Results for the protein: Q01973

Results for the Protein: Q01973

118572711

4919

ROR1

NCBI, UniProt

ROR1_HUMAN RecName: Full=Tyrosine-protein kinase transmembrane receptor ROR1; AltName: Full=Neurotrophic tyrosine kinase, receptor-related 1; Flags: Precursor

			0 9 0 1 8

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Swiss-Prot Protein: Q01973

Identical to: NP_005003

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Ig4_PDGFR-alpha	cd05859	0.00051	57	150
Ig1_NCAM-1_like	cd04977	0.00047	58	148
Ig3_Contactin_like	cd04968	0.00023	59	149
Ig1_Contactin	cd04967	0.0004	60	146
Ig1_Neogenin	cd05722	6.9e-05	60	148
Ig1_Robo	cd07693	0.001	60	149
Ig2_Robo	cd05724	0.00023	61	148
Ig4_Contactin-2-like	cd05728	6.6e-05	62	148
Ig2_FGFR_like	cd05729	2.4e-06	64	148
Ig2_FGFRL1-like	cd05856	0.00089	64	148
Ig_Myomesin_like_C	cd05737	0.00042	67	145
Ig2_FGFR	cd05857	0.00029	67	148
Ig5_Contactin_like	cd04969	0.00022	72	148
Ig4_L1-NrCAM_like	cd04978	4.9e-07	72	140
Ig_Perlecan_D2_like	cd05743	0.00015	72	148
Ig3_Peroxidasin	cd05745	0.00011	72	148
Ig_2	cd05764	0.00053	72	148
Ig_Titin_like	cd05748	0.00032	74	148
Ig	cd00096	4.6e-14	75	145
Ig3_Robo	cd05725	8.2e-06	75	148
Ig2_Follistatin_like	cd05736	5.7e-06	75	151
Ig2_RPTP_IIa_LAR_lik	cd05738	0.00033	75	149
Ig_1	cd05763	0.0002	75	149
Ig_Myotilin_C_like	cd05744	0.00018	75	148
Ig2_VEGFR-2	cd05864	0.00054	75	148
Ig_Palladin_C	cd05893	0.00028	75	148
Ig4_Neogenin	cd05723	0.00045	77	148
CRD_TK_ROR1	cd07467	1.4e-122	166	307
CRD_TK_ROR_related	cd07469	5e-07	166	305
CRD_TK_ROR2	cd07468	2.9e-100	166	305
CRD_TK_ROR_like	cd07459	3.1e-74	168	302
CRD_FZ	cd07066	3.6e-12	169	301
KR	cd00108	2.7e-47	310	392
PTKc_PDGFR_alpha	cd05105	8.5e-14	441	752
PTKc_CSF-1R	cd05106	5.4e-36	442	751
PTKc_Kit	cd05104	6.7e-22	444	750
PTKc_PDGFR_beta	cd05107	1.8e-09	444	751
PTKc_PDGFR	cd05055	9.2e-19	445	750
STKc_PAK1	cd06654	0.00056	451	769
STKc_PAK3	cd06656	0.00067	452	771
PTKc_FGFR1	cd05098	4e-48	456	757
STKc_TAO	cd06607	0.00077	457	792
STKc_PAK_II	cd06648	8.9e-05	457	759
PTKc_FGFR2	cd05101	5.1e-48	458	757
STKc_PAK	cd06614	1.1e-07	458	753
STKc_STK10_LOK	cd06644	5.4e-05	459	772
STKc_TAO2	cd06634	0.00012	460	793
PTKc_FGFR	cd05053	4.1e-49	461	753
PTKc_FGFR4	cd05099	1.8e-56	461	762
PTKc_FGFR3	cd05100	1.5e-43	461	787
PKc_MKK7	cd06618	5.1e-05	462	770
STKc_MAP4K3	cd06645	0.00013	463	747
STKc_MAP4K5	cd06646	0.00038	463	747
STKc_ASK	cd06624	2.9e-05	464	748
PTKc_EGFR_like	cd05057	7.5e-44	465	760
