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Results for the Protein: Q13163
118572669

MP2K5_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 5; Short=MAP kinase kinase 5; Short=MAPKK 5; AltName: Full=MAPK/ERK kinase 5; Short=MEK 5
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 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

PTKc_PDGFR_alpha - cd05105
PB1_Map2k5 - cd06395
PB1 - cd05992
PB1 - smart00666
PB1 - pfam00564
STKc_ROCK2 - cd05621
STKc_ROCK - cd05596
STKc_myosinIIIB - cd06639
STKc_TAO1 - cd06635
STKc_TAO3 - cd06633
PTKc_DDR_like - cd05097
PTKc_DDR2 - cd05095
STKc_PAK6 - cd06659
STKc_PAK5 - cd06658
STKc_PAK4 - cd06657
STKc_PAK1 - cd06654
STKc_PAK3 - cd06656
STKc_PAK_I - cd06647
STKc_PAK2 - cd06655
PTKc_FGFR1 - cd05098
STKc_p38beta_MAPK11 - cd07878
STKc_TAO - cd06607
STKc_TAO2 - cd06634
STKc_myosinIIIA - cd06638
STKc_p38alpha_MAPK14 - cd07877
STKc_JNK2 - cd07876
STKc_STK10_LOK - cd06644
STKc_PAK_II - cd06648
STKc_MAP4K4_6 - cd06636
STKc_PAK - cd06614
STKc_JNK - cd07850
STKc_p38 - cd07851
STKc_p38gamma_MAPK12 - cd07880
STKc_MAP4K5 - cd06646
PKc_MKK7 - cd06618
PTKc_PDGFR - cd05055
STKc_CDK9 - cd07865
PTKc_FGFR4 - cd05099
PTKc_FGFR2 - cd05101
STKc_PCTAIRE1 - cd07873
STKc_PCTAIRE2 - cd07872
STKc_ASK - cd06624
STKc_PCTAIRE_like - cd07844
PTKc_Tie2 - cd05088
PTKc_VEGFR3 - cd05102
PTKc_VEGFR2 - cd05103
STKc_BUR1 - cd07866
STKc_PCTAIRE3 - cd07871
STKc_CDK12 - cd07864
STKc_MAP4K3 - cd06645
PTKc_ALK_LTK - cd05036
STKc_Sty1_Hog1 - cd07856
PTKc_TrkB - cd05093
PTKc_TrkA - cd05092
PTKc_Lyn - cd05072
PTKc_TrkC - cd05094
PTKc_Ror1 - cd05090
PTKc_Csk - cd05082
PKc_MAPKK_Byr1_like - cd06620
PKc_MEK1 - cd06650
PTKc_Hck - cd05073
PKc_MEK2 - cd06649
STKc_SLK - cd06643
PTKc_DDR1 - cd05096
PTKc_Ror2 - cd05091
PTKc_Src - cd05071
PTKc_FAK - cd05056
PTKc_DDR - cd05051
PTKc_Musk - cd05050
PTKc_Ror - cd05048
PTKc_EphR_A2 - cd05063
PTKc_Trk - cd05049
PTKc_InsR - cd05061
PTKc_Abl - cd05052
PTKc_Fyn_Yrk - cd05070
PTKc_IGF-1R - cd05062
PTK_CCK4 - cd05046
PTKc_Frk_like - cd05068
PTKc_Yes - cd05069
PTKc_EphR_A10 - cd05064
PTKc_Lck_Blk - cd05067
PTKc_EGFR - cd05108
PTKc_HER4 - cd05110
PTKc_HER2 - cd05109
PTK_HER3 - cd05111
STKc_Nek6_Nek7 - cd08224
PTKc_Chk - cd05083
PKc_MKK4 - cd06616
PTKc_Btk_Bmx - cd05113
PTKc_Itk - cd05112
PTKc_Tec_Rlk - cd05114
PTKc_Jak_rpt2 - cd05038
PTKc_Csk_like - cd05039
PTKc_InsR_like - cd05032
PTKc_EphR - cd05033
PTKc_Jak2_Jak3_rpt2 - cd05081
PTK_Ryk - cd05043
PTKc_Src_like - cd05034
PTKc_Tec_like - cd05059
PTKc_EphR_B - cd05065
