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Results for the Protein: P25445
119833
355
FAS

TNR6_HUMAN RecName: Full=Tumor necrosis factor receptor superfamily member 6; AltName: Full=Apo-1 antigen; AltName: Full=Apoptosis-mediating surface antigen FAS; AltName: Full=FASLG receptor; AltName: CD_antigen=CD95; Flags: Precursor

Known Diseases associated with this Protein:
  AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME 1A (ALPS1A)
22
14
0
1
35
Tips:
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Default View:

TNFR - cd00185
TNFR_c6 - pfam00020
TNFR - smart00208
Death_FAS_TNFRSF6 - cd08316
DEATH - smart00005
Death - pfam00531
Death - cd01670
Death_DRs - cd08784
Death_TNFR1 - cd08313
Death_FADD - cd08306


Swiss-Prot Protein: P25445
Identical to: NP_000034
   Default View:









Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
TNFRcd001854e-3048147
Death_FAS_TNFRSF6cd083169.2e-61223319
Deathcd016703e-05232312
Death_DRscd087849e-41232311
Death_TNFR1cd083132.3e-05235311
Death_FADDcd083060.00014239315
TNFR_c6pfam000201.2e-1485127
TNFR_c6pfam000208.8e-09129165
Deathpfam005314.6e-20231314
TNFRsmart002081.2e-1285127
TNFRsmart002082.1e-07129165
DEATHsmart000057.1e-22225313

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_013428Diseasep.ALA257ASPAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
dbSNPrs3218619 Polymorphismp.ALA16THRN/A
Swiss-ProtVAR_013416Polymorphismp.ALA25THRN/A
Swiss-ProtVAR_013427Diseasep.ARG250GLNAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013426Diseasep.ARG250PROAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013419Diseasep.ARG121TRPAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_018323Polymorphismp.ASN255ASPN/A
Swiss-ProtVAR_013432Polymorphismp.ASN264LYSN/A
Swiss-ProtVAR_018321Polymorphismp.ASN118SERN/A
Swiss-ProtVAR_013429Diseasep.ASP260GLYAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013430Diseasep.ASP260TYRAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013431Diseasep.ASP260VALAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_018322Polymorphismp.CYS178ARGN/A
Swiss-ProtVAR_013418Diseasep.CYS82ARGAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013434Diseasep.GLU272GLYAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013435Diseasep.GLU272LYSAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_065129Diseasep.GLY253ASPAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_065130Diseasep.GLY253SERAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_065131Diseasep.ILE259ARGAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_058910Diseasep.ILE262SERAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013438Diseasep.ILE310SERAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_052347Polymorphismp.ILE184VALN/A
Swiss-ProtVAR_013420Polymorphismp.LEU180PHEN/A
Swiss-ProtVAR_013436Polymorphismp.LEU278PHEN/A
Swiss-ProtVAR_013437Polymorphismp.LYS299ASNN/A
Swiss-ProtVAR_013421Polymorphismp.PRO183LEUN/A
Swiss-ProtVAR_013417Diseasep.THR28ALAAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_020009Polymorphismp.THR122ILEN/A
Swiss-ProtVAR_013422Polymorphismp.THR198ILEN/A
Swiss-ProtVAR_013433Diseasep.THR270ILEAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_020942Polymorphismp.THR305ILEN/A
Swiss-ProtVAR_013424Diseasep.THR241LYSAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_065132Diseasep.THR270LYSAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013425Diseasep.THR241PROAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_013423Diseasep.TYR232CYSAutoimmune lymphoproliferative syndrome 1A (ALPS1A)
Swiss-ProtVAR_065128Diseasep.VAL249LEUAutoimmune lymphoproliferative syndrome 1A (ALPS1A)



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