PTKc_VEGFR	cd05054	5.4e-24	465	753
PTKc_VEGFR2	cd05103	8.1e-24	465	753
PTKc_VEGFR3	cd05102	1.1e-25	465	753
PTKc_EGFR	cd05108	1.4e-27	465	792
PTKc_HER2	cd05109	2.1e-33	465	760
PTK_HER3	cd05111	2.9e-32	465	760
STKc_PAK6	cd06659	0.00016	465	773
PTKc_FAK	cd05056	2.1e-71	466	754
PTKc_ALK_LTK	cd05036	1.6e-76	466	748
PTKc_HER4	cd05110	8.5e-25	466	777
STKc_TNIK	cd06637	0.00016	466	746
STKc_CDK12	cd07864	2.1e-07	466	757
PTKc_InsR_like	cd05032	2.8e-83	467	748
PTKc_Src_like	cd05034	1.1e-56	467	749
PTKc_Csk_like	cd05039	1.3e-41	467	749
PTKc_Ror	cd05048	1.6e-243	467	749
PTKc_Trk	cd05049	3.5e-125	467	748
PTKc_Musk	cd05050	1.5e-117	467	748
PTKc_DDR	cd05051	5.6e-74	467	748
PTKc_Abl	cd05052	5.9e-65	467	750
PTK_CCK4	cd05046	3.2e-66	467	748
PTKc_InsR	cd05061	1.2e-59	467	759
PTKc_IGF-1R	cd05062	1.1e-61	467	748
PTKc_EphR_A2	cd05063	1.6e-62	467	750
PTKc_EphR_A10	cd05064	6.3e-51	467	750
PTKc_Lck_Blk	cd05067	2.5e-50	467	749
PTKc_Frk_like	cd05068	9.1e-71	467	749
PTKc_Fyn_Yrk	cd05070	6.5e-47	467	749
PTKc_Src	cd05071	1.1e-45	467	751
PTKc_Lyn	cd05072	1.1e-47	467	749
PTKc_Hck	cd05073	2.8e-43	467	749
PTKc_Yes	cd05069	4.8e-43	467	749
PTKc_Csk	cd05082	6.9e-46	467	749
PTKc_Ror1	cd05090	7.1e-262	467	749
PTKc_Ror2	cd05091	4.8e-172	467	749
PTKc_TrkA	cd05092	1.3e-90	467	748
PTKc_TrkB	cd05093	3.7e-84	467	758
PTKc_DDR2	cd05095	5.3e-73	467	748
PTKc_DDR1	cd05096	1.1e-64	467	748
PTKc_DDR_like	cd05097	3.7e-70	467	748
PTKc_TrkC	cd05094	5e-62	467	758
PTKc_Srm_Brk	cd05148	1.5e-53	467	749
STKc_SLK_like	cd06611	1.3e-05	467	745
PKc_MAPKK_Byr1_like	cd06620	0.00021	467	750
STKc_SLK	cd06643	0.00018	467	770
PTKc_EphR	cd05033	3.5e-74	468	750
PTKc_Jak_rpt2	cd05038	7.6e-55	468	750
PTKc_Tec_like	cd05059	1e-44	468	747
PTKc_EphR_A	cd05066	4.4e-64	468	750
PTKc_Chk	cd05083	1.8e-56	468	749
PTKc_Tie2	cd05088	3.6e-40	468	766
PTKc_EphR_B	cd05065	1.6e-65	468	750
PTKc_Btk_Bmx	cd05113	1.6e-55	468	747
PTKc_Tec_Rlk	cd05114	4.6e-50	468	747
PTKc_Itk	cd05112	4.6e-54	468	747
STKc_myosinIII_like	cd06608	0.00029	468	746
STKc_MAP4K3_like	cd06613	3.7e-08	469	743
STKc_MST4	cd06640	6e-05	469	770
STKc_MST3	cd06641	6.6e-06	469	766
STKc_MEKK3	cd06651	0.00013	469	746
STKc_STK25-YSK1	cd06642	1.9e-05	469	770
STKc_PCTAIRE_like	cd07844	3.8e-07	469	778
PTKc_Tie1	cd05089	1.7e-40	470	765
STKc_MST1_2	cd06612	3.7e-07	470	742
STKc_BUR1	cd07866	0.00066	470	739
STKc_PCTAIRE3	cd07871	3.6e-06	470	778
STKc_PCTAIRE1	cd07873	8e-05	470	788
STKc_PCTAIRE2	cd07872	2e-05	470	784
STKc_Nek6_Nek7	cd08224	1.7e-07	470	751