PTKc_EphR_A - cd05066
PTKc_FGFR - cd05053
PTKc_EGFR_like - cd05057
STKc_PFTAIRE2 - cd07870
STKc_PFTAIRE1 - cd07869
STKc_ERK5 - cd07855
STKc_MST1_2 - cd06612
STKc_MAP4K3_like - cd06613
STKc_ERK1_2_like - cd07849
STKc_TEY_MAPK_plant - cd07858
STKc_MAPK15 - cd07852
STKc_MEKK2 - cd06652
PTKc_Jak1_rpt2 - cd05079
STKc_MEKK3_like_1 - cd06653
STKc_MST4 - cd06640
STKc_MST3 - cd06641
STKc_STK25-YSK1 - cd06642
STKc_MAPKKK_Byr2_lik - cd06628
STKc_NAK1_like - cd06917
PKc_MAPKK_Pek1_like - cd06621
STKc_CdkB_plant - cd07837
PKc_MKK5 - cd06619
PKc_MAPKK_plant_like - cd06623
STKc_Nek6 - cd08228
STKc_Nek9 - cd08221
SPS1 - COG0515
STKc_Nek7 - cd08229
STKc_CDK6 - cd07862
STKc_MAPK4_6 - cd07854
STKc_CDKL5 - cd07848
PKc_MAPKK_PBS2_like - cd06622
STKc_PDK1 - cd05581
STKc_DMPK_like - cd05597
STKc_PKA - cd05580
STKc_phototropin_lik - cd05574
STKc_ROCK_NDR_like - cd05573
PKc_MKK3_6 - cd06617
STKc_CRIK - cd05601
PTKc_Tie1 - cd05089
STKc_MAST - cd05609
PKc_MEK - cd06615
PKc_MAPKK - cd06605
STKc_OSR1_SPAK - cd06610
STKc_NDR1 - cd05628
STKc_PRKX_like - cd05612
STKc_MRCK_alpha - cd05623
STKc_Nek - cd08215
STKc_CDK1_euk - cd07861
STKc_CDK2_3 - cd07860
STKc_Pho85 - cd07836
PK_STRAD - cd08216
STKc_NLK - cd07853
PK_STRAD_beta - cd08226
STKc_MEKK3 - cd06651
STKc_CNK2-like - cd08530
STKc_FA2-like - cd08529
PK_STRAD_alpha - cd08227
STKc_Nek4 - cd08223
STKc_Nek3 - cd08219
STKc_MSK_N - cd05583
STKc_cPKC - cd05587
STKc_Yank1 - cd05578
PKc_STE - cd05122
PTKc_RET - cd05045
STKc_Cdc7_like - cd06627
STKc_MSK1_N - cd05613
STKc_GRK4_like - cd05605
STKc_cPKC_alpha - cd05615
STKc_GRK4 - cd05631
STKc_GRK5 - cd05632
STKc_GRK6 - cd05630
STKc_MSK2_N - cd05614
STKc_MAPKKK - cd06606
STKc_cPKC_beta - cd05616
Pkinase_Tyr - pfam07714
STYKc - smart00221
Pkinase - pfam00069
TyrKc - smart00219
PTKc_Axl - cd05075
STKc_CDK1_like - cd07835
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
STKc_PKN - cd05589
STKc_MST3_like - cd06609
STKc_Nek8 - cd08220
STKc_Nek1 - cd08218
STKc_Nek11 - cd08222
STKc_Nek10 - cd08528
STKc_CDK4 - cd07863
STKc_Nek5 - cd08225
STKc_MEKK3_like - cd06625
STKc_MAPK - cd07834
STKc_CCRK - cd07832
PTKc_Srm_Brk - cd05148
PTKc_Tyk2_rpt2 - cd05080
STKc_CDK5 - cd07839
STKc_CDK7 - cd07841
STKc_MPK1 - cd07857
STKc_CDKL1_4 - cd07847
STKc_CDKL2_3 - cd07846
STKc_CDK8_like - cd07842
STKc_TDY_MAPK_plant - cd07859
STKc_TNIK - cd06637
STKc_MAK_like - cd07830
STKc_MOK - cd07831
STKc_CDK_like - cd07829
STKc_CMGC - cd05118
STKc_CDK9_like - cd07840
STKc_p70S6K - cd05584
STKc_RSK_N - cd05582
STKc_MEKK4 - cd06626
