08	167	419
STKc_CMGC	cd05118	7.5e-16	168	419
STKc_TNIK	cd06637	2.1e-24	168	419
STKc_CDK_like	cd07829	3.9e-14	168	419
STKc_MAK_like	cd07830	4.5e-08	168	419
STKc_MOK	cd07831	2.7e-08	168	419
STKc_CDK9_like	cd07840	1.2e-09	168	419
STKc_RSK_N	cd05582	4.2e-05	169	445
STKc_p70S6K	cd05584	0.0001	169	447
STKc_MEKK4	cd06626	4.6e-18	169	419
PTKc	cd00192	5.7e-12	170	418
PTK_Jak_rpt1	cd05037	0.0003	170	414
PTKc_Ack_like	cd05040	4e-11	170	415
PTKc_Aatyk	cd05042	9.8e-05	170	416
PTKc_c-ros	cd05044	1e-06	170	415
PTKc_Tie	cd05047	0.00012	170	427
PTKc_Fes_like	cd05041	2.1e-10	170	419
PTKc_Met_Ron	cd05058	3.7e-05	170	423
PTK_Jak2_Jak3_rpt1	cd05078	7.2e-06	170	423
PTKc_Fes	cd05084	7.3e-08	170	419
PTKc_Fer	cd05085	1.3e-08	170	419
PTKc_Syk_like	cd05060	2.3e-07	170	424
PTKc_Syk	cd05116	8.7e-06	170	419
STKc_PKC	cd05570	9.4e-11	170	434
STKc_PKB	cd05571	4.4e-06	170	447
STKc_SGK	cd05575	2e-05	170	447
STKc_aPKC	cd05588	1.1e-06	170	445
STKc_nPKC_eta	cd05590	4.5e-05	170	446
STKc_nPKC_epsilon	cd05591	6.7e-06	170	446
STKc_nPKC_theta_delt	cd05592	1.6e-05	170	447
STKc_PKB_gamma	cd05593	1.9e-05	170	448
STKc_PKB_alpha	cd05594	2.2e-05	170	444
STKc_PKB_beta	cd05595	0.00013	170	448
STKc_SGK2	cd05603	6.6e-06	170	448
STKc_SGK3	cd05604	3.7e-05	170	448
STKc_SGK1	cd05602	2.7e-05	170	448
STKc_aPKC_zeta	cd05617	1.5e-06	170	445
STKc_aPKC_iota	cd05618	9.8e-05	170	445
STKc_nPKC_theta	cd05619	4e-06	170	447
STKc_myosinIII_like	cd06608	2.6e-24	170	419
STKc_MEKK1	cd06630	2.2e-13	170	420
STKc_YSK4	cd06631	2.3e-15	170	419
STKc_CDK4_6_like	cd07838	4.7e-08	170	419
STKc_CDK10	cd07845	1.1e-05	170	417
STKc_Nek2	cd08217	1.9e-14	170	419
PTKc_Zap-70	cd05115	2.9e-06	171	422
STKc_beta_ARK	cd05606	8.3e-08	171	440
STKc_GRK3	cd05633	3e-06	171	441
STKc_CDKL	cd07833	1.3e-12	171	419
PKc	cd00180	2.1e-67	172	417
STKc_AGC	cd05123	3.7e-16	172	419
STKc_cGK_PKG	cd05572	1.5e-15	172	426
STKc_GRK	cd05577	2.7e-09	172	424
STKc_MAST_like	cd05579	1.3e-15	172	424
STKc_YPK1_like	cd05585	7.4e-05	172	447
STKc_Sck1_like	cd05586	0.00095	172	448
STKc_GRK1	cd05608	2.5e-10	172	437
STKc_GRK7	cd05607	1.2e-07	172	436
STKc_SLK_like	cd06611	3.3e-17	172	436
STKc_MEKK1_plant	cd06632	7.4e-18	172	419
STKc_MAPKKK_Bck1_lik	cd06629	1.6e-13	173	419
STKc_CDC2L1	cd07843	3.4e-07	178	419
PB1	pfam00564	1.6e-14	18	97
Pkinase	pfam00069	9.7e-69	166	419
PB1	smart00666	3e-12	18	95
Pkinase_Tyr	pfam07714	1.5e-16	166	419
TyrKc	smart00219	5.1e-15	166	417
STYKc	smart00221	3.6e-62	166	419
S_TKc	smart00220	7.2e-67	176	419
KIND	smart00750	1e-06	247	427

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_046070	Polymorphism	p.ALA428THR	N/A
Swiss-Prot	VAR_040824	Polymorphism	p.ALA427VAL	N/A
Swiss-Prot	VAR_040823	Polymorphism	p.HIS118ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258