STKc_Nek6	cd08228	1.2e-05	470	751
STKc_Nek7	cd08229	6.9e-07	470	751
PTK_Ryk	cd05043	2.6e-25	471	752
STKc_ROCK_NDR_like	cd05573	0.00043	471	784
STKc_MAST	cd05609	3.6e-05	471	806
STKc_PRKX_like	cd05612	0.0006	471	777
PKc_MAPKK	cd06605	1.1e-05	471	744
STKc_MAPKKK	cd06606	2e-14	471	740
STKc_MST3_like	cd06609	1.3e-06	471	757
STKc_OSR1_SPAK	cd06610	2.1e-08	471	742
PKc_MKK3_6	cd06617	0.00038	471	762
PKc_MAPKK_PBS2_like	cd06622	2.1e-07	471	785
PKc_MAPKK_plant_like	cd06623	4.1e-08	471	751
PKc_MAPKK_Pek1_like	cd06621	0.00075	471	749
STKc_MEKK2	cd06652	0.00011	471	759
STKc_NAK1_like	cd06917	1.2e-06	471	747
STKc_CdkB_plant	cd07837	7.9e-07	471	787
STKc_CDK10	cd07845	1.6e-07	471	823
STKc_CDKL1_4	cd07847	2.3e-05	471	787
STKc_CDK6	cd07862	0.00018	471	778
STKc_PFTAIRE2	cd07870	8.8e-07	471	777
STKc_PFTAIRE1	cd07869	0.00073	471	791
SPS1	COG0515	1e-27	471	908
PTKc_RET	cd05045	4.4e-44	472	753
PTKc_Jak1_rpt2	cd05079	1.7e-31	472	750
PKc_STE	cd05122	1.1e-11	472	757
STKc_MSK_N	cd05583	2.4e-05	472	777
STKc_GRK4_like	cd05605	2.6e-06	472	786
STKc_MSK1_N	cd05613	2.2e-05	472	792
STKc_MSK2_N	cd05614	0.00014	472	808
STKc_GRK5	cd05632	0.00035	472	761
STKc_Cdc7_like	cd06627	4.3e-10	472	746
STKc_Pho85	cd07836	4.5e-06	472	786
STKc_CDK1_euk	cd07861	1.3e-05	472	786
STKc_CDK4	cd07863	6.4e-05	472	778
STKc_CDK2_3	cd07860	1.4e-05	472	778
STKc_Nek1	cd08218	0.00027	472	748
STKc_Nek3	cd08219	2.3e-08	472	748
STKc_Nek4	cd08223	6e-05	472	748
STKc_Nek5	cd08225	1.4e-05	472	748
STKc_Nek10	cd08528	0.00017	472	748
PTKc_Axl_like	cd05035	5e-52	473	750
PTKc_Tyro3	cd05074	3.3e-54	473	750
PTKc_Axl	cd05075	1.6e-44	473	750
PTKc_Jak2_Jak3_rpt2	cd05081	1.4e-34	473	750
STKc_PKN	cd05589	0.00037	473	806
STKc_MAPKKK_Bck1_lik	cd06629	7.5e-10	473	740
STKc_CDK1_like	cd07835	5e-08	473	792
PTKc_Tyk2_rpt2	cd05080	1.5e-24	474	751
STKc_PDK1	cd05581	4.4e-10	474	752
STKc_Yank1	cd05578	3.8e-05	474	758
STKc_MAPKKK_Byr2_lik	cd06628	2.5e-07	474	746
STKc_CDK_like	cd07829	3.6e-10	474	742
STKc_MAK_like	cd07830	3.8e-08	474	739
STKc_CCRK	cd07832	9.2e-05	474	740
STKc_MOK	cd07831	0.00072	474	739
STKc_Nek11	cd08222	2.8e-06	474	749
STKc_CNK2-like	cd08530	2.7e-05	474	746
STKc_CDK8_like	cd07842	2.4e-05	475	739
STKc_CDK7	cd07841	5.2e-08	475	768
STKc_FA2-like	cd08529	7.1e-07	475	749
STKc_CMGC	cd05118	8.2e-09	476	753
STKc_p70S6K	cd05584	0.00039	476	808
STKc_RSK_N	cd05582	8.6e-05	476	817
STKc_CDK4_6_like	cd07838	3.4e-06	476	753
STKc_CDK5	cd07839	1.1e-06	476	792
STKc_Nek	cd08215	1.9e-12	476	748