STKc_SGK1 - cd05602
STKc_aPKC_zeta - cd05617
STKc_SGK3 - cd05604
STKc_SGK2 - cd05603
STKc_PKB_alpha - cd05594
STKc_PKB_beta - cd05595
STKc_aPKC_iota - cd05618
STKc_CDK4_6_like - cd07838
STKc_CDK10 - cd07845
STKc_Nek2 - cd08217
STKc_PKB_gamma - cd05593
STKc_YSK4 - cd06631
STKc_MEKK1 - cd06630
STKc_myosinIII_like - cd06608
STKc_nPKC_theta - cd05619
STKc_nPKC_theta_delt - cd05592
PTKc - cd00192
PTKc_Fes_like - cd05041
PTK_Jak2_Jak3_rpt1 - cd05078
PTK_Jak_rpt1 - cd05037
PTKc_Ack_like - cd05040
PTKc_Tie - cd05047
PTKc_c-ros - cd05044
PTKc_Aatyk - cd05042
PTKc_Fes - cd05084
PTKc_Met_Ron - cd05058
STKc_PKB - cd05571
STKc_PKC - cd05570
STKc_SGK - cd05575
STKc_aPKC - cd05588
STKc_nPKC_epsilon - cd05591
STKc_nPKC_eta - cd05590
PTKc_Fer - cd05085
PTKc_Syk - cd05116
PTKc_Syk_like - cd05060
STKc_CDKL - cd07833
PTKc_Zap-70 - cd05115
STKc_beta_ARK - cd05606
STKc_GRK3 - cd05633
STKc_MEKK1_plant - cd06632
STKc_SLK_like - cd06611
STKc_AGC - cd05123
STKc_MAST_like - cd05579
STKc_GRK - cd05577
STKc_cGK_PKG - cd05572
PKc - cd00180
STKc_GRK7 - cd05607
STKc_YPK1_like - cd05585
STKc_GRK1 - cd05608
STKc_Sck1_like - cd05586
STKc_MAPKKK_Bck1_lik - cd06629
S_TKc - smart00220
STKc_CDC2L1 - cd07843
KIND - smart00750


Swiss-Prot Protein: Q13163
Identical to: NP_660143
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PTKc_PDGFR_alphacd051050.0004317425
PB1cd059929.5e-1217107
PB1_Map2k5cd063952.1e-7317107
STKc_ROCK2cd056213.9e-05118442
STKc_ROCKcd055965.7e-05131425
STKc_myosinIIIBcd066395.3e-20140420
STKc_TAO1cd066351.2e-10141444
STKc_TAO3cd066333.3e-09142445
PTKc_DDR2cd050951.1e-06144421
PTKc_DDR_likecd050971.2e-06144421
STKc_PAK1cd066542.4e-11144444
STKc_PAK4cd066572.5e-14144438
STKc_PAK5cd066581.6e-13144436
STKc_PAK6cd066596.3e-14144442
STKc_PAK_Icd066471e-22146442
STKc_PAK2cd066556.6e-16146445
STKc_PAK3cd066564e-12146445
PTKc_FGFR1cd050980.00034148428
STKc_TAOcd066071.6e-14149447
STKc_TAO2cd066344.5e-12149445
STKc_myosinIIIAcd066381.2e-19149419
STKc_p38beta_MAPK11cd078783.9e-05149446
STKc_PAKcd066141.6e-33150430
STKc_MAP4K4_6cd066362.5e-23150419
STKc_STK10_LOKcd066441.2e-30150441
STKc_PAK_IIcd066482.3e-16150432
STKc_JNK2cd078760.00026150443
STKc_p38alpha_MAPK14cd078771.7e-05150446
STKc_JNKcd078501.4e-05151446
STKc_p38cd078511.1e-07152446
PTKc_PDGFRcd050550.00045154400
PKc_MKK7cd066188.7e-67154440
STKc_MAP4K5cd066466.1e-22154418
STKc_p38gamma_MAPK12cd078801.2e-05154446
PTKc_FGFR4cd050990.00011155448
STKc_CDK9cd078652.3e-07155419
PTKc_FGFR2cd051010.00022156428
STKc_ASKcd066246e-27157419