STKc_Nek2	cd08217	3.4e-07	476	746
PTKc	cd00192	5.1e-138	477	747
PTK_Jak_rpt1	cd05037	6e-11	477	747
PTKc_Ack_like	cd05040	3.8e-57	477	748
PTKc_Aatyk	cd05042	1.8e-23	477	749
PTKc_Tie	cd05047	1.6e-49	477	750
PTKc_Fes_like	cd05041	4.2e-57	477	748
PTKc_Met_Ron	cd05058	6.6e-56	477	752
PTKc_Syk_like	cd05060	1.1e-65	477	751
PTK_Tyk2_rpt1	cd05076	1.3e-05	477	747
PTK_Jak1_rpt1	cd05077	7.7e-08	477	747
PTKc_Fes	cd05084	1.6e-64	477	748
PTKc_Fer	cd05085	6.2e-60	477	748
PTKc_Aatyk2	cd05086	1.2e-29	477	749
PTKc_Aatyk1_Aatyk3	cd05087	1.2e-33	477	748
PTK_Jak2_Jak3_rpt1	cd05078	3.4e-12	477	747
PTKc_Syk	cd05116	3.1e-57	477	751
STKc_PKB	cd05571	0.00061	477	839
STKc_nPKC_theta_delt	cd05592	0.00016	477	794
STKc_nPKC_theta	cd05619	2.3e-05	477	819
STKc_MEKK1	cd06630	6.4e-05	477	747
STKc_YSK4	cd06631	7.3e-07	477	744
STKc_MEKK1_plant	cd06632	8.9e-08	477	744
STKc_CDK9_like	cd07840	2.3e-05	477	755
PTKc_Zap-70	cd05115	1.7e-54	478	751
PKc	cd00180	1.7e-49	479	746
PTKc_c-ros	cd05044	2.7e-64	479	748
STKc_AGC	cd05123	1.4e-09	479	743
STKc_PKC	cd05570	0.00023	479	792
STKc_cGK_PKG	cd05572	5.8e-06	479	751
STKc_GRK	cd05577	3.6e-05	479	745
STKc_MAST_like	cd05579	7.2e-08	479	744
STKc_beta_ARK	cd05606	2.7e-05	479	778
STKc_GRK1	cd05608	2.8e-05	479	772
STKc_GRK3	cd05633	0.00021	479	785
STKc_MEKK4	cd06626	3e-05	479	744
STKc_MEKK3_like	cd06625	7.6e-08	479	742
STKc_Nek8	cd08220	8.6e-06	479	748
STKc_Nek9	cd08221	3.4e-06	479	748
ig	pfam00047	1.1e-09	72	133
Fz	pfam01392	9.7e-47	170	297
Kringle	pfam00051	5.2e-34	313	391
Pkinase	pfam00069	1.4e-33	473	746
I-set	pfam07679	3e-19	58	148
IG	smart00409	3.3e-17	64	149
IG_like	smart00410	3.3e-17	64	149
V-set	pfam07686	4.1e-05	66	149
IGc2	smart00408	4.3e-17	71	138
KR	smart00130	8.3e-48	311	393
Pkinase_Tyr	pfam07714	1.7e-143	473	746
TyrKc	smart00219	2.5e-141	473	746
STYKc	smart00221	3.6e-48	473	750
S_TKc	smart00220	8.2e-37	483	750

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041783	Polymorphism	p.ARG567ILE	N/A
Swiss-Prot	VAR_035713	Polymorphism	p.GLU562ASP	N/A
Swiss-Prot	VAR_041784	Polymorphism	p.GLY624ARG	N/A
Swiss-Prot	VAR_041779	Polymorphism	p.GLY144GLU	N/A
Swiss-Prot	VAR_041781	Polymorphism	p.ILE301VAL	N/A
Swiss-Prot	VAR_041780	Polymorphism	p.PHE150LEU	N/A
Swiss-Prot	VAR_041786	Polymorphism	p.SER776ASN	N/A
dbSNP	rs7527017	Polymorphism	p.THR518MET	N/A
Swiss-Prot	VAR_041785	Polymorphism	p.TYR646CYS	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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