STKc_PCTAIRE1cd078739.8e-07157431
STKc_PCTAIRE2cd078721.2e-07157436
PTKc_Tie2cd050887.2e-06158440
PTKc_VEGFR2cd051035.9e-05158423
PTKc_VEGFR3cd051020.00023158426
STKc_PCTAIRE_likecd078441.6e-07158434
PTKc_ALK_LTKcd050363.9e-09159419
STKc_MAP4K3cd066452.5e-25159418
STKc_Sty1_Hog1cd078563.8e-08159440
STKc_CDK12cd078644.2e-08159419
STKc_BUR1cd078662.5e-05159419
STKc_PCTAIRE3cd078711.3e-07159437
PTK_CCK4cd050460.00032160416
PTKc_Rorcd050489.8e-06160398
PTKc_Trkcd050492e-08160416
PTKc_Muskcd050508.2e-08160422
PTKc_Ablcd050526.6e-09160418
PTKc_FAKcd050561.3e-08160425
PTKc_DDRcd050518.3e-06160421
PTKc_InsRcd050612.5e-05160422
PTKc_IGF-1Rcd050620.00024160421
PTKc_EphR_A10cd050643.5e-06160423
PTKc_Lck_Blkcd050672.8e-06160422
PTKc_Frk_likecd050689.3e-15160422
PTKc_Yescd050691.2e-07160422
PTKc_Fyn_Yrkcd050708.1e-07160422
PTKc_Srccd050719.1e-07160424
PTKc_EphR_A2cd050632.4e-06160419
PTKc_Hckcd050738.6e-07160422
PTKc_Cskcd050821e-07160420
PTKc_Ror1cd050905.3e-05160422
PTKc_Lyncd050724.5e-07160422
PTKc_TrkAcd050923.5e-06160421
PTKc_TrkBcd050933.6e-06160431
PTKc_TrkCcd050943e-05160433
PTKc_Ror2cd050910.00081160422
PTKc_DDR1cd050969.7e-05160421
PKc_MAPKK_Byr1_likecd066204.8e-106160434
STKc_SLKcd066432.5e-22160437
PKc_MEK2cd066494.6e-75160447
PKc_MEK1cd066508.3e-76160446
PTKc_InsR_likecd050329.8e-10161417
PTKc_EphRcd050336.4e-08161419
PTKc_Src_likecd050344.7e-11161422
PTKc_Jak_rpt2cd050381.7e-09161421
PTKc_Csk_likecd050391.7e-07161420
PTK_Rykcd050430.00039161382
PTKc_FGFRcd050532.6e-05161421
PTKc_EGFR_likecd050571.6e-08161432
PTKc_Tec_likecd050591.3e-07161418
PTKc_EphR_Bcd050655.2e-07161419
PTKc_EphR_Acd050661e-05161419
PTKc_Jak2_Jak3_rpt2cd050816.7e-09161421
PTKc_Chkcd050832.6e-07161420
PTKc_EGFRcd051081.9e-07161436
PTKc_HER2cd051091.3e-08161432
PTKc_HER4cd051108.2e-06161424
PTK_HER3cd051113.1e-07161432
PTKc_Itkcd051126.7e-09161418
PTKc_Tec_Rlkcd051142.1e-07161418
PTKc_Btk_Bmxcd051138e-10161418
PKc_MKK4cd066161.8e-72161438
STKc_Nek6_Nek7cd082244.3e-12161428
STKc_MST1_2cd066121.2e-40162419
STKc_MAP4K3_likecd066133.2e-48162418
STKc_ERK5cd078551.3e-05162441
STKc_PFTAIRE1cd078690.00034162424
STKc_PFTAIRE2cd078703.7e-06162434
PTKc_Jak1_rpt2cd050794.3e-05163420
STKc_MST4cd066407.9e-42163441
STKc_MST3cd066414.8e-37163434
STKc_STK25-YSK1cd066423.3e-42163441
STKc_MEKK2cd066521e-09163420
STKc_MEKK3_like_1cd066532.7e-17163419
STKc_ERK1_2_likecd078491.6e-07163445
STKc_MAPK15cd078523.2e-07163433
STKc_TEY_MAPK_plantcd078583.2e-06163447
PTKc_Tie1cd050892.4e-06164448
STKc_ROCK_NDR_likecd055731.2e-08164447
STKc_phototropin_likcd055743.5e-08164383
STKc_PKAcd055807.3e-10164433
STKc_PDK1cd055814.3e-15164419
STKc_DMPK_likecd055970.0004164448
STKc_CRIKcd056012.7e-07164448
STKc_MASTcd056095.2e-07164448
STKc_PRKX_likecd056121.2e-06164447
STKc_NDR1cd056280.00073164444
STKc_MRCK_alphacd056230.00092164436
PKc_MAPKKcd066052.3e-188164424
STKc_OSR1_SPAKcd066105.6e-24164419
PKc_MEKcd066155.4e-107164438
PKc_MKK3_6cd066173.7e-82164439
PKc_MKK5cd066198.3e-222164442
PKc_MAPKK_Pek1_likecd066213e-88164430
PKc_MAPKK_PBS2_likecd066229.3e-88164441
PKc_MAPKK_plant_likecd066235.9e-98164425
STKc_MAPKKK_Byr2_likcd066283.9e-26164419
STKc_NAK1_likecd069176.8e-19164438
STKc_CdkB_plantcd078371.8e-09164420
STKc_CDKL5cd078486.8e-05164419
STKc_MAPK4_6cd078541.8e-05164441
STKc_CDK6cd078620.00021164443
STKc_Nek6cd082282.9e-12164428
STKc_Nek7cd082293e-12164419
STKc_Nek9cd082216.8e-11164419
SPS1COG05151.5e-30164447
PTKc_RETcd050451.2e-05165417
PKc_STEcd051227e-76165418
STKc_Yank1cd055785.1e-16165419
STKc_MSK_Ncd055833.9e-09165435
STKc_cPKCcd055871.7e-05165445
STKc_GRK4_likecd056058.4e-10165447
STKc_MSK1_Ncd056132.2e-06165436
STKc_cPKC_alphacd056156.6e-05165431
STKc_cPKC_betacd056160.00046165420
STKc_MSK2_Ncd056141.1e-05165447
STKc_GRK6cd056301.8e-06165438
STKc_GRK4cd056318.7e-07165438
STKc_GRK5cd056321.8e-06165437
STKc_MAPKKKcd066067.6e-46165419
STKc_Cdc7_likecd066273e-24165419
STKc_MEKK3cd066514.6e-16165421
STKc_Pho85cd078363.5e-07165434
STKc_NLKcd078539.6e-05165448
STKc_CDK2_3cd078609.3e-07165437
STKc_CDK1_eukcd078613.3e-06165419
STKc_Nekcd082152.9e-26165419
PK_STRADcd082167.3e-10165435
STKc_Nek3cd082193.2e-12165419
STKc_Nek4cd082231.4e-07165419
PK_STRAD_alphacd082278.7e-06165436
PK_STRAD_betacd082264.1e-05165435
STKc_FA2-likecd085291.8e-16165419
STKc_CNK2-likecd085302.8e-15165419
PTKc_Axl_likecd050352.1e-05166421
PTKc_Tyro3cd050746.2e-05166421
PTKc_Axlcd050750.00075166421
STKc_PKNcd055891.2e-06166445
STKc_MST3_likecd066094.5e-37166434
STKc_CDK1_likecd078354.4e-07166434
PTKc_Tyk2_rpt2cd050801.3e-05167424
PTKc_Srm_Brkcd051484.1e-08167416
STKc_MEKK3_likecd066254.2e-26167419
STKc_CCRKcd078321.8e-13167420
STKc_MAPKcd078341e-09167440
STKc_CDK5cd078391.8e-08167419
STKc_CDK7cd078418.9e-10167420
STKc_CDK8_likecd078420.00017167419
STKc_CDKL2_3cd078465.6e-11167419
STKc_CDKL1_4cd078472.5e-19167419
STKc_MPK1cd078571.3e-05167441
STKc_TDY_MAPK_plantcd078591.5e-05167448
STKc_CDK4cd078633.9e-06167419
STKc_Nek1cd082182.4e-08167419
STKc_Nek8cd082202.1e-09167419
STKc_Nek11cd082226.8e-14167419
STKc_Nek5cd082258.9e-18167419
STKc_Nek10cd085285.6e-08167419
STKc_CMGCcd051187.5e-16168419
STKc_TNIKcd066372.1e-24168419
STKc_CDK_likecd078293.9e-14168419
STKc_MAK_likecd078304.5e-08168419
STKc_MOKcd078312.7e-08168419
STKc_CDK9_likecd078401.2e-09168419
STKc_RSK_Ncd055824.2e-05169445
STKc_p70S6Kcd055840.0001169447
STKc_MEKK4cd066264.6e-18169419
PTKccd001925.7e-12170418
PTK_Jak_rpt1cd050370.0003170414
PTKc_Ack_likecd050404e-11170415
PTKc_Aatykcd050429.8e-05170416
PTKc_c-roscd050441e-06170415
PTKc_Tiecd050470.00012170427
PTKc_Fes_likecd050412.1e-10170419
PTKc_Met_Roncd050583.7e-05170423
PTK_Jak2_Jak3_rpt1cd050787.2e-06170423
PTKc_Fescd050847.3e-08170419
PTKc_Fercd050851.3e-08170419
PTKc_Syk_likecd050602.3e-07170424
PTKc_Sykcd051168.7e-06170419
STKc_PKCcd055709.4e-11170434
STKc_PKBcd055714.4e-06170447
STKc_SGKcd055752e-05170447
STKc_aPKCcd055881.1e-06170445
STKc_nPKC_etacd055904.5e-05170446
STKc_nPKC_epsiloncd055916.7e-06170446
STKc_nPKC_theta_deltcd055921.6e-05170447
STKc_PKB_gammacd055931.9e-05170448
STKc_PKB_alphacd055942.2e-05170444
STKc_PKB_betacd055950.00013170448
STKc_SGK2cd056036.6e-06170448
STKc_SGK3cd056043.7e-05170448
STKc_SGK1cd056022.7e-05170448
STKc_aPKC_zetacd056171.5e-06170445
STKc_aPKC_iotacd056189.8e-05170445
STKc_nPKC_thetacd056194e-06170447
STKc_myosinIII_likecd066082.6e-24170419
STKc_MEKK1cd066302.2e-13170420
STKc_YSK4cd066312.3e-15170419
STKc_CDK4_6_likecd078384.7e-08170419
STKc_CDK10cd078451.1e-05170417
STKc_Nek2cd082171.9e-14170419
PTKc_Zap-70cd051152.9e-06171422
STKc_beta_ARKcd056068.3e-08171440
STKc_GRK3cd056333e-06171441
STKc_CDKLcd078331.3e-12171419
PKccd001802.1e-67172417
STKc_AGCcd051233.7e-16172419
STKc_cGK_PKGcd055721.5e-15172426
STKc_GRKcd055772.7e-09172424
STKc_MAST_likecd055791.3e-15172424
STKc_YPK1_likecd055857.4e-05172447
STKc_Sck1_likecd055860.00095172448
STKc_GRK1cd056082.5e-10172437
STKc_GRK7cd056071.2e-07172436
STKc_SLK_likecd066113.3e-17172436
STKc_MEKK1_plantcd066327.4e-18172419
STKc_MAPKKK_Bck1_likcd066291.6e-13173419
STKc_CDC2L1cd078433.4e-07178419
PB1pfam005641.6e-141897
Pkinasepfam000699.7e-69166419
PB1smart006663e-121895
Pkinase_Tyrpfam077141.5e-16166419
TyrKcsmart002195.1e-15166417
STYKcsmart002213.6e-62166419
S_TKcsmart002207.2e-67176419
KINDsmart007501e-06247427

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_046070Polymorphismp.ALA428THRN/A
Swiss-ProtVAR_040824Polymorphismp.ALA427VALN/A
Swiss-ProtVAR_040823Polymorphismp.HIS118ARGN/A



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